Molecular Target Synopsis
Overview
Domains and Structures
Drugs and Clinical Candidates
Druggability
Chemistry
Ligand Efficiency Plot
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Interaction Network
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RNAi
Mutations
Germline Genetics

CDK18 (Q07002) - Domains And Structures - Molecular Target Synopsis

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Structural Sequence Similarity Matches
Domains Covered Gene Name (Uniprot) Solved in Complex with Organism PDB Chain Identity E-Value Resolution Ligands Release Date
Protein kinase domain (100%) (view alignment) CDK2 (P24941) - HUMAN 4FKT_A 53.2 1.0E-84 1.59Å 48K 2013-05-08
Protein kinase domain (100%) (view alignment) CDK2 (P24941) CCNA2 (P20248) HUMAN 1OIU_C 53.16 2.0E-85 2Å N76 2004-07-13
Protein kinase domain (100%) (view alignment) CDK2 (P24941) CCNA2 (P20248) HUMAN 4CFN_A 53.16 2.0E-85 2.2Å JYM 2013-12-18
Protein kinase domain (100%) (view alignment) CDK2 (P24941) CCNA2 (P20248) HUMAN 4EOM_A 52.67 6.0E-85 2.1Å ATP 2013-02-06
Protein kinase domain (100%) (view alignment) CDK2 (P24941) - HUMAN 5OSJ_A 53 2.0E-85 1.83Å AAK 2018-03-14
Protein kinase domain (100%) (view alignment) CDK2 (P24941) CCNA2 (P30274) HUMAN 3BHT_C 53.18 3.0E-85 2Å MFR 2008-02-12
Protein kinase domain (100%) (view alignment) CDK2 (P24941) CCNA2 (P20248) HUMAN 1OIY_C 53.16 2.0E-85 2.4Å N41 2004-07-13
Protein kinase domain (100%) (view alignment) CDK2 (P24941) CCNA2 (P20248) HUMAN 4CFW_A 53 2.0E-85 2.45Å SQ9 2013-12-18
Protein kinase domain (100%) (view alignment) CDK1 (P06493) CKS1B (P61024) HUMAN 4YC6_A 50.67 3.0E-86 2.6Å - 2015-05-20
Protein kinase domain (100%) (view alignment) CDK2 (P24941) CCNA2 (P20248) HUMAN 5IF1_C 53.2 1.0E-84 2.61Å - 2016-04-27
Protein kinase domain (100%) (view alignment) CDK2 (P24941) CCNA2 (P20248) HUMAN 4EOJ_A 53 4.0E-85 1.65Å ATP 2013-02-06
Protein kinase domain (100%) (view alignment) CDK2 (P24941) CCNA2 (P20248) HUMAN 4EOM_C 52.67 6.0E-85 2.1Å ATP 2013-02-06
Protein kinase domain (100%) (view alignment) CDK2 (P24941) CCNA2 (P20248) HUMAN 2IW9_C 53.16 3.0E-85 2Å 4SP 2006-09-06
Protein kinase domain (100%) (view alignment) CDK2 (P24941) - HUMAN 5FP5_A 53.2 1.0E-84 2.16Å 1Y6 2015-12-09
Protein kinase domain (100%) (view alignment) CDK2 (P24941) CCNA2 (P20248) 2WMB_C 53 2.0E-85 2.5Å - 2010-09-01
Protein kinase domain (100%) (view alignment) CDK2 (P24941) CCNA2 (P30274) HUMAN 3BHU_C 53.18 3.0E-85 2.3Å MHR 2008-02-12
Protein kinase domain (100%) (view alignment) CDK1 (P06493) CKS2 (P33552), CCNB1 (P14635) HUMAN 4YC3_A 50.5 6.0E-87 2.7Å - 2016-04-20
