Molecular Target Synopsis
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(Q4KGU2) - Druggability - Molecular Target Synopsis

Chain-based assessment (last updated 23/07/2019)
Structural Druggability Help: Help

Chain-based assessment (last updated 23/07/2019)


Chains assessed4
Chains with at least one site assessed as druggable using the strict criteria0
Chains with at least one site assessed as druggable using the relaxed criteria4


		
PDB Chain Protein Name Druggable Relaxed Druggable Strict Details
4J9X_B 4-hydroxyproline 2-epimerase Yes No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 2.04 62.9 36.2 Yes No
2 empty 2.29 68.3 28.9 No No
3 empty 2.11 67.8 24 No No
4 empty 2.39 67.6 21 No No
5 empty 2.14 60.1 20 No No
6 empty 2.13 65.1 17.7 No No
7 empty 2.16 65.2 18.9 No No
8 empty 2.3 66.9 8.8 No No
9 empty 1.83 62.9 8.9 No No
10 empty 2.74 67.6 11 No No
4J9W_A 4-hydroxyproline 2-epimerase Yes No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 2.01 62.5 47.2 Yes No
2 empty 2.16 66.1 27.6 No No
3 empty 2.26 67.7 25.4 No No
4 bound 2.36 66.8 28.9 No No
5 empty 2.15 70.9 16.2 No No
6 empty 1.74 64.5 9.2 No No
7 empty 2.91 73.5 6.8 No No
8 empty 2.23 63.3 9.7 No No
9 empty 1.92 69.2 9.2 No No
10 bound .98 97.8 0 Yes No
4J9W_B 4-hydroxyproline 2-epimerase Yes No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 1.87 62 36.5 Yes No
2 empty 2.12 65.3 29 No No
3 empty 2.46 62 29.8 No No
4 empty 2.21 66.6 29.1 No No
5 bound 2.35 64.2 30.4 No No
6 empty 2.21 61.3 23.7 No No
7 empty 2.9 64.5 13.1 No No
8 empty 1.95 62.7 11 No No
9 empty 2.89 72.7 8.2 No No
10 empty 2.33 62 10.3 No No
4J9X_A 4-hydroxyproline 2-epimerase Yes No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 2.23 63.9 32.6 Yes No
2 empty 2.3 64.4 28 No No
3 empty 2.06 66 29.5 No No
4 empty 2.27 66.1 22.3 No No
5 empty 2.34 64.9 30.1 No No
6 empty 1.97 55.1 11.5 No No
7 empty 2.2 65 19.3 No No
8 empty 1.93 64 10.4 No No
9 empty 2.32 62.1 12.2 No No
10 empty 2.96 74.6 7.5 No No
Ligand-based Druggability Score:
Ligand-based Druggability Score Percentile: %
Ligand-based Druggability Help: Help




		
This protein has no network-based druggability score