Molecular Target Synopsis
Overview
Domains and Structures
Drugs and Clinical Candidates
Druggability
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Ligand Efficiency Plot
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ARFRP1 (Q13795) - Domains And Structures - Molecular Target Synopsis

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Structural Sequence Similarity Matches
Domains Covered Gene Name (Uniprot) Solved in Complex with Organism PDB Chain Identity E-Value Resolution Ligands Release Date
ADP-ribosylation factor family (92%) (view alignment) ARL5A (Q9Y689) - HUMAN 2H16_B 39.88 2.0E-29 2Å GDP 2006-06-13
ADP-ribosylation factor family (100%) (view alignment) ARL3 (A8ISN6) ARL13 (A8INQ0) 5DI3_A 40.64 9.0E-31 2.5Å GNP 2015-11-18
ADP-ribosylation factor family (93%) (view alignment) Arl3 (Q9WUL7) RP2 (O75695) HOUSE MOUSE 3BH7_A 40.94 2.0E-26 1.9Å GDP 2008-03-25
ADP-ribosylation factor family (100%) (view alignment) Arl3 (Q9WUL7) Cfap36 (Q8C6E0) HOUSE MOUSE 4ZI2_A 41.08 5.0E-27 2.2Å GNP 2015-11-11
ADP-ribosylation factor family (99%) (view alignment) ARL5A (Q9Y689) - HUMAN 1Z6Y_A 38.04 1.0E-30 2.4Å GDP 2005-04-05
ADP-ribosylation factor family (100%) (view alignment) Arl3 (Q9WUL7) - HOUSE MOUSE 1FZQ_A 41.08 5.0E-27 1.7Å GDP MES 2000-12-06
ADP-ribosylation factor family (93%) (view alignment) ARF1 (P11076) BCH1 (Q05029) BAKER'S YEAST 4Q66_L 35.06 2.0E-24 3.35Å GNP 2014-09-17
ADP-ribosylation factor family (92%) (view alignment) ARL5A (Q9Y689) - HUMAN 2H16_C 39.88 2.0E-29 2Å GDP 2006-06-13
ADP-ribosylation factor family (92%) (view alignment) ARL5A (Q9Y689) - HUMAN 2H17_A 39.88 3.0E-29 1.7Å GDP 2006-06-13
ADP-ribosylation factor family (99%) (view alignment) ARL2 (P36404) ARL2BP (Q9Y2Y0) HUMAN 3DOE_A 35.36 2.0E-27 2.25Å GTP 2009-03-03
ADP-ribosylation factor family (100%) (view alignment) Arl3 (Q9WUL7) UNC119 (Q13432) MOUSE 4GOJ_B 41.08 5.0E-27 2.1Å GNP 2012-09-19
ADP-ribosylation factor family (99%) (view alignment) ARL5A (Q9Y689) - HUMAN 1Z6Y_B 38.04 1.0E-30 2.4Å GDP 2005-04-05
ADP-ribosylation factor family (94%) (view alignment) ARL5B (Q96KC2) - HUMAN 1YZG_A 37.79 6.0E-28 2Å GDP 2005-03-22
ADP-ribosylation factor family (100%) (view alignment) Arl3 (Q9WUL7) Cfap36 (Q8C6E0) HOUSE MOUSE 4ZI3_B 41.08 5.0E-27 2Å GNP 2016-03-23
ADP-ribosylation factor family (97%) (view alignment) ARF2 (P19146) - BAKER'S YEAST 1MR3_F 35.36 3.0E-26 1.6Å G3D 2002-11-20
ADP-ribosylation factor family (100%) (view alignment) Arl3 (Q9WUL7) Cfap36 (Q8C6E0) HOUSE MOUSE 4ZI2_B 41.08 5.0E-27 2.2Å GNP 2015-11-11
ADP-ribosylation factor family (92%) (view alignment) ARL5A (Q9Y689) - HUMAN 2H16_A 39.88 2.0E-29 2Å GDP 2006-06-13
ADP-ribosylation factor family (100%) (view alignment) Arl3 (Q9WUL7) UNC119 (Q13432) MOUSE 4GOJ_A 41.08 5.0E-27 2.1Å GNP 2012-09-19
ADP-ribosylation factor family (100%) (view alignment) Arl3 (Q9WUL7) Cfap36 (Q8C6E0) HOUSE MOUSE 4ZI3_A 41.08 5.0E-27 2Å GNP 2016-03-23
ADP-ribosylation factor family (93%) (view alignment) ARF1 (P11076) BCH1 (Q05029) BAKER'S YEAST 4Q66_F 35.06 2.0E-24 3.35Å GNP 2014-09-17
ADP-ribosylation factor family (93%) (view alignment) ARF1 (P11076) BCH1 (Q05029) BAKER'S YEAST 4Q66_I 35.06 2.0E-24 3.35Å GNP 2014-09-17
ADP-ribosylation factor family (93%) (view alignment) Arl3 (Q9WUL7) RP2 (O75695) HOUSE MOUSE 3BH6_A 40.35 2.0E-25 2.6Å GNP 2008-03-25
ADP-ribosylation factor family (92%) (view alignment) ARL5A (Q9Y689) - HUMAN 2H16_D 39.88 2.0E-29 2Å GDP 2006-06-13
ADP-ribosylation factor family (99%) (view alignment) ARL2 (P36404) ARL2BP (Q9Y2Y0) HUMAN 3DOF_A 35.36 2.0E-27 3.3Å GTP 2009-03-03
ADP-ribosylation factor family (100%) (view alignment) Arl2 (Q9D0J4) PDE6D (O43924) HOUSE MOUSE 1KSG_A 35.11 1.0E-27 2.3Å GTP 2002-05-08
ADP-ribosylation factor family (97%) (view alignment) ARF1 (P11076) - RAT 2K5U_A 35.36 1.0E-26 GDP 2009-01-27
ADP-ribosylation factor family (100%) (view alignment) Arl2 (Q9D0J4) PDE6D (O43924) HOUSE MOUSE 1KSH_A 35.11 1.0E-27 1.8Å GDP 2002-05-08
ADP-ribosylation factor family (100%) (view alignment) Arl2 (Q9D0J4) PDE6D (O43924) HOUSE MOUSE 1KSJ_A 35.11 1.0E-27 2.6Å GTP GDP 2002-05-08
ADP-ribosylation factor family (90%) (view alignment) ARF1 (P11076) COPG1 (P53620), COPZ1 (P35604) BAKER'S YEAST 3TJZ_A 35.93 9.0E-25 2.9Å GNP 2012-02-22
ADP-ribosylation factor family (92%) (view alignment) ARL3 (A8ISN6) - 5DE3_A 42.26 6.0E-30 1.4Å GNP 2016-09-14
ADP-ribosylation factor family (99%) (view alignment) ARL5A (Q9Y689) - HUMAN 1ZJ6_A 38.04 1.0E-30 2Å G3D 2005-06-07
ADP-ribosylation factor family (90%) (view alignment) ARF1 (P11076) COPG1 (P53620), COPZ1 (P35604) BAKER'S YEAST 3TJZ_D 35.93 9.0E-25 2.9Å GNP 2012-02-22
ADP-ribosylation factor family (93%) (view alignment) ARF1 (P11076) BCH1 (Q05029) BAKER'S YEAST 4Q66_C 35.06 2.0E-24 3.35Å GNP 2014-09-17
ADP-ribosylation factor family (99%) (view alignment) ARF1 (P11076) - YEAST 2KSQ_A 35.14 2.0E-27 GTP MTN 2010-07-07