Protein kinase domain (100%) (view alignment) CDK2 (P24941) CDKN1B (P46527), CCNA2 (P20248) HUMAN 1H27_A 53 2.0E-85 2.2Å - 2003-02-01
Protein kinase domain (100%) (view alignment) CDK2 (P24941) - HUMAN 2VTS_A 53.2 1.0E-84 1.9Å LZC 2008-08-05
Protein kinase domain (100%) (view alignment) CDK2 (P24941) CCNA2 (P30274) HUMAN 6GUC_A 53.16 2.0E-85 2Å SU9 2018-12-05
Protein kinase domain (100%) (view alignment) CDK2 (P24941) CCNA2 (P20248) HUMAN 2IW8_A 53.16 7.0E-86 2.3Å 4SP 2006-09-06
Protein kinase domain (100%) (view alignment) CDK2 (P24941) CCNA2 (P20248) HUMAN 2WEV_A 53.2 1.0E-84 2.3Å CK7 2009-06-09
Protein kinase domain (100%) (view alignment) CDK2 (P24941) - HUMAN 4RJ3_A 53.2 1.0E-84 1.63Å 3QS ALY 2014-11-26
Protein kinase domain (100%) (view alignment) CDK2 (P24941) CCNA2 (P20248) HUMAN 2X1N_A 53.2 1.0E-84 2.75Å X1N 2010-02-16
Protein kinase domain (100%) (view alignment) CDK2 (P24941) - HUMAN 2VTQ_A 53.2 1.0E-84 1.9Å LZA 2008-08-05
Protein kinase domain (100%) (view alignment) CDK2 (P24941) CCNA2 (P20248) HUMAN 2WFY_C 53.2 1.0E-84 2.53Å - 2009-06-09
Protein kinase domain (100%) (view alignment) CDK2 (P24941) CCNA2 (P20248) 2WMA_C 53 2.0E-85 2.8Å - 2010-09-01
Protein kinase domain (100%) (view alignment) CDK2 (P24941) CCNA2 (P30274) HUMAN 4BCQ_A 53.18 3.0E-85 2.19Å TJF 2013-01-09
Protein kinase domain (100%) (view alignment) CDK2 (P24941) CCNA2 (P30274) HUMAN 3BHT_A 53.18 3.0E-85 2Å MFR 2008-02-12
Protein kinase domain (100%) (view alignment) CDK2 (P24941) CCNA2 (P20248) HUMAN 1H1S_C 53 2.0E-85 2Å 4SP 2002-09-19
Protein kinase domain (100%) (view alignment) CDK2 (P24941) Ccna2 (P51943) HUMAN 4II5_C 53.2 1.0E-84 2.15Å ADP 2013-01-23
Protein kinase domain (100%) (view alignment) CDK2 (P24941) Ccna2 (P51943) HUMAN 3QHW_C 53.18 5.0E-85 1.908Å ADP 2011-05-25
Protein kinase domain (100%) (view alignment) CDK5 (Q00535) CDK5R1 (Q15078) HUMAN 1UNL_A 56.6 2.0E-89 2.2Å RRC 2004-11-10
Protein kinase domain (100%) (view alignment) CDK2 (P24941) - HUMAN 5ANG_A 53.2 1.0E-84 1.9Å WY3 2016-04-13
Protein kinase domain (100%) (view alignment) CDK2 (P24941) CCNA2 (P20248) HUMAN 4EOS_A 53.18 3.0E-85 2.57Å 1RO 2013-02-06
Protein kinase domain (100%) (view alignment) CDK2 (P24941) CCNA2 (P30274) HUMAN 4BCQ_C 53.18 3.0E-85 2.19Å TJF 2013-01-09
Protein kinase domain (100%) (view alignment) CDK2 (P24941) - HUMAN 2W06_A 53.2 1.0E-84 2.04Å FRV 2008-09-23
Protein kinase domain (100%) (view alignment) CDK2 (P24941) - HUMAN 5D1J_A 53.2 1.0E-84 1.79Å 56H 2015-08-12
Protein kinase domain (100%) (view alignment) CDK2 (P24941) - HUMAN 4EK3_A 53.2 1.0E-84 1.34Å - 2013-05-01
Protein kinase domain (100%) (view alignment) CDK2 (P24941) - HUMAN 3SW4_A 53.2 1.0E-84 1.6Å 18K 2012-08-01
