Molecular Target Synopsis
Overview
Domains and Structures
Drugs and Clinical Candidates
Druggability
Chemistry
Ligand Efficiency Plot
Pathways
Family Cladogram
Interaction Network
Gene Expression
Gene Copy Number Variation
RNAi
Mutations
Germline Genetics

RHOH (Q15669) - Domains And Structures - Molecular Target Synopsis

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Structural Sequence Similarity Matches
Domains Covered Gene Name (Uniprot) Solved in Complex with Organism PDB Chain Identity E-Value Resolution Ligands Release Date
Ras family (96%) (view alignment) CDC42 (P60953) - HUMAN 1AN0_A 44.12 2.0E-39 2.8Å GDP 1999-01-13
Ras family (96%) (view alignment) CDC42 (P60953) ARHGAP1 (Q07960) HUMAN 1AM4_E 45.24 1.0E-39 2.7Å GNP 1998-07-15
Ras family (96%) (view alignment) CDC42 (P60953) WAS (P42768) HUMAN 1CEE_A 44.12 1.0E-39 GCP 1999-06-30
Ras family (95%) (view alignment) - BRAIN-EATING AMOEBA 5VCU_A 39.41 2.0E-32 1.85Å GDP 2017-05-03
Ras family (96%) (view alignment) RHOA (P61586) (Q8KNY0) HUMAN 4XSG_A 41.57 5.0E-36 1.8Å GSP 2015-06-24
Ras family (96%) (view alignment) RHOA (P61586) ARHGAP1 (Q07960) HUMAN 6R3V_B 42.17 4.0E-37 1.75Å GDP MES 2019-05-08
Ras family (96%) (view alignment) RAC1 (P63000), (O49003) - OAT, HUMAN 2WKR_A 42.51 8.0E-38 2.2Å GTP FMN 2009-08-18
Ras family (96%) (view alignment) Cdc42 (P60766) Diaph1 (O08808) MOUSE 3EG5_C 44.71 5.0E-40 2.7Å GNP 2008-10-14
Ras family (96%) (view alignment) CDC42 (P60953) Pak3 (Q61036) HUMAN 1EES_A 44.12 1.0E-39 - 2000-03-29
Ras family (96%) (view alignment) RHOA (P61586) ARHGDIA (P52565) HUMAN 1CC0_A 41.57 7.0E-36 4Å GDP 2000-01-07
Ras family (96%) (view alignment) CDC42 (P60953) DOCK7 (Q96N67) HUMAN 6AJ4_F 44.12 2.0E-39 3.256Å - 2019-03-20
Ras family (96%) (view alignment) RAC1 (P63000) - HUMAN 3TH5_B 42.86 8.0E-39 2.3Å GNP 2012-07-18
Ras family (96%) (view alignment) CDC42 (P60953) IQGAP2 (Q13576) HUMAN 5CJP_A 44.12 4.0E-39 2.57Å GTP 2016-08-10
Ras family (96%) (view alignment) RHOA (P61586) (Q8KNY0) HUMAN 5BWM_A 41.57 5.0E-36 2.5Å GDP 2015-06-24
Ras family (96%) (view alignment) RAC3 (P60763) PAK1 (Q13153) HUMAN 2QME_A 42.35 7.0E-39 1.75Å GCP 2007-08-28
Ras family (96%) (view alignment) RAC1 (P63000) Tiam1 (Q60610) HUMAN 1FOE_F 42.35 4.0E-39 2.8Å - 2001-01-17
Ras family (96%) (view alignment) RAC1 (P63000) - HUMAN 2P2L_B 42.11 3.0E-39 1.9Å GDP 2007-05-01
Ras family (96%) (view alignment) RAC2 (P15153) - HUMAN 2W2V_A 41.18 5.0E-38 1.95Å GTP 2009-05-05
Ras family (96%) (view alignment) CDC42 (P60953) - HUMAN 2QRZ_B 44.12 2.0E-39 2.4Å GCP 2008-03-18
Ras family (96%) (view alignment) RHOA (P61586) (Q8KNY0) HUMAN 4XSH_A 41.57 5.0E-36 2.3Å GSP 2015-06-24
Ras family (96%) (view alignment) CDC42 (P60953) Mcf2l (Q64096) HUMAN 1KZ7_B 44.12 1.0E-39 2.4Å - 2002-03-20
Ras family (96%) (view alignment) RAC1 (P63000) ARHGDIA (P52565) HUMAN 1HH4_A 42.86 9.0E-39 2.7Å GDP 2001-08-28
Ras family (96%) (view alignment) RAC1 (P63000) DOCK2 (Q92608) HUMAN 3B13_B 41.76 2.0E-38 3Å - 2012-03-14
Ras family (96%) (view alignment) RHO1 (P06780) SEC3 (P33332) BAKER'S YEAST 3A58_F 40.36 2.0E-31 2.6Å GNP 2010-01-12
Ras family (96%) (view alignment) RAC3 (P60763) PAK4 (O96013) HUMAN 2OV2_E 42.35 7.0E-39 2.1Å GCP 2007-03-13
Ras family (96%) (view alignment) ARAC7 (O82480) - MOUSE-EAR CRESS 2J0V_A 39.88 4.0E-33 1.78Å GDP 2006-10-04
Ras family (96%) (view alignment) RAC1 (P63000) ARHGEF28 (Q8N1W1) HUMAN 6BC1_B 42.86 7.0E-39 2.54Å GSP 2017-12-13
