ADCY1 (Q08828) - Overview - Molecular Target Synopsis
ADCY1, Adenylate cyclase type 1
Enzyme Classification 126.96.36.199
Also Known as ADCY1_HUMAN, ADCY1
Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. Mediates responses to increased cellular Ca(2+)/calmodulin levels (By similarity). May be involved in regulatory processes in the central nervous system. May play a role in memory and learning. Plays a role in the regulation of the circadian rhythm of daytime contrast sensitivity probably by modulating the rhythmic synthesis of cyclic AMP in the retina. Interacts with CALM.
|Protein Length||Ensembl Gene||Ensembl Transcript||Ensembl Protein||Uniprot Isoform|
UniProt: ADCY1 is active in the following subcellular-locations: cell membrane, cytoplasm, membrane, membrane raft.
GO terms: ADCY1 is active in the following subcellular-locations: cytoplasm, extracellular exosome, glutamatergic synapse, hippocampal mossy fiber to CA3 synapse, integral component of plasma membrane, integral component of postsynaptic density membrane, membrane raft, nucleus, plasma membrane, Schaffer collateral - CA1 synapse.