Molecular Target Synopsis
Overview
Domains and Structures
Drugs and Clinical Candidates
Druggability
Chemistry
Ligand Efficiency Plot
Pathways
Family Cladogram
Interaction Network
Gene Expression
Gene Copy Number Variation
RNAi
Mutations
Germline Genetics

RHEB (Q15382) - Domains And Structures - Molecular Target Synopsis

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Structural Sequence Similarity Matches
Domains Covered Gene Name (Uniprot) Solved in Complex with Organism PDB Chain Identity E-Value Resolution Ligands Release Date
Ras family (100%) (view alignment) KRAS (P01116) - HUMAN 4L8G_A 37.04 3.0E-27 1.52Å GDP 2013-11-27
Ras family (94%) (view alignment) (F2UBE5) - 5WDS_A 36.42 1.0E-25 1.85Å GDP 2017-07-19
Ras family (100%) (view alignment) KRAS (P01116) - HUMAN 5VPZ_B 37.04 2.0E-27 1.85Å GSP 2017-12-06
Ras family (94%) (view alignment) KRAS (P01116) - HUMAN 5VQ8_B 37.09 7.0E-25 2.3Å GDP 2017-12-06
Ras family (97%) (view alignment) RAP1B (P61224) RASGRP2 (Q7LDG7) HUMAN 6AXF_D 41.61 2.0E-31 3.1Å - 2017-10-11
Ras family (100%) (view alignment) KRAS (P01116) - HUMAN 4LV6_A 37.65 1.0E-27 1.5Å 20H GDP 2013-11-27
Ras family (100%) (view alignment) KRAS (P01116) - HUMAN 6QUV_A 37.04 2.0E-27 1.47Å GCP 2019-07-31
Ras family (94%) (view alignment) KRAS (P01116) - 4PZY_B 37.09 5.0E-25 1.88Å GDP 2XR 2014-09-10
Ras family (99%) (view alignment) HRAS (P01112) - HUMAN 6E6C_A 36.48 2.0E-26 1.9Å GNP 2019-07-31
Ras family (100%) (view alignment) KRAS (P01116) - HUMAN 6ARK_A 37.65 1.0E-27 1.75Å GDP BQD 2018-01-31
Ras family (100%) (view alignment) KRAS (P01116) - HUMAN 6GJ5_B 37.04 2.0E-27 1.499Å GCP 2019-07-31
Ras family (100%) (view alignment) RHEB (Q15382) - HUMAN 5YXH_C 100 0 2.04Å GDP 2018-02-28
Ras family (97%) (view alignment) RAP1B (P61224) RAP1GAP (P47736) HUMAN 3BRW_D 41.61 2.0E-31 3.4Å GDP 2008-03-11
Ras family (91%) (view alignment) RAP2A (P10114) - HUMAN 2RAP_A 40.41 5.0E-25 2.5Å GTP 1998-06-17
Ras family (100%) (view alignment) KRAS (P01116) - HUMAN 4M1Y_C 37.65 1.0E-27 1.49Å GDP 2013-11-27
Ras family (97%) (view alignment) RAP1A (P62834) Apbb1ip (Q8R5A3) HUMAN 4KVG_C 42.24 1.0E-31 1.65Å GTP 2014-03-05
Ras family (100%) (view alignment) RHEB (Q15382) - HUMAN 3SEA_B 100 0 2Å GNP 2012-06-20
Ras family (100%) (view alignment) KRAS (P01116) - HUMAN 6E6F_A 37.04 3.0E-27 3Å GNP 2019-07-31
Ras family (100%) (view alignment) KRAS (P01116) - HUMAN 5V9U_B 37.65 1.0E-27 1.38Å GDP 91S 2018-02-07
Ras family (100%) (view alignment) RHEB (Q15382) - HUMAN 5YXH_A 100 0 2.04Å GDP 2018-02-28
Ras family (100%) (view alignment) KRAS (P01116) - HUMAN 4LYF_B 37.65 1.0E-27 1.568Å GDP 21C 2013-11-27
Ras family (99%) (view alignment) HRAS (P01112) - HUMAN 1AGP_A 36.48 1.0E-26 2.3Å GNP 1994-04-30
Ras family (99%) (view alignment) HRAS (P01112) - HUMAN 4L9W_A 36.48 1.0E-26 1.95Å GNP 2013-11-27
Ras family (94%) (view alignment) KRAS (P01116) - HUMAN 4EPX_A 37.09 7.0E-25 1.76Å GDP 0QR 2012-05-23
Ras family (100%) (view alignment) KRAS (P01116) - HUMAN 4M1S_C 37.65 1.0E-27 1.55Å GDP 2013-11-27
