Molecular Target Synopsis
Overview
Domains and Structures
Drugs and Clinical Candidates
Druggability
Chemistry
Ligand Efficiency Plot
Pathways
Family Cladogram
Interaction Network
Gene Expression
Gene Copy Number Variation
RNAi
Mutations
Germline Genetics

Mup20 (Q5FW60) - Overview - Molecular Target Synopsis

Protein


Mup20, Major urinary protein 20
UniProt Q5FW60

Also Known as MUP20_MOUSE, Mup20, Mup24

Male pheromone which stimulates female sexual attraction to male urinary scent and promotes a strong learned attraction to the airborne urinary odor of an individual male. Promotes male aggressive behavior. Binds most of the male pheromone, 2-sec-butyl-4,5-dihydrothiazole, in urine.

2L9C
STRUCTURAL INSIGHTS INTO THE SPECIFICITY OF DARCIN, AN ATYPICAL MAJOR URINARY PROTEIN.
RCSB/PDB
Inspect Structure
See all 3D Structures for Mup20

Isoforms / Transcripts (Protein Coding)


Protein Length Ensembl Gene Ensembl Transcript Ensembl Protein Uniprot Isoform
181Q5FW60-1

Sub-cellular localization


UniProt: Mup20 is active in the following subcellular-locations: secreted.
GO terms: Mup20 is active in the following subcellular-locations: cytosol, extracellular region, extracellular space, nucleus.



UniProt
GO terms

Gene Copy Number Variation


In COSMIC - Cell Lines Project Mup20 has gain in 0 cell-lines, loss in 0 cell-lines and no signal in 0 cell-lines. (see details)

3D Structures


For Mup20 there are:
1 structures (1 chains) solved
0 are solved in complex with at least one small molecule ligand



(see details)
Molecular Target 3D Synopsis

Screening and Chemistry


Mup20 has been screened with compounds ( bioactivities). (see details)