Molecular Target Synopsis
Overview
Domains and Structures
Drugs and Clinical Candidates
Druggability
Chemistry
Ligand Efficiency Plot
Pathways
Family Cladogram
Interaction Network
Gene Expression
Gene Copy Number Variation
RNAi
Mutations
Germline Genetics

cheA (Q56310) - Overview - Molecular Target Synopsis

Protein


cheA, Chemotaxis protein CheA
Enzyme Classification 2.7.13.3
UniProt Q56310

Also Known as CHEA_THEMA, cheA

Involved in the transmission of sensory signals from the chemoreceptors to the flagellar motors. CheA is autophosphorylated; it can transfer its phosphate group to either CheB or CheY.

6MI6
STRUCTURE OF CHEA DOMAIN P4 IN COMPLEX WITH AN ADP ANALOG
RCSB/PDB
Inspect Structure
See all 3D Structures for cheA

Isoforms / Transcripts (Protein Coding)


Protein Length Ensembl Gene Ensembl Transcript Ensembl Protein Uniprot Isoform
671Q56310-1

Sub-cellular localization


UniProt: cheA is active in the following subcellular-locations: cytoplasm.
GO terms: cheA is active in the following subcellular-locations: cytoplasm.



UniProt
GO terms

Gene Copy Number Variation


In COSMIC - Cell Lines Project cheA has gain in 0 cell-lines, loss in 0 cell-lines and no signal in 0 cell-lines. (see details)

3D Structures


For cheA there are:
16 structures (28 chains) solved
9 are solved in complex with at least one small molecule ligand



(see details)
Molecular Target 3D Synopsis