Molecular Target Synopsis
Overview
Domains and Structures
Drugs and Clinical Candidates
Druggability
Chemistry
Ligand Efficiency Plot
Pathways
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Interaction Network
Gene Expression
Gene Copy Number Variation
RNAi
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hmd (Q58194) - Overview - Molecular Target Synopsis

Protein


hmd, 5,10-methenyltetrahydromethanopterin hydrogenase
Enzyme Classification 1.12.98.2
UniProt Q58194

Also Known as HMD_METJA, hmd

Catalyzes the reversible reduction of methenyl-H(4)MPT(+) to methylene-H(4)MPT.

3H65
THE CRYSTAL STRUCTURE OF C176A MUTATED [FE]-HYDROGENASE (HMD) HOLOENZYME IN COMPLEX WITH METHYLENETETRAHYDROMETHANOPTERIN
RCSB/PDB
Inspect Structure
See all 3D Structures for hmd

Isoforms / Transcripts (Protein Coding)


Protein Length Ensembl Gene Ensembl Transcript Ensembl Protein Uniprot Isoform
358Q58194-1

Gene Copy Number Variation


In COSMIC - Cell Lines Project hmd has gain in 0 cell-lines, loss in 0 cell-lines and no signal in 0 cell-lines. (see details)

3D Structures


For hmd there are:
6 structures (6 chains) solved
5 are solved in complex with at least one small molecule ligand



(see details)
Molecular Target 3D Synopsis