Molecular Target Synopsis
Overview
Domains and Structures
Drugs and Clinical Candidates
Druggability
Chemistry
Ligand Efficiency Plot
Pathways
Family Cladogram
Interaction Network
Gene Expression
Gene Copy Number Variation
RNAi
Mutations
Germline Genetics

rpsJ (Q5SHN7) - Overview - Molecular Target Synopsis

Protein


rpsJ, 30S ribosomal protein S10
UniProt Q5SHN7

Also Known as RS10_THET8, rpsJ

Involved in the binding of tRNA to the ribosomes (By similarity). Part of the top of the 30S subunit head. Part of the 30S ribosomal subunit. Forms a tight complex with proteins S3 and S14. Also contacts protein S9.

6MPF
STRUCTURE OF THE THERMUS THERMOPHILUS 30S RIBOSOMAL SUBUNIT COMPLEXED WITH A 2-THIOCYTIDINE (S2C32) AND INOSINE (I34) MODIFIED ANTICODON STEM LOOP (ASL) OF ESCHERICHIA COLI TRANSFER RNA ARGININE 1 (TRNAARG1) BOUND TO AN MRNA WITH AN CGC-CODON IN THE A-SITE AND PAROMOMYCIN
RCSB/PDB
Inspect Structure
See all 3D Structures for rpsJ

Isoforms / Transcripts (Protein Coding)


Protein Length Ensembl Gene Ensembl Transcript Ensembl Protein Uniprot Isoform

Sub-cellular localization


GO terms: rpsJ is active in the following subcellular-locations: ribosome.



UniProt
GO terms

Gene Copy Number Variation


In COSMIC - Cell Lines Project rpsJ has gain in 0 cell-lines, loss in 0 cell-lines and no signal in 0 cell-lines. (see details)

3D Structures


For rpsJ there are:
123 structures (123 chains) solved
4 are solved in complex with at least one small molecule ligand



(see details)
Molecular Target 3D Synopsis