Protein kinase domain (100%) (view alignment) CDK1 (P06493) CKS2 (P33552), CCNB1 (P14635) HUMAN 4Y72_A 50.5 6.0E-87 2.3Å LZ9 2015-08-12
Protein kinase domain (100%) (view alignment) CDK1 (P06493) CCNB1 (P14635), (K9J4F7) HUMAN 6GU4_A 50.5 6.0E-87 2.73Å FC8 2018-12-05
Protein kinase domain (100%) (view alignment) CDK2 (P24941) CCNA2 (P20248) HUMAN 2IW8_C 53.16 7.0E-86 2.3Å 4SP 2006-09-06
Protein kinase domain (100%) (view alignment) CDK16 (Q00536) - HUMAN 5G6V_A 77.85 0 2.2Å 919 2016-11-23
Protein kinase domain (100%) (view alignment) CDK2 (P24941) - HUMAN 2W05_A 53.2 1.0E-84 1.9Å FRT 2008-10-14
Protein kinase domain (100%) (view alignment) CDK2 (P24941) - HUMAN 3TI1_A 53.2 1.0E-84 1.99Å B49 2012-08-22
Protein kinase domain (100%) (view alignment) CDK2 (P24941) CCNA2 (P20248) HUMAN 2WHB_A 53.2 1.0E-84 2.9Å - 2009-06-09
Protein kinase domain (100%) (view alignment) CDK2 (P24941) - HUMAN 3UNJ_A 53.2 1.0E-84 1.9Å 0BX 2012-01-25
Protein kinase domain (100%) (view alignment) CDK2 (P24941) CCNA2 (P20248) HUMAN 4EOL_A 53 4.0E-85 2.4Å 1RO 2013-02-06
Protein kinase domain (100%) (view alignment) CDK2 (P24941) E2F1 (Q01094), CCNA2 (P20248) HUMAN 1H24_C 53 2.0E-85 2.5Å - 2003-02-01
Protein kinase domain (100%) (view alignment) CDK2 (P24941) TP53 (P04637), CCNA2 (P20248) HUMAN 1H26_C 53 2.0E-85 2.24Å - 2003-02-01
Protein kinase domain (100%) (view alignment) CDK2 (P24941) CDKN1B (P46527), CCNA2 (P20248) HUMAN 6ATH_A 53.18 3.0E-85 1.82Å - 2018-09-12
Protein kinase domain (100%) (view alignment) CDK2 (P24941) CCNA2 (P20248) HUMAN 1OGU_A 53.16 2.0E-85 2.6Å ST8 2003-09-02
Protein kinase domain (100%) (view alignment) CDK2 (P24941) - HUMAN 4D1X_A 53.2 1.0E-84 2.1Å ESJ 2015-03-18
Protein kinase domain (100%) (view alignment) CDK2 (P24941) CCNA2 (P20248) HUMAN 4EOK_A 53 4.0E-85 2.57Å 4SP 2013-02-06
Protein kinase domain (100%) (view alignment) CDK2 (P24941) CCNA2 (P20248) HUMAN 4BCN_A 53.18 3.0E-85 2.07Å T9N 2013-03-06
Protein kinase domain (100%) (view alignment) CDK2 (P24941) - HUMAN 3TIZ_A 53.2 1.0E-84 2.02Å 3TI 2012-08-22
Protein kinase domain (100%) (view alignment) CDK2 (P24941) - HUMAN 2W17_A 53.2 1.0E-84 2.15Å I19 2008-11-04
Protein kinase domain (100%) (view alignment) CDK2 (P24941) - HUMAN 2XNB_A 53.2 1.0E-84 1.8Å Y8L 2010-11-10
Protein kinase domain (100%) (view alignment) CDK5 (Q00535) CDK5R1 (Q15078) HUMAN 1UNH_B 56.6 2.0E-89 2.25Å IXM 2004-11-10
Protein kinase domain (100%) (view alignment) CDK2 (P24941) CCNA2 (P30274) HUMAN 6GUF_A 53.16 2.0E-85 2.65Å 23D 2018-12-05
Protein kinase domain (100%) (view alignment) CDK2 (P24941) - HUMAN 2VV9_A 53.2 1.0E-84 1.9Å IM9 2008-08-05
