Molecular Target Synopsis
Overview
Domains and Structures
Drugs and Clinical Candidates
Druggability
Chemistry
Ligand Efficiency Plot
Pathways
Family Cladogram
Interaction Network
Gene Expression
Gene Copy Number Variation
RNAi
Mutations
Germline Genetics

NAALADL2 (Q58DX5) - Overview - Molecular Target Synopsis

Protein


NAALADL2, Inactive N-acetylated-alpha-linked acidic dipeptidase-like protein 2
UniProt Q58DX5

Also Known as NADL2_HUMAN, NAALADL2

May be catalytically inactive.

Isoforms / Transcripts (Protein Coding)


Sub-cellular localization


UniProt: NAALADL2 is active in the following subcellular-locations: membrane.
GO terms: NAALADL2 is active in the following subcellular-locations: integral component of membrane, nucleoplasm.



UniProt
GO terms

Gene Copy Number Variation


In COSMIC - Cell Lines Project NAALADL2 has gain in 15 cell-lines, loss in 2 cell-lines and no signal in 987 cell-lines. (see details)

Gene Expression


In NCI60, the highest expressing cell lines are: TK_10, ACHN, MOLT_4

In Array Express (RNA-seq of 675 commonly used human cancer cell lines), the highest expressing cell lines are: HCC2688, OVMANA, OAW28

In Array Express (RNA-seq of long poly adenylated RNA and long non poly adenylated RNA from ENCODE cell lines), the highest expressing cell lines are: GM12878, SK-N-SH, NHLF

(see details)