Ras family (99%) (view alignment) HRAS (P01112) - HUMAN 1PLL_A 36.48 2.0E-26 2.8Å GDP 1994-07-31
Ras family (97%) (view alignment) RAP1B (P61224) RASIP1 (Q5U651) HUMAN 5KHO_D 41.61 2.0E-31 2.78Å GNP 2016-10-19
Ras family (100%) (view alignment) RHEB (Q15382) - HUMAN 6BSX_A 100 0 1.65Å E7S GDP 2018-02-28
Ras family (100%) (view alignment) KRAS (P01116) - HUMAN 5VPY_B 37.04 2.0E-27 2Å 9GM 2017-12-06
Ras family (97%) (view alignment) RAP1A (P62834) RAF1 (P04049) HUMAN 3KUC_A 42.24 6.0E-32 1.92Å GDP 2010-03-23
Ras family (97%) (view alignment) RAP1B (P61224) Rapgef4 (Q9EQZ6) HUMAN 4MGI_R 41.61 2.0E-31 2.8Å - 2014-09-03
Ras family (100%) (view alignment) KRAS (P01116) - HUMAN 4M22_B 37.65 1.0E-27 2.09Å GDP 22C 2013-11-27
Ras family (100%) (view alignment) Rheb (Q921J2) - MOUSE 4O2R_B 98.82 1.0E-94 2.25Å GDP 2014-03-26
Ras family (94%) (view alignment) KRAS (P01116) - HUMAN 5VQ2_A 37.09 7.0E-25 1.96Å GTP 2017-12-06
Ras family (100%) (view alignment) KRAS (P01116) - HUMAN 4TQA_B 37.04 3.0E-27 1.13Å GDP 2015-06-10
Ras family (97%) (view alignment) RAP1B (P61224) Rapgef4 (Q9EQZ6) HUMAN 4MGZ_R 41.61 2.0E-31 3Å - 2014-09-03
Ras family (99%) (view alignment) HRAS (P01112) - HUMAN 821P_A 36.48 2.0E-26 1.5Å GNP 1994-01-31
Ras family (100%) (view alignment) KRAS (P01116) - HUMAN 4M1S_B 37.65 1.0E-27 1.55Å 21K GDP 2013-11-27
Ras family (100%) (view alignment) Rheb (Q921J2) - MOUSE 4O25_B 99.41 1.0E-95 2.2Å GTP 2014-03-26
Ras family (100%) (view alignment) Rheb (Q921J2) - MOUSE 4O25_A 99.41 1.0E-95 2.2Å GTP 2014-03-26
Ras family (100%) (view alignment) KRAS (P01116) - HUMAN 4TQA_A 37.04 3.0E-27 1.13Å GDP 2015-06-10
Ras family (100%) (view alignment) KRAS (P01116) - HUMAN 6GOF_A 37.04 2.0E-27 1.98Å GNP 2019-02-06
Ras family (100%) (view alignment) KRAS (P01116) - HUMAN 4LUC_B 37.65 1.0E-27 1.29Å 20G GDP 2013-11-27
Ras family (100%) (view alignment) KRAS (P01116) - HUMAN 4LYH_C 37.65 1.0E-27 1.37Å GDP 21F 2013-11-27
Ras family (97%) (view alignment) Rap1b (Q62636) - BROWN RAT,RAT,RATS 3X1Z_B 41.61 2.0E-31 1.25Å GNP 2015-06-03
Ras family (94%) (view alignment) KRAS (P01116) - HUMAN 4EPT_A 37.09 7.0E-25 2Å GDP 0QW 2012-05-23
Ras family (100%) (view alignment) RHEB (Q15382) - HUMAN 1XTQ_A 100 0 2Å GDP 2005-03-08
Ras family (97%) (view alignment) RAP1B (P61224) RASGRP2 (Q7LDG7) HUMAN 6AXF_H 41.61 2.0E-31 3.1Å - 2017-10-11
Ras family (99%) (view alignment) HRAS (P01112) - HUMAN 6DZH_C 36.48 2.0E-26 1.95Å GDP 2019-07-10
Ras family (100%) (view alignment) KRAS (P01116) - HUMAN 5V6V_B 37.65 1.0E-27 1.72Å GDP 8YA 2017-06-28
Ras family (100%) (view alignment) KRAS (P01116) - HUMAN 5USJ_F 37.04 3.0E-27 1.94Å GNP 2017-03-22
Ras family (97%) (view alignment) RAP1B (P61224) Rapgef4 (Q9EQZ6) HUMAN 4MH0_R 41.61 2.0E-31 2.4Å - 2014-09-03
Ras family (94%) (view alignment) KRAS (P01116) - HUMAN 5W22_B 37.09 7.0E-25 1.76Å GDP 2017-12-06
Ras family (97%) (view alignment) RAP1B (P61224) Rapgef4 (Q9EQZ6) HUMAN 4MGK_R 41.61 2.0E-31 2.7Å - 2014-09-03
Ras family (100%) (view alignment) KRAS (P01116) - HUMAN 5UFQ_A 37.04 3.0E-27 2.199Å GNP 2017-08-02
