Molecular Target Synopsis
Overview
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Drugs and Clinical Candidates
Druggability
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Ligand Efficiency Plot
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(Q3V4T6) - Druggability - Molecular Target Synopsis

Chain-based assessment (last updated 23/04/2019)
Structural Druggability Help: Help

Chain-based assessment (last updated 23/04/2019)


Chains assessed3
Chains with at least one site assessed as druggable using the strict criteria0
Chains with at least one site assessed as druggable using the relaxed criteria3


		
PDB Chain Protein Name Druggable Relaxed Druggable Strict Details
4ART_A Structural protein ORF273 Yes No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 1.97 67.6 31.4 Yes No
2 bound 2.19 66.8 25.9 No No
3 bound 2.29 65.4 20.3 No No
4 empty 2.24 64.8 23.1 No No
5 empty 2.27 64 20 No No
6 empty 2.39 65.3 12.2 No No
7 empty 2.18 60.5 12.6 No No
8 empty 2.18 72 10.1 No No
9 empty 2.08 61.1 14.7 No No
10 empty 2.32 62.9 16.6 No No
4ATS_A Structural protein ORF273 Yes No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 1.89 67.4 29 Yes No
2 empty 2.37 66.3 25.4 No No
3 empty 2.17 67 20.1 No No
4 empty 2.32 62.9 22.4 No No
5 empty 2.09 57.1 20.7 No No
6 empty 2.16 62.9 13.6 No No
7 empty 2.17 65.9 11.8 No No
8 empty 2.1 62.2 14 No No
9 empty 2.34 64.7 9.3 No No
10 empty 2.46 65.4 10.6 No No
4ART_B Structural protein ORF273 Yes No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 1.87 62.7 24.8 Yes No
2 empty 2.31 62.2 21.6 No No
3 empty 2.01 64.2 18.6 No No
4 empty 2.12 69.9 14.4 No No
5 empty 2.2 60.5 15.8 No No
6 empty 1.85 56.7 14.4 No No
7 empty 1.81 63 11.8 No No
8 empty 2.34 55.3 12.1 No No
9 bound 2.21 57.1 12.4 No No
10 empty 1.82 55.8 10.4 No No
Ligand-based Druggability Score:
Ligand-based Druggability Score Percentile: %
Ligand-based Druggability Help: Help




		
This protein has no network-based druggability score