Ras family (96%) (view alignment) RAC1 (P63000) PREX1 (Q8TCU6) HUMAN 5FI0_D 42.11 4.0E-39 3.25Å - 2016-04-20
Ras family (96%) (view alignment) RAC1 (P63000) TRIO (O75962) HUMAN 2NZ8_A 42.35 4.0E-39 2Å - 2007-04-10
Ras family (96%) (view alignment) RHOA (P61586) ARHGEF11 (O15085) HUMAN 5JHG_F 42.17 4.0E-37 2.5Å - 2017-04-26
Ras family (96%) (view alignment) RHOA (P61586) ARHGDIA (P19803) HUMAN 5FR1_A 42.17 5.0E-37 2.75Å GDP 2016-01-13
Ras family (96%) (view alignment) CDC42 (P60953) Mcf2l (Q64096) HUMAN 1KZG_B 44.12 1.0E-39 2.6Å - 2002-03-20
Ras family (96%) (view alignment) CDC42 (P60953) ITSN1 (Q15811) HUMAN 3QBV_A 44.12 4.0E-39 2.65Å GDP 2012-02-08
Ras family (96%) (view alignment) RAC1 (P63000) - HUMAN 4GZM_A 42.26 4.0E-38 2.8Å GSP 2012-12-12
Ras family (96%) (view alignment) RAC2 (P15153) ARHGDIB (P52566) HUMAN 1DS6_A 41.18 2.0E-38 2.35Å GDP 2000-07-12
Ras family (96%) (view alignment) CDC42 (P60953) DOCK9 (Q9BZ29) HUMAN 2WMN_B 44.12 2.0E-39 2.39Å GDP 2009-09-22
Ras family (96%) (view alignment) CDC42 (P60953) DOCK7 (Q96N67) HUMAN 6AJL_F 44.12 2.0E-39 3.23Å - 2019-03-20
Ras family (96%) (view alignment) RAC2 (P15153) PLCG2 (P16885) HUMAN 2W2X_B 41.67 8.0E-38 2.3Å GSP 2009-05-05
Ras family (96%) (view alignment) RAC1 (P63000) ARHGEF28 (Q8N1W1) HUMAN 6BC1_A 42.86 7.0E-39 2.54Å GSP 2017-12-13
Ras family (96%) (view alignment) RHOA (P61586) ROCK1 (Q13464) HUMAN 1S1C_B 42.17 4.0E-37 2.6Å GNP 2004-02-10
Ras family (96%) (view alignment) RHOA (P61586) (Q9AJW7) HUMAN 3LWN_B 42.17 4.0E-37 2.28Å GDP 2010-03-31
Ras family (96%) (view alignment) RAC1 (P63000) PREX1 (Q8TCU6) HUMAN 5FI0_F 42.11 4.0E-39 3.25Å - 2016-04-20
Ras family (96%) (view alignment) CDC42 (P60953) PAK4 (O96013) HUMAN 5UPK_C 44.71 1.0E-39 2.4Å GNP 2017-12-27
Ras family (96%) (view alignment) CDC42 (P60953) ITSN1 (Q15811) HUMAN 3QBV_C 44.12 4.0E-39 2.65Å GDP 2012-02-08
Ras family (96%) (view alignment) ARAC5 (Q38937) ROPGEF8 (Q9LV40) THALE CRESS 2NTY_C 39.76 9.0E-34 3.1Å GDP 2007-01-23
Ras family (96%) (view alignment) CDC42 (P60953) TNK2 (Q07912) HUMAN 1CF4_A 44.12 3.0E-39 GNP 1999-06-18
Ras family (96%) (view alignment) RHOA (P61586) Arhgef18 (Q6P9R4) HUMAN 6BCB_F 42.17 4.0E-37 1.4Å GSP 2017-12-13
Ras family (96%) (view alignment) RHOA (P61586) ARHGDIA (P52565) HUMAN 1CC0_C 41.57 7.0E-36 4Å GDP 2000-01-07
Ras family (96%) (view alignment) ARAC7 (O82480) - MOUSE-EAR CRESS 2J0V_D 39.88 4.0E-33 1.78Å GDP 2006-10-04
Ras family (96%) (view alignment) CDC42 (P60953) - HUMAN 1A4R_A 44.12 2.0E-39 2.5Å GDP 1999-03-02
Ras family (96%) (view alignment) RAC3 (P60763) PAK4 (O96013) HUMAN 2OV2_G 42.35 7.0E-39 2.1Å GCP 2007-03-13
Ras family (96%) (view alignment) RAC2 (P15153) PLCG2 (P16885) HUMAN 2W2X_A 41.67 8.0E-38 2.3Å GSP 2009-05-05
Ras family (96%) (view alignment) (A0A068C8U8) - ASPERGILLUS FUMIGATUS 5ZVP_A 39.76 1.0E-31 1.4Å GDP 2019-05-15
Ras family (96%) (view alignment) RHOA (P61586) (Q9AJW7) HUMAN 3LW8_B 42.17 4.0E-37 1.85Å GDP 2010-03-31
Ras family (96%) (view alignment) RHOC (P08134) - HUMAN 2GCN_A 42.77 1.0E-37 1.85Å GDP 2007-03-27
Ras family (96%) (view alignment) RHOA (P61586) RAP1GDS1 (P52306) HUMAN 5ZHX_g 42.17 6.0E-37 3.5Å FAR 2018-09-05
Ras family (96%) (view alignment) CDC42 (P60953) DOCK7 (Q96N67) HUMAN 6AJ4_B 44.12 2.0E-39 3.256Å - 2019-03-20
Ras family (96%) (view alignment) RAC1 (P63000) sptP (P74873) HUMAN 1G4U_R 42.35 5.0E-39 2.3Å GDP 2001-01-24