Ras family (100%) (view alignment) KRAS (P01116) SOS1 (Q07889) HUMAN 6EPN_R 37.04 3.0E-27 2.5Å - 2019-02-06
Ras family (97%) (view alignment) RAP1B (P61224) (Q5RGW1) HUMAN 4M8N_G 40.72 4.0E-32 3.29Å GDP 2013-10-09
Ras family (100%) (view alignment) KRAS (P01116) - HUMAN 6E6G_A 37.04 3.0E-27 1.93Å GDP 2019-07-31
Ras family (100%) (view alignment) KRAS (P01116) - HUMAN 4M1Y_A 37.65 1.0E-27 1.49Å GDP 2013-11-27
Ras family (94%) (view alignment) KRAS (P01116) - HUMAN 4EPV_A 37.09 7.0E-25 1.35Å 0QX GDP 2012-05-23
Ras family (100%) (view alignment) KRAS (P01116) - HUMAN 5VQ0_B 37.04 2.0E-27 2.3Å GDP 2017-12-06
Ras family (100%) (view alignment) KRAS (P01116) - HUMAN 5XCO_A 37.04 2.0E-27 1.25Å GDP 2017-05-24
Ras family (97%) (view alignment) DIRAS2 (Q96HU8) - HUMAN 2ERX_A 39.75 1.0E-28 1.65Å GDP 2005-11-01
Ras family (100%) (view alignment) KRAS (P01116) - HUMAN 5OCG_A 36.75 2.0E-27 1.45Å 9R5 GNP 2018-08-22
Ras family (100%) (view alignment) KRAS (P01116) - HUMAN 5VP7_F 37.04 2.0E-27 1.7Å GDP 2017-12-06
Ras family (97%) (view alignment) RAP1B (P61224) KRIT1 (O00522) HUMAN 4DXA_A 41.61 2.0E-31 1.95Å GSP 2012-05-16
Ras family (100%) (view alignment) KRAS (P01116) - HUMAN 6E6F_B 37.04 3.0E-27 3Å GNP 2019-07-31
Ras family (97%) (view alignment) RAP1B (P61224) RASGRP2 (Q7LDG7) HUMAN 6AXF_L 41.61 2.0E-31 3.1Å - 2017-10-11
Ras family (100%) (view alignment) KRAS (P01116) - HUMAN 5YXZ_A 37.65 1.0E-27 1.7Å 94C GDP 2018-04-18
Ras family (97%) (view alignment) RAP1B (P61224) RASIP1 (Q5U651) HUMAN 5KHO_C 41.61 2.0E-31 2.78Å GNP 2016-10-19
Ras family (100%) (view alignment) KRAS (P01116) - HUMAN 4M1W_C 37.65 1.0E-27 1.58Å GDP 21R 2013-11-27
Ras family (100%) (view alignment) KRAS (P01116) - HUMAN 4QL3_A 37.65 3.0E-28 1.04Å GDP 2015-06-10
Ras family (100%) (view alignment) KRAS (P01116) - HUMAN 4LYF_C 37.65 1.0E-27 1.568Å GDP 2013-11-27
Ras family (100%) (view alignment) KRAS (P01116) - HUMAN 4M1S_A 37.65 1.0E-27 1.55Å GDP 2013-11-27
Ras family (94%) (view alignment) KRAS (P01116) - HUMAN 5VQ6_A 37.09 7.0E-25 1.99Å GSP 2017-12-06
Ras family (94%) (view alignment) KRAS (P01116) - HUMAN 4EPW_A 37.09 7.0E-25 1.7Å 0QV GDP 2012-05-23
Ras family (97%) (view alignment) RAP1A (P62834) RAF1 (P04049) HUMAN 1C1Y_A 41.61 2.0E-31 1.9Å GTP 1999-08-02
Ras family (100%) (view alignment) KRAS (P01116) - HUMAN 4LV6_B 37.65 1.0E-27 1.5Å 20H GDP 2013-11-27
Ras family (100%) (view alignment) KRAS (P01116) - HUMAN 4LDJ_A 37.04 3.0E-27 1.15Å GDP 2014-06-04
Ras family (100%) (view alignment) KRAS (P01116) - HUMAN 5VPI_B 37.04 2.0E-27 1.62Å GTP 2017-12-06
Ras family (100%) (view alignment) RALA (P11233) Exoc2 (O54921) HUMAN 1UAD_B 35.12 3.0E-27 2.1Å GNP 2003-07-15
Ras family (100%) (view alignment) KRAS (P01116) - HUMAN 4M1O_B 37.65 1.0E-27 1.57Å GDP 21J 2013-11-27
Ras family (100%) (view alignment) KRAS (P01116) - HUMAN 4LYH_A 37.65 1.0E-27 1.37Å GDP 2013-11-27
Ras family (99%) (view alignment) HRAS (P01112) - HUMAN 1PLJ_A 36.48 2.0E-26 2.8Å CAG 1994-07-31
