Molecular Target Synopsis
Overview
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Drugs and Clinical Candidates
Druggability
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(Q1QU06) - Druggability - Molecular Target Synopsis

Chain-based assessment (last updated 03/09/2019)
Structural Druggability Help: Help

Chain-based assessment (last updated 03/09/2019)


Chains assessed2
Chains with at least one site assessed as druggable using the strict criteria2
Chains with at least one site assessed as druggable using the relaxed criteria2


		
PDB Chain Protein Name Druggable Relaxed Druggable Strict Details
4JCI_B 4-hydroxyproline 2-epimerase Yes Yes show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 1.85 76.8 23.3 Yes Yes
2 empty 2.26 66.4 30.3 No No
3 empty 2.08 62.1 22.9 No No
4 empty 2.55 64.7 20.9 No No
5 empty 2.23 66.3 24.7 No No
6 empty 2.41 53.5 16.6 No No
7 empty 1.7 73.8 11.5 No No
8 empty 2.5 63.9 16.6 No No
9 empty 1.95 63.4 15 No No
10 empty 2.55 67.5 11.8 No No
4JCI_A 4-hydroxyproline 2-epimerase Yes Yes show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 1.87 67.7 48.2 Yes Yes
2 empty 2.33 71.9 21.1 No No
3 empty 2.06 61.7 22.6 No No
4 empty 2.64 64 17.7 No No
5 empty 2.18 65.2 21.8 No No
6 empty 1.95 70.3 11.7 No No
7 empty 2.1 71.4 16.3 No No
8 empty 1.99 59.7 10.8 No No
9 empty 1.76 58.2 10.6 No No
10 empty 2.8 60.2 8.9 No No
Ligand-based Druggability Score:
Ligand-based Druggability Score Percentile: %
Ligand-based Druggability Help: Help




		
This protein has no network-based druggability score