Ras family (96%) (view alignment) CDC42 (P60953) ARHGAP1 (Q07960) HUMAN 2NGR_A 44.12 2.0E-39 1.9Å GDP 1999-01-06
Ras family (96%) (view alignment) RHOC (P08134) Diaph1 (O08808) HUMAN 1Z2C_C 42.17 2.0E-36 3Å GNP 2005-05-10
Ras family (96%) (view alignment) RHOA (P61586) ARHGAP1 (Q07960) HUMAN 5M6X_B 41.57 6.0E-36 2.4Å GDP 2017-05-17
Ras family (96%) (view alignment) CDC42 (P60953) ARHGAP1 (Q07960) HUMAN 1GRN_A 44.12 2.0E-39 1.8Å GDP 1999-12-22
Ras family (96%) (view alignment) RHOA (P61586) (Q9AJW7) HUMAN 3LW8_C 42.17 4.0E-37 1.85Å GDP 2010-03-31
Ras family (96%) (view alignment) RHOU (Q7L0Q8) - HUMAN 2Q3H_A 41.92 6.0E-36 1.73Å GDP 2007-06-19
Ras family (96%) (view alignment) CDC42 (P60953) sopE (O52623) 1GZS_A 44.12 2.0E-39 2.3Å - 2002-09-12
Ras family (96%) (view alignment) RHOA (P61586) (Q9AJW7) HUMAN 3LXR_A 42.17 4.0E-37 1.68Å GDP 2010-03-31
Ras family (96%) (view alignment) RHOA (P61586) MYO9B (Q13459) HUMAN 5HPY_B 41.57 6.0E-36 2.4Å GDP 2016-07-13
Ras family (96%) (view alignment) Rhoa (P61589) - RAT 3TVD_B 42.17 4.0E-37 2.989Å GSP 2012-10-10
Ras family (96%) (view alignment) RHOA (P61586) (Q9AJW7) HUMAN 3LW8_A 42.17 4.0E-37 1.85Å GDP 2010-03-31
Ras family (96%) (view alignment) RHOA (P61586) ARHGEF12 (Q9NZN5) HUMAN 1X86_F 42.17 5.0E-37 3.2Å - 2004-09-21
Ras family (96%) (view alignment) RHOA (P61586) ARHGAP20 (Q9P2F6) HUMAN 3MSX_A 41.57 5.0E-36 1.65Å GDP 2011-03-16
Ras family (96%) (view alignment) RHOA (P61586) Gnaq (P21279), Gnai1 (P10824), ARHGEF25 (Q86VW2) HUMAN 2RGN_F 42.17 5.0E-37 3.5Å - 2008-01-15
Ras family (96%) (view alignment) RAC1 (P63000) PLXNB1 (O43157) HUMAN 3SUA_A 42.35 4.0E-39 4.39Å GNP 2011-09-07
Ras family (96%) (view alignment) CDC42 (P60953) ibpA (Q06277) HUMAN 4ITR_D 44.12 2.0E-39 2.3Å GDP AMP 2013-02-20
Ras family (96%) (view alignment) RHOA (P61586) ARHGEF28 (Q8N1W1) HUMAN 6BC0_F 42.17 4.0E-37 2.198Å GSP 2017-12-13
Ras family (96%) (view alignment) RHOA (P61586) ARHGEF12 (Q9NZN5) HUMAN 1X86_H 42.17 5.0E-37 3.2Å - 2004-09-21
Ras family (96%) (view alignment) RAC1 (P63000) - HUMAN 3SBE_A 42.26 8.0E-38 2.6Å GNP 2012-07-18
Ras family (96%) (view alignment) RAC3 (P60763) PAK4 (O96013) HUMAN 2OV2_A 42.35 7.0E-39 2.1Å GCP 2007-03-13
Ras family (96%) (view alignment) CDC42 (P60953) FMNL1 (O95466) HUMAN 4YDH_D 44.71 7.0E-40 3.8Å GNP 2015-05-13
Ras family (96%) (view alignment) RHOA (P61586) ARHGAP1 (Q07960) HUMAN 5M70_B 41.57 6.0E-36 2.2Å GDP 2017-05-17
Ras family (96%) (view alignment) RHOA (P61586) ROCK1 (Q13464) HUMAN 1S1C_A 42.17 4.0E-37 2.6Å GNP 2004-02-10
Ras family (96%) (view alignment) RHOA (P61586) ARHGAP1 (Q07960) HUMAN 1OW3_B 41.57 6.0E-36 1.8Å GDP 2003-05-06
Ras family (96%) (view alignment) RAC1 (P63000), (O49003) - OAT, HUMAN 2WKQ_A 42.51 8.0E-38 1.6Å GTP FMN 2009-08-18
Ras family (96%) (view alignment) RAC3 (P60763) PAK4 (O96013) HUMAN 2OV2_B 42.35 7.0E-39 2.1Å GCP 2007-03-13
Ras family (96%) (view alignment) CDC42 (P60953) FMNL2 (Q96PY5) HUMAN 4YC7_A 44.71 7.0E-40 2.5Å GNP 2015-05-13
Ras family (96%) (view alignment) RHOA (P61586) ARHGEF12 (Q9NZN5) HUMAN 1X86_B 42.17 5.0E-37 3.2Å - 2004-09-21
Ras family (96%) (view alignment) RAC1 (P63000) DOCK2 (Q92608) HUMAN 3B13_D 41.76 2.0E-38 3Å - 2012-03-14
Ras family (96%) (view alignment) RAC1 (P63000) Vav1 (P27870) HUMAN 2VRW_A 42.35 4.0E-39 1.85Å - 2008-06-17
Ras family (96%) (view alignment) RAC1 (P63000) - HUMAN 5N6O_B 42.86 6.0E-39 2.586Å GDP 2017-12-27
Ras family (96%) (view alignment) CDC42 (P60953) ITSN1 (Q15811) HUMAN 1KI1_C 44.12 1.0E-39 2.3Å - 2002-05-29