Ras family (100%) (view alignment) Rheb (Q921J2) - MOUSE 4O2L_A 98.82 3.0E-95 2.4Å GTP 2014-03-26
Ras family (100%) (view alignment) KRAS (P01116) - HUMAN 6MQG_A 36.42 5.0E-27 1.5Å GDP 2019-07-31
Ras family (100%) (view alignment) KRAS (P01116) - HUMAN 4DSN_A 36.75 2.0E-27 2.03Å GCP 2012-04-25
Ras family (100%) (view alignment) KRAS (P01116) - HUMAN 6B0V_B 37.65 1.0E-27 1.29Å GDP C8G 2018-05-16
Ras family (100%) (view alignment) KRAS (P01116) - HUMAN 4M1T_B 37.65 1.0E-27 1.7Å 21M GDP 2013-11-27
Ras family (100%) (view alignment) KRAS (P01116) - HUMAN 4M22_A 37.65 1.0E-27 2.09Å GDP 2013-11-27
Ras family (91%) (view alignment) RAP2A (P10114) - HUMAN 1KAO_A 40.41 5.0E-25 1.7Å GDP 1997-12-24
Ras family (100%) (view alignment) KRAS (P01116) - HUMAN 4M21_C 37.65 1.0E-27 1.94Å GDP 2013-11-27
Ras family (100%) (view alignment) RHEB (Q15382) - HUMAN 6BT0_A 100 0 1.78Å GDP 2018-02-28
Ras family (100%) (view alignment) KRAS (P01116) - HUMAN 5V71_D 37.04 3.0E-27 2.23Å 8ZG GDP 2017-08-23
Ras family (100%) (view alignment) KRAS (P01116) - HUMAN 5US4_A 37.04 3.0E-27 1.83Å GDP 2017-03-22
Ras family (100%) (view alignment) RALA (P11233) C3 (P15879) HUMAN 2BOV_A 35.54 2.0E-27 2.66Å GDP 2005-04-15
Ras family (100%) (view alignment) KRAS (P01116) - HUMAN 6QUV_B 37.04 2.0E-27 1.47Å GCP 2019-07-31
Ras family (100%) (view alignment) RHEB (Q15382) - HUMAN 3SEA_A 100 0 2Å GDP 2012-06-20
Ras family (99%) (view alignment) HRAS (P01112) - HUMAN 6E6P_B 36.48 2.0E-26 1.93Å GNP 2019-07-31
Ras family (94%) (view alignment) KRAS (P01116) - HUMAN 5VQ8_A 37.09 7.0E-25 2.3Å GDP 2017-12-06
Ras family (100%) (view alignment) RHEB (Q15382) - HUMAN 6BSX_B 100 0 1.65Å E7S GDP 2018-02-28
Ras family (100%) (view alignment) KRAS (P01116) - HUMAN 5V6S_A 37.65 1.0E-27 1.7Å 8YD GDP 2017-06-28
Ras family (99%) (view alignment) HRAS (P01112) - HUMAN 4L9S_A 36.48 1.0E-26 1.606Å GDP 2013-11-27
Ras family (100%) (view alignment) KRAS (P01116) - HUMAN 5KYK_C 37.04 3.0E-27 2.65Å 6ZD 2017-04-12
Ras family (94%) (view alignment) (F2UBE5) - 5WDR_A 36.42 1.0E-25 1.6Å GNP 2017-07-19
Ras family (100%) (view alignment) RALA (P11233) Exoc2 (O54921) HUMAN 1UAD_A 35.12 3.0E-27 2.1Å GNP 2003-07-15
Ras family (100%) (view alignment) KRAS (P01116) - HUMAN 5V71_F 37.04 3.0E-27 2.23Å 8ZG GDP 2017-08-23
Ras family (100%) (view alignment) KRAS (P01116) - HUMAN 6GJ6_A 37.04 2.0E-27 1.76Å GCP 2019-07-31
Ras family (100%) (view alignment) KRAS (P01116) - HUMAN 5V9L_B 37.04 3.0E-27 1.98Å GDP 91D 2017-08-23
Ras family (100%) (view alignment) KRAS (P01116) - HUMAN 6QUU_B 37.04 3.0E-27 1.47Å GCP 2019-07-31
Ras family (94%) (view alignment) KRAS (P01116) - HUMAN 5VQ2_B 37.09 7.0E-25 1.96Å GTP 2017-12-06
Ras family (100%) (view alignment) KRAS (P01116) - HUMAN 5KYK_A 37.04 3.0E-27 2.65Å 6ZD 2017-04-12
Ras family (100%) (view alignment) KRAS (P01116) - HUMAN 5VPI_A 37.04 2.0E-27 1.62Å GTP 2017-12-06
Ras family (99%) (view alignment) HRAS (P01112) - HUMAN 1PLK_A 36.48 2.0E-26 2.8Å GTP 1994-07-31
Ras family (100%) (view alignment) KRAS (P01116) - HUMAN 6N2J_A 37.65 1.0E-27 1.8Å K9M GDP 2018-12-12
