Molecular Target Synopsis
Overview
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Chemistry
Ligand Efficiency Plot
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cse3 (Q53WG9) - Overview - Molecular Target Synopsis

Protein


cse3, CRISPR-associated endoribonuclease Cse3
Enzyme Classification 3.1.-.-
UniProt Q53WG9

Also Known as CAS6_THET8, cse3, cas6

CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). This enzyme processes pre-crRNA into individual crRNA units, but may not actually undergo enzyme turnover, retaining the crRNA product (PubMed:21572442). Generates a 2',3'-cyclic phosphodiester. Probably part of the Cascade ribonucleoprotein complex (Probable). Monomer, retains crRNA after it is processed.

3QRP
STRUCTURE OF THERMUS THERMOPHILUS CSE3 BOUND TO AN RNA REPRESENTING A PRODUCT MIMIC COMPLEX
RCSB/PDB
Inspect Structure
See all 3D Structures for cse3

Isoforms / Transcripts (Protein Coding)


Protein Length Ensembl Gene Ensembl Transcript Ensembl Protein Uniprot Isoform
211Q53WG9-1

Gene Copy Number Variation


In COSMIC - Cell Lines Project cse3 has gain in 0 cell-lines, loss in 0 cell-lines and no signal in 0 cell-lines. (see details)

3D Structures


For cse3 there are:
7 structures (14 chains) solved
0 are solved in complex with at least one small molecule ligand



(see details)
Molecular Target 3D Synopsis