Ras family (96%) (view alignment) RHOA (P61586) - HUMAN 1DPF_A 41.57 9.0E-36 1.9Å GDP 2000-06-21
Ras family (96%) (view alignment) CDC42 (P60953) DOCK7 (Q96N67) HUMAN 6AJ4_H 44.12 2.0E-39 3.256Å - 2019-03-20
Ras family (96%) (view alignment) RHOA (P61586) ARHGEF11 (O15085) HUMAN 3KZ1_F 42.17 4.0E-37 2.7Å GSP 2010-04-28
Ras family (96%) (view alignment) RHOA (P61586) Arhgap35 (P81128) HUMAN 5IRC_D 41.57 6.0E-36 1.72Å CSX GDP 2016-08-17
Ras family (96%) (view alignment) RHOQ (P17081) - HUMAN 2ATX_A 43.45 2.0E-36 2.65Å GNP 2005-09-13
Ras family (96%) (view alignment) CDC42 (P60953) FMNL1 (O95466) HUMAN 4YDH_B 44.71 7.0E-40 3.8Å GNP 2015-05-13
Ras family (96%) (view alignment) RHOA (P61586) ARHGEF11 (O15085) HUMAN 5JHH_F 42.17 4.0E-37 2.3Å RA0 2017-04-26
Ras family (96%) (view alignment) CDC42 (P60953) IQGAP2 (Q13576) HUMAN 5CJP_D 44.12 4.0E-39 2.57Å GTP 2016-08-10
Ras family (96%) (view alignment) CDC42 (P60953) ITSN1 (Q15811), (O49003) HUMAN 5HZK_A 44.71 6.0E-40 3.3Å GDP 2016-12-21
Ras family (96%) (view alignment) RAC3 (P60763) PAK4 (O96013) HUMAN 2OV2_D 42.35 7.0E-39 2.1Å GCP 2007-03-13
Ras family (95%) (view alignment) - BRAIN-EATING AMOEBA 5VCU_B 39.41 2.0E-32 1.85Å GDP 2017-05-03
Ras family (96%) (view alignment) CDC42 (P60953) Mcf2l (Q64096) HUMAN 1KZG_D 44.12 1.0E-39 2.6Å - 2002-03-20
Ras family (96%) (view alignment) RAC1 (P63000) ypkA (Q05608) HUMAN 2H7V_A 42.11 3.0E-39 2.6Å GDP 2006-09-19
Ras family (96%) (view alignment) RAC1 (P63000) VAV1 (P15498) HUMAN 3BJI_C 42.35 4.0E-39 2.6Å - 2008-07-15
Ras family (96%) (view alignment) RAC3 (P60763) - HUMAN 2C2H_B 42.35 7.0E-39 1.8Å GDP 2005-10-13
Ras family (96%) (view alignment) RAC1 (P63000) PREX1 (Q8TCU6) HUMAN 5FI0_B 42.11 4.0E-39 3.25Å - 2016-04-20
Ras family (96%) (view alignment) ARAP3 (Q8WWN8), RHOA (P61586) - HUMAN 5JCP_B 41.57 7.0E-36 2.1Å GDP 2016-06-22
Ras family (96%) (view alignment) CDC42 (P60953) - HUMAN 2KB0_A 43.53 5.0E-39 - 2009-12-01
Ras family (96%) (view alignment) RAC3 (P60763) - HUMAN 2G0N_B 42.35 7.0E-39 1.9Å GDP 2006-05-30
Ras family (96%) (view alignment) RAC2 (P15153) - HUMAN 2W2T_A 41.67 8.0E-38 1.95Å GDP 2009-05-05
Ras family (96%) (view alignment) RHOA (P61586) MYO9B (Q13459) HUMAN 5HPY_F 41.57 6.0E-36 2.4Å GDP 2016-07-13
Ras family (96%) (view alignment) CDC42 (P60953) Pard6b (Q9JK83) HUMAN 1NF3_B 44.12 5.0E-39 2.1Å GNP 2003-03-04
Ras family (96%) (view alignment) ARAC6 (Q9SBJ6) - THALE CRESS 3BWD_D 40.36 2.0E-34 1.53Å GDP 2008-03-11
Ras family (96%) (view alignment) RHOA (P61586) - HUMAN 1KMQ_A 41.57 2.0E-35 1.55Å GNP 2003-05-06
Ras family (96%) (view alignment) RAC1 (P63000) DOCK2 (Q92608) HUMAN 2YIN_D 42.35 3.0E-39 2.7Å - 2011-05-25
Ras family (96%) (view alignment) RHOA (P61586) - HUMAN 1FTN_A 41.57 6.0E-36 2.08Å GDP 1998-03-18
Ras family (96%) (view alignment) RAC1 (P63000) - HUMAN 1RYF_A 38.62 4.0E-36 1.75Å GDP 2004-01-27
Ras family (96%) (view alignment) RHOC (P08134) - HUMAN 2GCO_B 42.77 1.0E-37 1.4Å GNP 2007-03-27
Ras family (96%) (view alignment) CDC42 (P60953) - HUMAN 1A4R_B 44.12 2.0E-39 2.5Å GNH 1999-03-02
Ras family (96%) (view alignment) RAC2 (P15153) - HUMAN 2W2V_D 41.18 5.0E-38 1.95Å GTP 2009-05-05
Ras family (96%) (view alignment) RHOA (P61586) RAP1GDS1 (P52306) HUMAN 5ZHX_e 42.17 6.0E-37 3.5Å FAR 2018-09-05
Ras family (96%) (view alignment) CDC42 (P60953) ARHGAP1 (Q07960) HUMAN 1AM4_F 45.24 1.0E-39 2.7Å GNP 1998-07-15