Ras family (100%) (view alignment) KRAS (P01116) - HUMAN 4M1W_A 37.65 1.0E-27 1.58Å GDP 21R 2013-11-27
Ras family (90%) (view alignment) Rap1b (Q62636) - BROWN RAT,RAT,RATS 3X1Y_A 41.33 2.0E-28 1.168Å GNP 2015-06-03
Ras family (100%) (view alignment) KRAS (P01116) - HUMAN 6QUX_A 37.04 2.0E-27 1.6Å GCP 2019-07-31
Ras family (91%) (view alignment) RAP2A (P10114) - HUMAN 3RAP_S 40.41 5.0E-25 2.2Å GTP 1999-12-08
Ras family (100%) (view alignment) KRAS (P01116) - HUMAN 5USJ_D 37.04 3.0E-27 1.94Å GNP 2017-03-22
Ras family (83%) (view alignment) RRAS2 (P62070) - HUMAN 2ERY_B 39.85 2.0E-25 1.7Å GDP 2005-11-08
Ras family (97%) (view alignment) RAP1B (P61224) RASGRP2 (Q7LDG7) HUMAN 6AXF_P 41.61 2.0E-31 3.1Å - 2017-10-11
Ras family (100%) (view alignment) KRAS (P01116) - HUMAN 5YY1_A 37.65 1.0E-27 1.69Å 94F GDP 2018-04-18
Ras family (100%) (view alignment) RHEB (Q15382) - HUMAN 5YXH_D 100 0 2.04Å GDP 2018-02-28
Ras family (97%) (view alignment) RAP1B (P61224) RASGRP2 (Q7LDG7) HUMAN 6AXF_F 41.61 2.0E-31 3.1Å - 2017-10-11
Ras family (100%) (view alignment) RHEB (Q15382) - HUMAN 1XTS_A 100 0 2.8Å GTP 2005-03-08
Ras family (94%) (view alignment) (F2UBE5) - 5WDS_B 36.42 1.0E-25 1.85Å GDP 2017-07-19
Ras family (100%) (view alignment) KRAS (P01116) - HUMAN 4EPR_A 37.04 2.0E-27 2Å GDP 2012-05-23
Ras family (99%) (view alignment) HRAS (P01112) - HUMAN 6DZH_B 36.48 2.0E-26 1.95Å GDP 2019-07-10
Ras family (100%) (view alignment) KRAS (P01116) - HUMAN 5VPZ_A 37.04 2.0E-27 1.85Å GSP 2017-12-06
Ras family (100%) (view alignment) Rheb (Q921J2) - MOUSE 4O2R_A 98.82 1.0E-94 2.25Å GDP 2014-03-26
Ras family (100%) (view alignment) KRAS (P01116) - HUMAN 5VQ0_A 37.04 2.0E-27 2.3Å GDP 2017-12-06
Ras family (94%) (view alignment) (F2UBE5) - 5WDR_B 36.42 1.0E-25 1.6Å GNP 2017-07-19
Ras family (100%) (view alignment) KRAS (P01116) - HUMAN 5VPY_A 37.04 2.0E-27 2Å 9GM 2017-12-06
Ras family (100%) (view alignment) KRAS (P01116) - HUMAN 6GJ5_A 37.04 2.0E-27 1.499Å GCP 2019-07-31
Ras family (100%) (view alignment) KRAS (P01116) - HUMAN 4DST_A 36.75 2.0E-27 2.3Å 9LI GCP 2012-04-04
Ras family (100%) (view alignment) RHEB (Q15382) PDE6D (O43924) HUMAN 3T5G_A 100 0 1.7Å FAR GDP CMT 2011-10-26
Ras family (100%) (view alignment) KRAS (P01116) - HUMAN 4NMM_A 37.04 3.0E-27 1.89Å Y9Z 2014-06-04
Ras family (100%) (view alignment) KRAS (P01116) - HUMAN 4M1T_A 37.65 1.0E-27 1.7Å GDP 2013-11-27
Ras family (100%) (view alignment) RHEB (Q15382) - HUMAN 5YXH_B 100 0 2.04Å GDP 2018-02-28
Ras family (100%) (view alignment) KRAS (P01116) - HUMAN 4LRW_B 37.65 1.0E-27 2.15Å GDP 2013-11-27
Ras family (100%) (view alignment) KRAS (P01116) - HUMAN 4M22_C 37.65 1.0E-27 2.09Å GDP 22C 2013-11-27
Ras family (97%) (view alignment) RAP1B (P61224) (Q5RGW1) HUMAN 4M8N_H 40.72 4.0E-32 3.29Å GDP 2013-10-09
Ras family (100%) (view alignment) RHEB (Q15382) - HUMAN 1XTR_A 100 0 2.65Å GNP 2005-03-08
Ras family (100%) (view alignment) KRAS (P01116) - HUMAN 6MQN_C 36.42 5.0E-27 1.6Å GDP 2019-07-31
