Molecular Target Synopsis
Overview
Domains and Structures
Drugs and Clinical Candidates
Druggability
Chemistry
Ligand Efficiency Plot
Pathways
Family Cladogram
Interaction Network
Gene Expression
Gene Copy Number Variation
RNAi
Mutations
Germline Genetics

dddP (Q166H0) - Overview - Molecular Target Synopsis

Protein


dddP, Dimethlysulfonioproprionate lyase DddP
Enzyme Classification 4.4.1.3
UniProt Q166H0

Also Known as DDDP_ROSDO, dddP

Able to cleave dimethlysulfonioproprionate (DMSP), releasing dimethyl sulfide (DMS). DMS is the principal form by which sulfur is transported from oceans to the atmosphere. The real activity of the protein is however subject to debate and it is unclear whether it constitutes a real dimethlysulfonioproprionate lyase in vivo: the low activity with DMSP as substrate suggests that DMSP is not its native substrate. Homodimer.

Isoforms / Transcripts (Protein Coding)


Protein Length Ensembl Gene Ensembl Transcript Ensembl Protein Uniprot Isoform
447Q166H0-1

Gene Copy Number Variation


In COSMIC - Cell Lines Project dddP has gain in 0 cell-lines, loss in 0 cell-lines and no signal in 0 cell-lines. (see details)

3D Structures


For dddP there are:
1 structures (1 chains) solved
0 are solved in complex with at least one small molecule ligand



(see details)
Molecular Target 3D Synopsis