Ras family (96%) (view alignment) RAC1 (P63000) PLCB2 (Q00722) HUMAN 2FJU_A 42.35 4.0E-39 2.2Å GSP 2006-11-21
Ras family (96%) (view alignment) RHOA (P61586) ARHGEF12 (Q9NZN5) HUMAN 1X86_D 42.17 5.0E-37 3.2Å - 2004-09-21
Ras family (96%) (view alignment) RAC1 (P63000) - HUMAN 1RYH_A 38.62 4.0E-36 1.75Å GNP 2004-01-27
Ras family (96%) (view alignment) CDC42 (P60953) DOCK7 (Q96N67) HUMAN 6AJ4_D 44.12 2.0E-39 3.256Å - 2019-03-20
Ras family (96%) (view alignment) RACGAP1 (Q9H0H5), RHOA (P61586) - HUMAN 5C2K_A 42.17 3.0E-37 1.42Å GDP 2016-06-22
Ras family (96%) (view alignment) RHOA (P61586) ARHGDIA (P19803) HUMAN 5FR2_A 42.17 5.0E-37 3.35Å FAR GDP 2016-01-13
Ras family (96%) (view alignment) RHOA (P61586) ARHGEF11 (O15085) HUMAN 3T06_B 41.57 6.0E-36 2.84Å - 2011-08-03
Ras family (96%) (view alignment) Rhoa (Q9QUI0) Arhgdia (Q99PT1) MOUSE 4F38_A 42.17 5.0E-37 2.8Å GNP GER 2012-05-23
Ras family (96%) (view alignment) RAC1 (P63000) ARFIP2 (P53365) HUMAN 1I4D_D 42.35 4.0E-39 2.5Å GDP 2001-05-16
Ras family (96%) (view alignment) CDC42 (P60953) ARHGAP1 (Q07960) HUMAN 1AM4_D 45.24 1.0E-39 2.7Å GNP 1998-07-15
Ras family (96%) (view alignment) RAC3 (P60763) PAK4 (O96013) HUMAN 2OV2_F 42.35 7.0E-39 2.1Å GCP 2007-03-13
Ras family (96%) (view alignment) RHOA (P61586) ARHGEF11 (O15085) HUMAN 5JHH_B 42.17 4.0E-37 2.3Å RA0 2017-04-26
Ras family (96%) (view alignment) RAC1 (P63000) - HUMAN 5N6O_A 42.86 6.0E-39 2.586Å GDP 2017-12-27
Ras family (96%) (view alignment) RHOA (P61586) ARHGAP1 (Q07960) HUMAN 5M70_G 41.57 6.0E-36 2.2Å GDP 2017-05-17
Ras family (96%) (view alignment) RHOA (P61586) ARHGEF11 (O15085) HUMAN 3T06_F 41.57 6.0E-36 2.84Å - 2011-08-03
Ras family (96%) (view alignment) RHO1 (P06780) SEC3 (P33332) BAKER'S YEAST 3A58_D 40.36 2.0E-31 2.6Å GNP 2010-01-12
Ras family (96%) (view alignment) CDC42 (P60953) DOCK9 (Q9BZ29) HUMAN 2WMO_B 44.12 2.0E-39 2.2Å GTP 2009-09-22
Ras family (96%) (view alignment) CDC42 (P60953) - HUMAN 2QRZ_A 44.12 2.0E-39 2.4Å GCP 2008-03-18
Ras family (96%) (view alignment) RAC1 (P63000) Plxna1 (P70206) HUMAN 3RYT_C 42.35 9.0E-39 3.58Å GNP 2012-01-18
Ras family (96%) (view alignment) RAC1 (P63000) NCF2 (P19878) HUMAN 1E96_A 42.86 1.0E-38 2.4Å GTP 2000-11-17
Ras family (96%) (view alignment) RHOA (P61586) ARHGEF11 (O15085) HUMAN 5JHG_B 42.17 4.0E-37 2.5Å - 2017-04-26
Ras family (96%) (view alignment) CDC42 (P60953) Mcf2l (Q64096) HUMAN 1KZ7_D 44.12 1.0E-39 2.4Å - 2002-03-20
Ras family (96%) (view alignment) RHOA (P61586) ANLN (Q9NQW6) HUMAN 4XOI_A 41.57 1.0E-35 2.09Å GTP 2015-07-15
Ras family (96%) (view alignment) CDC42 (P60953) PAK4 (O96013) HUMAN 5UPL_B 44.12 1.0E-39 3Å - 2017-12-27
Ras family (96%) (view alignment) RAC1 (P63000) - HUMAN 4GZL_B 42.86 2.0E-38 2Å GNP 2012-12-12
Ras family (96%) (view alignment) RAC1 (P63000) PREX1 (Q8TCU6) HUMAN 4YON_B 42.35 5.0E-39 1.95Å - 2015-07-01
Ras family (96%) (view alignment) RAC1 (P63000), (O49003) - OAT, HUMAN 2WKP_A 42.51 9.0E-38 1.9Å GTP FMN 2009-08-18
Ras family (96%) (view alignment) RHOA (P61586) ANLN (Q9NQW6) HUMAN 4XOI_C 41.57 1.0E-35 2.09Å GTP 2015-07-15
Ras family (96%) (view alignment) RAC1 (P63000) - HUMAN 4GZL_A 42.86 2.0E-38 2Å GNP 2012-12-12
Ras family (96%) (view alignment) RAC1 (P63000) - HUMAN 3TH5_A 42.86 8.0E-39 2.3Å GNP 2012-07-18
Ras family (96%) (view alignment) RAC1 (P63000) - HUMAN 1MH1_A 42.86 8.0E-39 1.38Å GNP 1998-01-21
Ras family (96%) (view alignment) RAC1 (P63000) VAV1 (P15498) HUMAN 3BJI_D 42.35 4.0E-39 2.6Å - 2008-07-15