Ras family (100%) (view alignment) RHEB (Q15382) - HUMAN 6BSX_D 100 0 1.65Å E7S GDP 2018-02-28
Ras family (97%) (view alignment) RAP1B (P61224) Tln1 (P26039) HUMAN 6BA6_B 41.61 3.0E-31 - 2017-12-06
Ras family (99%) (view alignment) HRAS (P01112) - HUMAN 1JAI_A 36.48 2.0E-26 1.8Å GCP 1997-07-23
Ras family (100%) (view alignment) KRAS (P01116) - HUMAN 5USJ_B 37.04 3.0E-27 1.94Å GNP 2017-03-22
Ras family (100%) (view alignment) RALA (P11233) C3 (P15879) HUMAN 2A9K_A 35.12 3.0E-27 1.73Å GDP 2005-10-11
Ras family (100%) (view alignment) KRAS (P01116) - HUMAN 4M21_B 37.65 1.0E-27 1.94Å 21Y GDP 2013-11-27
Ras family (100%) (view alignment) KRAS (P01116) - HUMAN 6QUW_B 37.04 2.0E-27 1.24Å GCP 2019-07-31
Ras family (100%) (view alignment) KRAS (P01116) - HUMAN 4LYF_A 37.65 1.0E-27 1.568Å GDP 2013-11-27
Ras family (100%) (view alignment) KRAS (P01116) - HUMAN 5V71_B 37.04 3.0E-27 2.23Å 8ZG GDP 2017-08-23
Ras family (100%) (view alignment) KRAS (P01116) - HUMAN 5V9U_A 37.65 1.0E-27 1.38Å GDP 91S 2018-02-07
Ras family (100%) (view alignment) KRAS (P01116) - HUMAN 6GJ8_A 37.04 3.0E-27 1.65Å GCP 2019-07-31
Ras family (99%) (view alignment) NRAS (P01111) - HUMAN 6E6H_A 36.48 2.0E-26 2Å GNP 2019-07-31
Ras family (100%) (view alignment) RALA (P11233) C3 (P15879) HUMAN 2A78_A 35.12 3.0E-27 1.8Å GDP 2005-10-11
Ras family (97%) (view alignment) RAP1B (P61224) - HUMAN 3CF6_R 41.61 2.0E-31 2.2Å - 2008-07-29
Ras family (100%) (view alignment) KRAS (P01116) - HUMAN 4LYJ_A 37.65 1.0E-27 1.93Å GDP 21F 2013-11-27
Ras family (97%) (view alignment) RAP1B (P61224) (Q5RGW1) HUMAN 4M8N_F 40.72 4.0E-32 3.29Å GDP 2013-10-09
Ras family (97%) (view alignment) Rap1b (Q62636) - BROWN RAT,RAT,RATS 3X1X_A 41.61 2.0E-31 1Å GNP 2015-06-03
Ras family (99%) (view alignment) HRAS (P01112) - HUMAN 1CLU_A 36.48 2.0E-26 1.7Å DBG 1999-05-28
Ras family (100%) (view alignment) KRAS (P01116) - HUMAN 6MQN_A 36.42 5.0E-27 1.6Å GDP 2019-07-31
Ras family (99%) (view alignment) HRAS (P01112) - HUMAN 6E6P_C 36.48 2.0E-26 1.93Å GNP 2019-07-31
Ras family (100%) (view alignment) KRAS (P01116) - HUMAN 6B0V_A 37.65 1.0E-27 1.29Å GDP C8G 2018-05-16
Ras family (100%) (view alignment) KRAS (P01116) - HUMAN 4M1W_B 37.65 1.0E-27 1.58Å GDP 21R 2013-11-27
Ras family (94%) (view alignment) KRAS (P01116) - 4PZY_A 37.09 5.0E-25 1.88Å GDP 2014-09-10
Ras family (100%) (view alignment) KRAS (P01116) - HUMAN 5V6V_A 37.65 1.0E-27 1.72Å GDP 8YA 2017-06-28
Ras family (100%) (view alignment) KRAS (P01116) - HUMAN 5F2E_A 37.65 1.0E-27 1.4Å GDP 5UT 2016-01-13
Ras family (100%) (view alignment) KRAS (P01116) - HUMAN 4LRW_A 37.65 1.0E-27 2.15Å GDP 2013-11-27
Ras family (100%) (view alignment) KRAS (P01116) - HUMAN 4M1Y_B 37.65 1.0E-27 1.49Å GDP 21S 2013-11-27
Ras family (94%) (view alignment) KRAS (P01116) - HUMAN 5VBM_A 37.75 2.0E-25 1.49Å GDP 92V 2017-10-25
Ras family (100%) (view alignment) KRAS (P01116) - HUMAN 4DSU_A 36.75 2.0E-27 1.7Å BZI GDP 2012-04-04
Ras family (94%) (view alignment) KRAS (P01116) - HUMAN 5W22_A 37.09 7.0E-25 1.76Å GDP 2017-12-06
