Molecular Target Synopsis
Overview
Domains and Structures
Drugs and Clinical Candidates
Druggability
Chemistry
Ligand Efficiency Plot
Pathways
Family Cladogram
Interaction Network
Gene Expression
Gene Copy Number Variation
RNAi
Mutations
Germline Genetics

NSUN5P1 (Q3KNT7) - Overview - Molecular Target Synopsis

Protein


NSUN5P1, Putative NOL1/NOP2/Sun domain family member 5B
Enzyme Classification 2.1.1.-
UniProt Q3KNT7

Also Known as NSN5B_HUMAN, NSUN5P1, NSUN5B, WBSCR20B

Isoforms / Transcripts (Protein Coding)


Protein Length Ensembl Gene Ensembl Transcript Ensembl Protein Uniprot Isoform
163Q3KNT7-1
154Q3KNT7-3
117Q3KNT7-2

Sub-cellular localization


GO terms: NSUN5P1 is active in the following subcellular-locations: nucleolus.



UniProt
GO terms

Gene Copy Number Variation


In COSMIC - Cell Lines Project NSUN5P1 has gain in 0 cell-lines, loss in 0 cell-lines and no signal in 0 cell-lines. (see details)

Gene Expression


In NCI60, the highest expressing cell lines are:

In Array Express (RNA-seq of 675 commonly used human cancer cell lines), the highest expressing cell lines are: SK-MM-2, MDA-MB-361, SW 620

In Array Express (RNA-seq of long poly adenylated RNA and long non poly adenylated RNA from ENCODE cell lines), the highest expressing cell lines are: SK-N-SH, K562, MCF-7

(see details)

3D Structures


At greater than 90% identity similarity to NSUN5P1 there are:
1 structures (1 chains) solved
1 are solved in complex with at least one small molecule ligand



(see details)
Molecular Target 3D Synopsis