Ras family (96%) (view alignment) CDC42 (P60953) sopB (O30916) HUMAN 4DID_A 44.12 1.0E-39 2.35Å GDP 2012-02-29
Ras family (96%) (view alignment) RHOC (P08134) - HUMAN 2GCO_A 42.77 1.0E-37 1.4Å CSX GNP 2007-03-27
Ras family (96%) (view alignment) RAC1 (P63000) PLXNB1 (O43157) HUMAN 3SUA_C 42.35 4.0E-39 4.39Å GNP 2011-09-07
Ras family (96%) (view alignment) RHOA (P61586) (Q9AJW7) HUMAN 3LWN_A 42.17 4.0E-37 2.28Å GDP 2010-03-31
Ras family (96%) (view alignment) RAC2 (P15153) - HUMAN 2W2V_B 41.18 5.0E-38 1.95Å GTP 2009-05-05
Ras family (96%) (view alignment) RHOA (P61586) ARHGEF11 (O15085) HUMAN 1XCG_B 41.57 6.0E-36 2.5Å - 2004-12-14
Ras family (96%) (view alignment) CDC42 (P60953) Dock8 (Q8C147) HUMAN 3VHL_B 43.53 9.0E-39 2.08Å - 2012-06-20
Ras family (96%) (view alignment) RHOA (P61586) Gnaq (P21279), Gnai1 (P10824), ARHGEF25 (Q86VW2) HUMAN 2RGN_C 42.17 5.0E-37 3.5Å - 2008-01-15
Ras family (96%) (view alignment) RHOA (P61586) ARHGAP1 (Q07960) HUMAN 1TX4_B 41.57 6.0E-36 1.65Å GDP 1998-09-16
Ras family (96%) (view alignment) RHOA (P61586) - HUMAN 5EZ6_B 42.17 4.0E-37 1.8Å GDP 2016-12-07
Ras family (96%) (view alignment) CDC42 (P60953) ARHGDIA (P19803) HUMAN 1DOA_A 44.12 2.0E-39 2.6Å GDP GER CMT 2000-02-09
Ras family (96%) (view alignment) CDC42 (P60953) Pak1 (P35465) HUMAN 1E0A_A 44.12 3.0E-39 GNP 2000-04-18
Ras family (96%) (view alignment) ARAC7 (O82480) - MOUSE-EAR CRESS 2J0V_B 39.88 4.0E-33 1.78Å GDP 2006-10-04
Ras family (96%) (view alignment) RAC1 (P63000) - HUMAN 2P2L_C 42.11 3.0E-39 1.9Å GDP 2007-05-01
Ras family (96%) (view alignment) RAC1 (P63000) - HUMAN 6AGP_A 41.18 1.0E-37 GDP 2019-03-20
Ras family (96%) (view alignment) RAC3 (P60763) - HUMAN 2C2H_A 42.35 7.0E-39 1.8Å GDP 2005-10-13
Ras family (96%) (view alignment) ARAC2 (Q38903) ROPGEF8 (Q9LV40) MOUSE-EAR CRESS 2WBL_D 40.61 3.0E-34 2.9Å - 2009-04-14
Ras family (96%) (view alignment) ARAC7 (O82480) - MOUSE-EAR CRESS 2J0V_C 39.88 4.0E-33 1.78Å GDP 2006-10-04
Ras family (96%) (view alignment) RAC1 (P63000) - HUMAN 2P2L_A 42.11 3.0E-39 1.9Å GDP 2007-05-01
Ras family (96%) (view alignment) RHOA (P61586) ARHGEF11 (O15085) HUMAN 3KZ1_E 42.17 4.0E-37 2.7Å GSP 2010-04-28
Ras family (96%) (view alignment) CDC42 (P60953) sopE (O52623) 1GZS_C 44.12 2.0E-39 2.3Å - 2002-09-12
Ras family (96%) (view alignment) ARAC5 (Q38937) ROPGEF8 (Q9LV40) THALE CRESS 2NTY_D 39.76 9.0E-34 3.1Å GDP 2007-01-23
Ras family (96%) (view alignment) RHOA (P61586) RAP1GDS1 (P52306) HUMAN 5ZHX_h 42.17 6.0E-37 3.5Å FAR 2018-09-05
Ras family (96%) (view alignment) CDC42 (P60953) (Q9R8E4) HUMAN 3GCG_A 44.64 3.0E-39 2.3Å - 2009-07-21
Ras family (96%) (view alignment) RAC1 (P63000) - HUMAN 3SBD_A 42.26 8.0E-38 2.1Å GNP 2012-07-18
Ras family (96%) (view alignment) RHOA (P61586) Mcf2l (Q64096) HUMAN 1LB1_D 42.17 5.0E-37 2.81Å - 2002-05-29
Ras family (96%) (view alignment) CDC42 (P60953) Arhgef9 (Q9QX73) HUMAN 2DFK_D 44.12 2.0E-39 2.15Å - 2006-05-02
Ras family (96%) (view alignment) RAC1 (P63000) ARHGDIA (P52565) HUMAN 1HH4_B 42.86 9.0E-39 2.7Å GDP 2001-08-28
Ras family (96%) (view alignment) CDC42 (P60953) DOCK7 (Q96N67) HUMAN 6AJL_H 44.12 2.0E-39 3.23Å - 2019-03-20
Ras family (96%) (view alignment) RHOA (P61586) Mcf2l (Q64096) HUMAN 1LB1_B 42.17 5.0E-37 2.81Å - 2002-05-29
Ras family (96%) (view alignment) CDC42 (P60953) IQGAP2 (Q13576) HUMAN 5CJP_B 44.12 4.0E-39 2.57Å GTP 2016-08-10
Ras family (96%) (view alignment) CDC42 (P60953) ITSN1 (Q15811) HUMAN 1KI1_A 44.12 1.0E-39 2.3Å - 2002-05-29