Ras family (99%) (view alignment) HRAS (P01112) - HUMAN 6E6P_A 36.48 2.0E-26 1.93Å GNP 2019-07-31
Ras family (100%) (view alignment) KRAS (P01116) - HUMAN 6QUW_A 37.04 2.0E-27 1.24Å GCP 2019-07-31
Ras family (100%) (view alignment) KRAS (P01116) - HUMAN 6B0Y_B 37.65 1.0E-27 1.43Å 8ZG GDP 2018-05-16
Ras family (100%) (view alignment) KRAS (P01116) - HUMAN 5UFQ_B 37.04 3.0E-27 2.199Å GNP 2017-08-02
Ras family (100%) (view alignment) KRAS (P01116) - HUMAN 6B0Y_A 37.65 1.0E-27 1.43Å 8ZG GDP 2018-05-16
Ras family (100%) (view alignment) KRAS (P01116) - HUMAN 6N2K_A 37.65 1.0E-27 1.72Å K9J GDP 2018-12-12
Ras family (100%) (view alignment) KRAS (P01116) SOS1 (Q07889) HUMAN 6EPM_R 37.04 3.0E-27 2.5Å - 2019-02-06
Ras family (97%) (view alignment) RAP1A (P62834) RAF1 (P04049) HUMAN 1GUA_A 42.24 6.0E-32 2Å GNP 1997-01-11
Ras family (100%) (view alignment) KRAS (P01116) SOS1 (Q07889) HUMAN 6EPO_R 37.04 3.0E-27 2.4Å - 2019-02-06
Ras family (97%) (view alignment) RAP1B (P61224) RASGRP2 (Q7LDG7) HUMAN 6AXF_B 41.61 2.0E-31 3.1Å - 2017-10-11
Ras family (97%) (view alignment) DIRAS2 (Q96HU8) - HUMAN 2ERX_B 39.75 1.0E-28 1.65Å GDP 2005-11-01
Ras family (100%) (view alignment) KRAS (P01116) - HUMAN 5USJ_C 37.04 3.0E-27 1.94Å GNP 2017-03-22
Ras family (94%) (view alignment) KRAS (P01116) - HUMAN 5VQ6_B 37.09 7.0E-25 1.99Å GSP 2017-12-06
Ras family (100%) (view alignment) KRAS (P01116) - HUMAN 4M1T_C 37.65 1.0E-27 1.7Å GDP 2013-11-27
Ras family (97%) (view alignment) RAP1B (P61224) Rapgef4 (Q9EQZ6) HUMAN 4MGY_R 41.61 2.0E-31 2.6Å - 2014-09-03
Ras family (97%) (view alignment) RAP1B (P61224) RASGRP2 (Q7LDG7) HUMAN 6AXF_J 41.61 2.0E-31 3.1Å - 2017-10-11
Ras family (94%) (view alignment) KRAS (P01116) - HUMAN 4EPY_A 37.09 7.0E-25 1.8Å 0QY GDP 2012-05-23
Ras family (99%) (view alignment) HRAS (P01112) - HUMAN 6DZH_A 36.48 2.0E-26 1.95Å GDP 2019-07-10
Ras family (100%) (view alignment) KRAS (P01116) SOS1 (Q07889) HUMAN 6EPP_R 37.04 3.0E-27 2.4Å - 2019-02-06
Ras family (100%) (view alignment) KRAS (P01116) - HUMAN 6MQN_B 36.42 5.0E-27 1.6Å GDP 2019-07-31
Ras family (100%) (view alignment) KRAS (P01116) - HUMAN 4M1O_A 37.65 1.0E-27 1.57Å GDP 2013-11-27
Ras family (100%) (view alignment) KRAS (P01116) - HUMAN 5V9O_A 37.04 3.0E-27 1.56Å GDP 91G 2017-08-23
Ras family (100%) (view alignment) KRAS (P01116) - HUMAN 5V71_A 37.04 3.0E-27 2.23Å 8ZG GDP 2017-08-23
Ras family (100%) (view alignment) KRAS (P01116) - HUMAN 4LYH_B 37.65 1.0E-27 1.37Å GDP 21F 2013-11-27
Ras family (100%) (view alignment) KRAS (P01116) - HUMAN 5VP7_A 37.04 2.0E-27 1.7Å GDP PGE 2017-12-06
Ras family (100%) (view alignment) Rheb (Q62639) - BROWN RAT,RAT,RATS 2L0X_A 99.41 1.0E-95 GDP 2010-08-04
Ras family (100%) (view alignment) KRAS (P01116) - HUMAN 5KYK_B 37.04 3.0E-27 2.65Å 6ZD 2017-04-12
Ras family (99%) (view alignment) HRAS (P01112) - HUMAN 1JAH_A 36.48 2.0E-26 1.8Å GCP 1997-07-23
Ras family (100%) (view alignment) KRAS (P01116) - HUMAN 5USJ_E 37.04 3.0E-27 1.94Å GNP 2017-03-22
Ras family (100%) (view alignment) KRAS (P01116) - HUMAN 5V9L_A 37.04 3.0E-27 1.98Å GDP 91D 2017-08-23
