Molecular Target Synopsis
Overview
Domains and Structures
Drugs and Clinical Candidates
Druggability
Chemistry
Ligand Efficiency Plot
Pathways
Family Cladogram
Interaction Network
Gene Expression
Gene Copy Number Variation
RNAi
Mutations
Germline Genetics

MEST (Q5EB52) - Overview - Molecular Target Synopsis

Protein


MEST, Mesoderm-specific transcript homolog protein
Enzyme Classification 3.-.-.-
UniProt Q5EB52

Also Known as MEST_HUMAN, MEST, PEG1

Isoforms / Transcripts (Protein Coding)


Sub-cellular localization


UniProt: MEST is active in the following subcellular-locations: endoplasmic reticulum membrane.
GO terms: MEST is active in the following subcellular-locations: endoplasmic reticulum, endoplasmic reticulum membrane, extracellular exosome, integral component of membrane.



UniProt
GO terms

Gene Copy Number Variation


In COSMIC - Cell Lines Project MEST has gain in 4 cell-lines, loss in 0 cell-lines and no signal in 1001 cell-lines. (see details)

Gene Expression


In NCI60, the highest expressing cell lines are: SF_268, OVCAR_3, MCF7

In Array Express (RNA-seq of 675 commonly used human cancer cell lines), the highest expressing cell lines are: DMS 79, SJCRH30, COR-L279

In Array Express (RNA-seq of long poly adenylated RNA and long non poly adenylated RNA from ENCODE cell lines), the highest expressing cell lines are: HSMM, NHLF, IMR-90

(see details)