mycG (Q59523) - Overview - Molecular Target Synopsis
mycG, Mycinamicin IV hydroxylase/epoxidase
Enzyme Classification 1.14.-.-
Also Known as MYCG_MICGR, mycG
Involved in the biosynthesis of mycinamicin, a 16-membered macrolide antibiotic. Catalyzes consecutive hydroxylation (at C14) and epoxidation (at C12-C13) reactions with mycinamicin IV as initial substrate, leading to mycinamicin II. These reactions require prior dimethylation of 6-deoxyallose to mycinose for effective conversion by the dual function MycG enzyme.
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