Molecular Target Synopsis
Overview
Domains and Structures
Drugs and Clinical Candidates
Druggability
Chemistry
Ligand Efficiency Plot
Pathways
Family Cladogram
Interaction Network
Gene Expression
Gene Copy Number Variation
RNAi
Mutations
Germline Genetics

RABL6 (Q3YEC7) - Overview - Molecular Target Synopsis

Protein


RABL6, Rab-like protein 6
UniProt Q3YEC7

Also Known as RABL6_HUMAN, RABL6, C9orf86, PARF

May enhance cellular proliferation. May reduce growth inhibitory activity of CDKN2A.

Isoforms / Transcripts (Protein Coding)


Sub-cellular localization


UniProt: RABL6 is active in the following subcellular-locations: cytoplasm, nucleus.
GO terms: RABL6 is active in the following subcellular-locations: centrosome, cytoplasm, cytosol, nucleus.



UniProt
GO terms

Gene Copy Number Variation


In COSMIC - Cell Lines Project RABL6 has gain in 2 cell-lines, loss in 1 cell-lines and no signal in 1001 cell-lines. (see details)

Gene Expression


In NCI60, the highest expressing cell lines are:

In Array Express (RNA-seq of 675 commonly used human cancer cell lines), the highest expressing cell lines are: HCC515, 786-O, PE/CA-PJ15

In Array Express (RNA-seq of long poly adenylated RNA and long non poly adenylated RNA from ENCODE cell lines), the highest expressing cell lines are: SK-N-SH, K562, A549

(see details)