Ras family (100%) (view alignment) KRAS (P01116) - HUMAN 6QUX_B 37.04 2.0E-27 1.6Å GCP 2019-07-31
Ras family (83%) (view alignment) RRAS2 (P62070) - HUMAN 2ERY_A 39.85 2.0E-25 1.7Å GDP 2005-11-08
Ras family (100%) (view alignment) KRAS (P01116) - HUMAN 4DSO_A 36.75 2.0E-27 1.85Å BEN GSP 2012-04-04
Ras family (100%) (view alignment) KRAS (P01116) SOS1 (Q07889) HUMAN 6EPL_R 37.04 3.0E-27 2.55Å - 2019-02-06
Ras family (100%) (view alignment) KRAS (P01116) - HUMAN 4LUC_A 37.65 1.0E-27 1.29Å 20G GDP 2013-11-27
Ras family (100%) (view alignment) Rheb (Q921J2) - MOUSE 4O2L_B 98.82 3.0E-95 2.4Å GTP TRS 2014-03-26
Ras family (97%) (view alignment) RAP1B (P61224) (Q5RGW1) HUMAN 4M8N_E 40.72 4.0E-32 3.29Å GDP 2013-10-09
Ras family (100%) (view alignment) KRAS (P01116) - HUMAN 4M1O_C 37.65 1.0E-27 1.57Å GDP 2013-11-27
Ras family (97%) (view alignment) RAP1B (P61224) HEG1 (Q9ULI3), KRIT1 (O00522) HUMAN 4HDQ_B 41.61 2.0E-31 1.95Å GNP 2013-07-10
Ras family (100%) (view alignment) RHEB (Q15382) - HUMAN 6BSX_C 100 0 1.65Å E7S GDP 2018-02-28
Ras family (100%) (view alignment) KRAS (P01116) - HUMAN 6QUU_A 37.04 3.0E-27 1.47Å GCP 2019-07-31
Ras family (100%) (view alignment) RHEB (Q15382) - HUMAN 6BT0_D 100 0 1.78Å GDP 2018-02-28
Ras family (100%) (view alignment) RHEBL1 (Q8TAI7) - HUMAN 3OES_A 52.17 4.0E-54 2.3Å GNP 2010-08-25
Ras family (100%) (view alignment) KRAS (P01116) - HUMAN 5US4_B 37.04 3.0E-27 1.83Å GDP 2017-03-22
Ras family (100%) (view alignment) KRAS (P01116) - HUMAN 5V71_C 37.04 3.0E-27 2.23Å 8ZG GDP 2017-08-23
Ras family (100%) (view alignment) KRAS (P01116) - HUMAN 5V71_E 37.04 3.0E-27 2.23Å 8ZG GDP 2017-08-23
Ras family (97%) (view alignment) RAP1B (P61224) RASGRP2 (Q7LDG7) HUMAN 6AXF_N 41.61 2.0E-31 3.1Å - 2017-10-11
Ras family (100%) (view alignment) KRAS (P01116) - HUMAN 6GJ7_A 37.04 2.0E-27 1.67Å GCP 2019-07-31
Ras family (97%) (view alignment) Rap1b (Q62636) - BROWN RAT,RAT,RATS 3X1Z_A 41.61 2.0E-31 1.25Å GNP 2015-06-03
Ras family (97%) (view alignment) RAP1A (P62834) Apbb1ip (Q8R5A3) HUMAN 4KVG_A 42.24 1.0E-31 1.65Å GTP 2014-03-05
Ras family (97%) (view alignment) Rap1b (Q62636) - BROWN RAT,RAT,RATS 3X1W_A 41.61 2.0E-31 1.2Å GDP 2015-06-03
Ras family (100%) (view alignment) RHEB (Q15382) - HUMAN 6BT0_B 100 0 1.78Å E7V GDP 2018-02-28
Ras family (100%) (view alignment) RHEB (Q15382) - HUMAN 6BT0_C 100 0 1.78Å GDP 2018-02-28
Ras family (99%) (view alignment) HRAS (P01112) - HUMAN 421P_A 37.11 2.0E-27 2.2Å GNP 1994-01-31
Ras family (100%) (view alignment) KRAS (P01116) - HUMAN 4M21_A 37.65 1.0E-27 1.94Å GDP 2013-11-27
Ras family (97%) (view alignment) RAP1B (P61224) KRIT1 (O00522) HUMAN 4HDO_B 41.61 2.0E-31 1.67Å GNP 2013-07-10
Ras family (100%) (view alignment) KRAS (P01116) - HUMAN 5V9L_C 37.04 3.0E-27 1.98Å GDP 91D 2017-08-23
Ras family (91%) (view alignment) RAP2A (P10114) - HUMAN 3RAP_R 40.41 5.0E-25 2.2Å GTP 1999-12-08
Ras family (100%) (view alignment) KRAS (P01116) - HUMAN 5USJ_A 37.04 3.0E-27 1.94Å GNP 2017-03-22