Ras family (96%) (view alignment) RHOC (P08134) Diaph1 (O08808) HUMAN 1Z2C_A 42.17 2.0E-36 3Å GNP 2005-05-10
Ras family (96%) (view alignment) RHOA (P61586) AKAP13 (Q12802) HUMAN 4D0N_A 42.17 5.0E-37 2.1Å GDP 2014-05-21
Ras family (96%) (view alignment) RHOB (P62745) - HUMAN 2FV8_A 42.77 9.0E-37 1.9Å GDP 2006-02-28
Ras family (96%) (view alignment) CDC42 (P60953) PAK6 (Q9NQU5) HUMAN 2ODB_A 44.12 1.0E-39 2.4Å GCP 2007-01-30
Ras family (96%) (view alignment) RAC1 (P63000) ARFIP2 (P53365) HUMAN 1I4L_D 42.35 4.0E-39 2.7Å GDP 2001-05-16
Ras family (96%) (view alignment) RAC1 (P63000) (Q51451) HUMAN 1HE1_D 42.86 7.0E-39 2Å GDP 2001-01-02
Ras family (96%) (view alignment) RAC1 (Q9SSX0) - RICE 4U5X_A 42.42 2.0E-34 1.9Å GNP 2014-08-20
Ras family (96%) (view alignment) RAC1 (P63000) PREX1 (Q8TCU6) HUMAN 5FI0_H 42.11 4.0E-39 3.25Å - 2016-04-20
Ras family (96%) (view alignment) RAC3 (P60763) - HUMAN 2IC5_A 42.35 7.0E-39 1.9Å BTB GNP 2006-10-10
Ras family (96%) (view alignment) CDC42 (P60953) - HUMAN 2ASE_A 43.53 7.0E-39 - 2006-02-21
Ras family (96%) (view alignment) ARAP3 (Q8WWN8), RHOA (P61586) - HUMAN 5JCP_A 41.57 7.0E-36 2.1Å GDP 2016-06-22
Ras family (96%) (view alignment) RAC1 (P63000) PLXNB1 (O43157) HUMAN 3SU8_A 42.35 4.0E-39 3.2Å GNP 2011-09-28
Ras family (96%) (view alignment) RHOA (P61586) PKN1 (Q16512) HUMAN 1CXZ_A 42.17 5.0E-37 2.2Å GSP 1999-10-08
Ras family (96%) (view alignment) RHOA (P61586) Mcf2l (Q64096) HUMAN 1LB1_H 42.17 5.0E-37 2.81Å - 2002-05-29
Ras family (96%) (view alignment) RHOA (P61586) - HUMAN 5A0F_A 42.17 4.0E-37 2Å NDG GDP 2015-07-22
Ras family (96%) (view alignment) RHOA (P61586) ARHGEF11 (O15085) HUMAN 1XCG_F 41.57 6.0E-36 2.5Å - 2004-12-14
Ras family (96%) (view alignment) RAC1 (P63000) (Q51451) HUMAN 1HE1_C 42.86 7.0E-39 2Å GDP 2001-01-02
Ras family (96%) (view alignment) RHOA (P61586) ARHGAP1 (Q07960) HUMAN 5M6X_I 41.57 6.0E-36 2.4Å GDP 2017-05-17
Ras family (96%) (view alignment) RHOC (P08134) - HUMAN 2GCP_A 42.77 1.0E-37 2.15Å GSP 2007-03-27
Ras family (96%) (view alignment) CDC42 (P60953) ITSN1 (Q15811), (O49003) HUMAN 5HZK_C 44.71 6.0E-40 3.3Å GDP 2016-12-21
Ras family (96%) (view alignment) CDC42 (P60953) ibpA (Q06277) HUMAN 4ITR_C 44.12 2.0E-39 2.3Å GDP AMP 2013-02-20
Ras family (96%) (view alignment) RAC1 (P63000) ypkA (Q05608) HUMAN 2H7V_B 42.11 3.0E-39 2.6Å GDP 2006-09-19
Ras family (96%) (view alignment) ARAC2 (Q38903) ROPGEF8 (Q9LV40) MOUSE-EAR CRESS 2WBL_C 40.61 3.0E-34 2.9Å - 2009-04-14
Ras family (96%) (view alignment) RHOA (P61586) AKAP13 (Q12802) HUMAN 6BCA_C 42.17 4.0E-37 1.995Å GSP 2017-12-13
Ras family (96%) (view alignment) RHOQ (P17081) - HUMAN 2ATX_B 43.45 2.0E-36 2.65Å GNP 2005-09-13
Ras family (96%) (view alignment) RAC1 (P63000) Tiam1 (Q60610) HUMAN 1FOE_B 42.35 4.0E-39 2.8Å - 2001-01-17
Ras family (96%) (view alignment) CDC42 (P60953) Arhgef9 (Q9QX73) HUMAN 2DFK_B 44.12 2.0E-39 2.15Å - 2006-05-02
Ras family (96%) (view alignment) CDC42 (P60953) - HUMAN 1AJE_A 44.12 2.0E-39 - 1997-11-12
Ras family (96%) (view alignment) RAC1 (P63000) - HUMAN 3SBD_B 42.26 8.0E-38 2.1Å GNP 2012-07-18
Ras family (96%) (view alignment) RHOA (P61586) NET1 (Q7Z628) HUMAN 4XH9_B 41.57 6.0E-36 2Å - 2015-01-14
Ras family (96%) (view alignment) RAC2 (P15153) - HUMAN 2W2V_C 41.18 5.0E-38 1.95Å GTP 2009-05-05
Ras family (96%) (view alignment) CDC42 (P60953) IQGAP2 (Q13576) HUMAN 5CJP_C 44.12 4.0E-39 2.57Å GTP 2016-08-10
