Molecular Target Synopsis
Overview
Domains and Structures
Drugs and Clinical Candidates
Druggability
Chemistry
Ligand Efficiency Plot
Pathways
Family Cladogram
Interaction Network
Gene Expression
Gene Copy Number Variation
RNAi
Mutations
Germline Genetics

BAG1 (Q0WUQ1) - Overview - Molecular Target Synopsis

Protein


BAG1, BAG family molecular chaperone regulator 1
UniProt Q0WUQ1

Also Known as BAG1_ARATH, BAG1

Co-chaperone that regulates diverse cellular pathways, such as programmed cell death and stress responses. Binds to the ATPase domain of HSP70/HSC70 chaperones.

4HWC
STRUCTURE OF ATBAG1
RCSB/PDB
Inspect Structure
See all 3D Structures for BAG1

Isoforms / Transcripts (Protein Coding)


Protein Length Ensembl Gene Ensembl Transcript Ensembl Protein Uniprot Isoform
342Q0WUQ1-1

Sub-cellular localization


GO terms: BAG1 is active in the following subcellular-locations: cytosol, mitochondrion, nucleus.



UniProt
GO terms

Gene Copy Number Variation


In COSMIC - Cell Lines Project BAG1 has gain in 0 cell-lines, loss in 0 cell-lines and no signal in 0 cell-lines. (see details)

3D Structures


For BAG1 there are:
2 structures (7 chains) solved
0 are solved in complex with at least one small molecule ligand



(see details)
Molecular Target 3D Synopsis