Molecular Target Synopsis
Overview
Domains and Structures
Drugs and Clinical Candidates
Druggability
Chemistry
Ligand Efficiency Plot
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hao1,hao2,hao3 (Q50925) - Overview - Molecular Target Synopsis

Protein


hao1,hao2,hao3, Hydroxylamine oxidoreductase
Enzyme Classification 1.7.2.6
UniProt Q50925

Also Known as HAO_NITEU, hao1,hao2,hao3

Catalyzes the oxidation of hydroxylamine to nitrite. The electrons released in the reaction are partitioned to ammonium monooxygenase and to the respiratory chain. The immediate acceptor of electrons from HAO is cytochrome c-554. Homotrimer.

4N4N
NITROSOMONAS EUROPEA HAO
RCSB/PDB
Inspect Structure
See all 3D Structures for hao1,hao2,hao3

Isoforms / Transcripts (Protein Coding)


Protein Length Ensembl Gene Ensembl Transcript Ensembl Protein Uniprot Isoform
570Q50925-1

Sub-cellular localization


UniProt: hao1,hao2,hao3 is active in the following subcellular-locations: periplasm.
GO terms: hao1,hao2,hao3 is active in the following subcellular-locations: periplasmic space.



UniProt
GO terms

Gene Copy Number Variation


In COSMIC - Cell Lines Project hao1,hao2,hao3 has gain in 0 cell-lines, loss in 0 cell-lines and no signal in 0 cell-lines. (see details)

3D Structures


For hao1,hao2,hao3 there are:
4 structures (11 chains) solved
4 are solved in complex with at least one small molecule ligand



(see details)
Molecular Target 3D Synopsis