Molecular Target Synopsis
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(Q4MV79) - Druggability - Molecular Target Synopsis

Chain-based assessment (last updated 08/10/2019)
Structural Druggability Help: Help

Chain-based assessment (last updated 08/10/2019)


Chains assessed5
Chains with at least one site assessed as druggable using the strict criteria5
Chains with at least one site assessed as druggable using the relaxed criteria5


		
PDB Chain Protein Name Druggable Relaxed Druggable Strict Details
4FXQ_A Putative ADP-ribosyltransferase Certhrax Yes Yes show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 1.92 68.4 41.4 Yes Yes
2 bound 2.12 72.1 39.9 No No
3 empty 1.95 62.6 46.7 No No
4 empty 1.99 67.1 29.6 No No
5 empty 2.32 67.4 10.8 No No
6 empty 1.73 64 14.6 No No
7 empty 1.82 68 11.7 No No
8 empty 2.13 69.3 19.5 No No
9 empty 2.28 67 9.8 No No
10 empty 2.42 68.1 12.3 No No
4GF1_A Putative ADP-ribosyltransferase Certhrax Yes Yes show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 1.87 68.9 42.8 Yes Yes
2 empty 1.65 67.3 34.5 No No
3 empty 1.71 68.9 38.8 No No
4 empty 1.52 57.7 25.3 No No
5 empty 2.06 69.1 18 No No
6 empty 1.94 67.8 12.7 No No
7 empty 1.49 70.3 13.8 No No
8 empty 1.63 80.7 11.7 No No
9 empty 2.16 71.8 12.4 No No
10 empty 2.43 53 11.3 No No
4GF1_B Putative ADP-ribosyltransferase Certhrax Yes Yes show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 2.07 68.2 37.7 Yes Yes
2 empty 2.21 64.8 28.1 No No
3 empty 1.9 68.2 24.3 No No
4 empty 2.12 67.7 36.1 No No
5 empty 1.98 71.3 27.7 No No
6 empty 2.26 56.1 29.1 No No
7 empty 2.27 66.9 18.8 No No
8 empty 2.13 65.9 17.6 No No
9 empty 1.64 69.9 11.6 No No
10 empty 2.25 61.3 20.9 No No
4FXQ_B Putative ADP-ribosyltransferase Certhrax Yes Yes show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 1.79 67.7 39 Yes Yes
2 bound 2.11 71.2 40.3 No No
3 empty 1.96 64.1 44.5 No No
4 empty 2.08 63.9 31.8 No No
5 empty 1.96 61.3 22.3 No No
6 empty 2.45 55.2 18.3 No No
7 empty 1.83 65.6 17.9 No No
8 empty 1.92 70.5 10.1 No No
9 empty 2.12 65 10.9 No No
10 empty 2.16 62.6 14.6 No No
4FK7_A Putative ADP-ribosyltransferase Certhrax Yes Yes show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 bound 2.4 70 34 Yes Yes
2 empty 2.3 58.5 27.9 No No
3 empty 2.4 62.4 19.3 No No
4 empty 2.28 59.7 16.5 No No
5 empty 2.43 63.6 17.8 No No
6 empty 2.53 61.3 11.3 No No
7 empty 2.82 50.6 10 No No
8 empty 1.43 80 7.9 No No
9 empty 2.86 61.6 8.1 No No
10 empty 1.82 65.8 7.1 No No
Ligand-based Druggability Score:
Ligand-based Druggability Score Percentile: %
Ligand-based Druggability Help: Help




		
This protein has no network-based druggability score