Molecular Target Synopsis
Overview
Domains and Structures
Drugs and Clinical Candidates
Druggability
Chemistry
Ligand Efficiency Plot
Pathways
Family Cladogram
Interaction Network
Gene Expression
Gene Copy Number Variation
RNAi
Mutations
Germline Genetics

ADCK5 (Q3MIX3) - Overview - Molecular Target Synopsis

Protein


ADCK5, Uncharacterized aarF domain-containing protein kinase 5
Enzyme Classification 2.7.11.-
UniProt Q3MIX3

Also Known as ADCK5_HUMAN, ADCK5

The function of this protein is not yet clear. It is not known if it has protein kinase activity and what type of substrate it would phosphorylate (Ser, Thr or Tyr).

Isoforms / Transcripts (Protein Coding)


Sub-cellular localization


UniProt: ADCK5 is active in the following subcellular-locations: membrane.
GO terms: ADCK5 is active in the following subcellular-locations: integral component of membrane.



UniProt
GO terms

Gene Copy Number Variation


In COSMIC - Cell Lines Project ADCK5 has gain in 12 cell-lines, loss in 2 cell-lines and no signal in 991 cell-lines. (see details)

Gene Expression


In NCI60, the highest expressing cell lines are: COLO205, HT29, NCI_ADR_RES

In Array Express (RNA-seq of 675 commonly used human cancer cell lines), the highest expressing cell lines are: SW 1463, SNU-216, NCI-H209

In Array Express (RNA-seq of long poly adenylated RNA and long non poly adenylated RNA from ENCODE cell lines), the highest expressing cell lines are: SK-N-SH, K562, HUVEC

(see details)