Ras family (96%) (view alignment) Rhoa (P61589) - RAT 3TVD_A 42.17 4.0E-37 2.989Å GSP 2012-10-10
Ras family (96%) (view alignment) RAC1 (P63000) DOCK2 (Q92608) HUMAN 2YIN_C 42.35 3.0E-39 2.7Å - 2011-05-25
Ras family (96%) (view alignment) CDC42 (P60953) Pard6b (Q9JK83) HUMAN 1NF3_A 44.12 5.0E-39 2.1Å GNP 2003-03-04
Ras family (96%) (view alignment) CDC42 (P60953) DOCK9 (Q9BZ29) HUMAN 2WM9_B 44.12 2.0E-39 2.2Å - 2009-09-22
Ras family (96%) (view alignment) RAC1 (P63000) Tiam1 (Q60610) HUMAN 1FOE_D 42.35 4.0E-39 2.8Å - 2001-01-17
Ras family (96%) (view alignment) RHOA (P61586) Arhgap35 (P81128) HUMAN 5IRC_F 41.57 6.0E-36 1.72Å CSX GDP 2016-08-17
Ras family (96%) (view alignment) RHOA (P61586) (Q9AJW7) HUMAN 3LW8_D 42.17 4.0E-37 1.85Å GDP 2010-03-31
Ras family (96%) (view alignment) CDC42 (P60953) DOCK7 (Q96N67) HUMAN 6AJL_B 44.12 2.0E-39 3.23Å - 2019-03-20
Ras family (96%) (view alignment) RAC1 (P63000) PKN1 (Q16512) HUMAN 2RMK_A 42.35 8.0E-39 GCP 2007-11-13
Ras family (96%) (view alignment) RAC3 (P60763) PAK4 (O96013) HUMAN 2OV2_C 42.35 7.0E-39 2.1Å GCP 2007-03-13
Ras family (96%) (view alignment) RHOA (P61586) - HUMAN 1A2B_A 42.17 5.0E-37 2.4Å GSP 1998-06-17
Ras family (96%) (view alignment) RHOA (P61586) AKAP13 (Q12802) HUMAN 6BCA_F 42.17 4.0E-37 1.995Å GSP 2017-12-13
Ras family (96%) (view alignment) CDC42 (P60953) - HUMAN 1AN0_B 44.12 2.0E-39 2.8Å GDP 1999-01-13
Ras family (96%) (view alignment) CDC42 (P60953) BAIAP2 (Q9UQB8) HUMAN 4JS0_A 44.12 2.0E-39 1.9Å PE4 GNP 2014-03-05
Ras family (96%) (view alignment) RAC1 (P63000) Tiam1 (Q60610) HUMAN 1FOE_H 42.35 4.0E-39 2.8Å - 2001-01-17
Ras family (96%) (view alignment) RHOA (P61586) RAP1GDS1 (P52306) HUMAN 5ZHX_f 42.17 6.0E-37 3.5Å FAR 2018-09-05
Ras family (96%) (view alignment) RAC1 (P63000) Kalrn (P97924) HUMAN 5O33_A 42.35 4.0E-39 1.64Å GDP 2017-05-31
Ras family (96%) (view alignment) RHOA (P61586) - HUMAN 5C4M_A 41.57 6.0E-36 1.3Å GDP 2016-06-29
Ras family (96%) (view alignment) RAC3 (P60763) PAK4 (O96013) HUMAN 2OV2_H 42.35 7.0E-39 2.1Å GCP 2007-03-13
Ras family (96%) (view alignment) RAC1 (P63000) PLXNB1 (O43157) HUMAN 3SUA_B 42.35 4.0E-39 4.39Å GNP 2011-09-07
Ras family (96%) (view alignment) Cdc42 (P60766) Diaph1 (O08808) MOUSE 3EG5_A 44.71 5.0E-40 2.7Å GNP 2008-10-14
Ras family (96%) (view alignment) CDC42 (P60953) PREX1 (Q8TCU6) HUMAN 5FI1_B 43.86 2.0E-39 3.16Å - 2016-04-20
Ras family (96%) (view alignment) RHOA (P61586) Mcf2l (Q64096) HUMAN 1LB1_F 42.17 5.0E-37 2.81Å - 2002-05-29
Ras family (96%) (view alignment) RAC1 (P63000) - HUMAN 4GZM_B 42.26 4.0E-38 2.8Å GSP 2012-12-12
Ras family (96%) (view alignment) RHOA (P61586) NET1 (Q7Z628) HUMAN 4XH9_E 41.57 6.0E-36 2Å - 2015-01-14
Ras family (96%) (view alignment) RAC3 (P60763) - HUMAN 2IC5_B 42.35 7.0E-39 1.9Å GDP 2006-10-10
Ras family (96%) (view alignment) CDC42 (P60953) DOCK7 (Q96N67) HUMAN 6AJL_D 44.12 2.0E-39 3.23Å - 2019-03-20
Ras family (96%) (view alignment) RAC1 (P63000) ARFIP2 (P53365) HUMAN 1I4T_D 42.35 8.0E-39 2.6Å GNP 2001-05-16
Ras family (96%) (view alignment) RAC1 (P63000) - HUMAN 1RYH_B 38.62 4.0E-36 1.75Å GNP 2004-01-27
Ras family (96%) (view alignment) RAC3 (P60763) - HUMAN 2G0N_A 42.35 7.0E-39 1.9Å GDP 2006-05-30
Ras family (96%) (view alignment) Cdc42 (P60766) RACGAP1 (Q9H0H5) MOUSE 5C2J_B 44.12 2.0E-39 2.5Å GDP 2016-06-22
Ras family (96%) (view alignment) RAC1 (P63000) - HUMAN 1RYF_B 38.62 4.0E-36 1.75Å GDP 2004-01-27