Molecular Target Synopsis
Overview
Domains and Structures
Drugs and Clinical Candidates
Druggability
Chemistry
Ligand Efficiency Plot
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Gene Expression
Gene Copy Number Variation
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pdxS (Q58090) - Overview - Molecular Target Synopsis

Protein


pdxS, Pyridoxal 5'-phosphate synthase subunit PdxS
Enzyme Classification 4.3.3.6
UniProt Q58090

Also Known as PDXS_METJA, pdxS

Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively. In the presence of PdxT, forms a dodecamer of heterodimers.

2YZR
CRYSTAL STRUCTURE OF PYRIDOXINE BIOSYNTHESIS PROTEIN FROM METHANOCALDOCOCCUS JANNASCHII
RCSB/PDB
Inspect Structure
See all 3D Structures for pdxS

Isoforms / Transcripts (Protein Coding)


Protein Length Ensembl Gene Ensembl Transcript Ensembl Protein Uniprot Isoform
330Q58090-1

Gene Copy Number Variation


In COSMIC - Cell Lines Project pdxS has gain in 0 cell-lines, loss in 0 cell-lines and no signal in 0 cell-lines. (see details)

3D Structures


For pdxS there are:
1 structures (3 chains) solved
0 are solved in complex with at least one small molecule ligand



(see details)
Molecular Target 3D Synopsis