Molecular Target Synopsis
Overview
Domains and Structures
Drugs and Clinical Candidates
Druggability
Chemistry
Ligand Efficiency Plot
Pathways
Family Cladogram
Interaction Network
Gene Expression
Gene Copy Number Variation
RNAi
Mutations
Germline Genetics

(Q1QU06) - Overview - Molecular Target Synopsis

Protein


, 4-hydroxyproline 2-epimerase
Enzyme Classification 5.1.1.8
UniProt Q1QU06

Also Known as 4HYPE_CHRSD

Catalyzes the epimerization of trans-4-hydroxy-L-proline (t4LHyp) to cis-4-hydroxy-D-proline (c4DHyp). Is likely involved in a degradation pathway that converts t4LHyp to alpha-ketoglutarate. Displays no proline racemase activity.

4JCI
CRYSTAL STRUCTURE OF CSAL_2705, A PUTATIVE HYDROXYPROLINE EPIMERASE FROM CHROMOHALOBACTER SALEXIGENS (TARGET EFI-506486), SPACE GROUP P212121, UNLIGANDED
RCSB/PDB
Inspect Structure
See all 3D Structures for

Isoforms / Transcripts (Protein Coding)


Protein Length Ensembl Gene Ensembl Transcript Ensembl Protein Uniprot Isoform
311Q1QU06-1

Gene Copy Number Variation


In COSMIC - Cell Lines Project has gain in 0 cell-lines, loss in 0 cell-lines and no signal in 0 cell-lines. (see details)

3D Structures


For there are:
1 structures (2 chains) solved
0 are solved in complex with at least one small molecule ligand



(see details)
Molecular Target 3D Synopsis