Protein kinase domain (100%) (view alignment) CDK1 (P06493) CKS1B (P61024) HUMAN 4YC6_G 50.67 3.0E-86 2.6Å - 2015-05-20
Protein kinase domain (100%) (view alignment) CDK2 (P24941) - HUMAN 3LFQ_A 53.2 1.0E-84 2.03Å A28 2010-03-02
Protein kinase domain (100%) (view alignment) CDK5 (Q00535) CDK5R1 (Q15078) HUMAN 3O0G_A 56.6 2.0E-89 1.95Å - 2011-01-26
Protein kinase domain (100%) (view alignment) CDK2 (P24941) CCNA2 (P20248) HUMAN 4EOO_C 52.84 7.0E-85 2.1Å ATP 2013-02-06
Protein kinase domain (100%) (view alignment) CDK2 (P24941) CCNA2 (P30274) HUMAN 3TNW_C 53.18 3.0E-85 2Å F18 2012-02-15
Protein kinase domain (100%) (view alignment) CDK2 (P24941) CCNA2 (P20248) HUMAN 4EOP_C 52.84 7.0E-85 1.99Å 1RO 2013-02-06
Protein kinase domain (100%) (view alignment) CDK2 (P24941) CCNA2 (P20248) HUMAN 1H1P_C 53 2.0E-85 2.1Å CMG 2002-09-19
Protein kinase domain (100%) (view alignment) CDK2 (P24941) CCNA2 (P20248) HUMAN 4BCP_C 53.18 3.0E-85 2.26Å T3C 2013-04-17
Protein kinase domain (100%) (view alignment) CDK5 (Q00535) CDK5R1 (Q15078) HUMAN 1UNH_A 56.6 2.0E-89 2.25Å IXM 2004-11-10
Protein kinase domain (100%) (view alignment) CDK2 (P24941) - HUMAN 3S2P_A 53.2 1.0E-84 2.3Å PMU 2011-07-20
Protein kinase domain (100%) (view alignment) CDK2 (P24941) CCNA2 (P20248) HUMAN 3F5X_C 53.2 1.0E-84 2.3Å EZV 2009-02-03
Protein kinase domain (100%) (view alignment) CDK2 (P24941) - HUMAN 2VTO_A 53.2 1.0E-84 2.19Å LZ8 2008-08-05
Protein kinase domain (100%) (view alignment) CDK2 (P24941) - HUMAN 2V0D_A 53.2 1.0E-84 2Å C53 2007-06-26
Protein kinase domain (100%) (view alignment) CDK2 (P24941) CCNA2 (P20248) HUMAN 4EOL_C 53 4.0E-85 2.4Å 1RO 2013-02-06
Protein kinase domain (100%) (view alignment) CDK2 (P24941) CCNA2 (P30274) HUMAN 3MY5_A 53.18 3.0E-85 2.1Å RFZ 2010-09-29
Protein kinase domain (100%) (view alignment) CDK2 (P24941) - HUMAN 5ANJ_A 53.2 1.0E-84 1.6Å ZXC 2016-04-13
Protein kinase domain (100%) (view alignment) CDK2 (P24941) CCNA2 (P20248) HUMAN 4CFW_C 53 2.0E-85 2.45Å SQ9 2013-12-18
Protein kinase domain (100%) (view alignment) CDK2 (P24941) CCNA2 (P30274) HUMAN 6GUE_C 53.16 2.0E-85 1.99Å FB8 2018-12-05
Protein kinase domain (100%) (view alignment) CDK2 (P24941) CCNA2 (P30274) HUMAN 3MY5_C 53.18 3.0E-85 2.1Å RFZ 2010-09-29
Protein kinase domain (100%) (view alignment) CDK2 (P24941) - HUMAN 4KD1_A 53.2 1.0E-84 1.7Å 1QK 2013-09-18
Protein kinase domain (100%) (view alignment) CDK2 (P24941) - HUMAN 4D1Z_A 53.2 1.0E-84 1.85Å WG8 2015-03-18
Protein kinase domain (100%) (view alignment) CDK2 (P24941) TP53 (P04637), CCNA2 (P20248) HUMAN 1H26_A 53 2.0E-85 2.24Å - 2003-02-01
Protein kinase domain (100%) (view alignment) CDK2 (P24941) CCNA2 (P20248) HUMAN 4EON_A 52.84 7.0E-85 2.4Å 1RO 2013-02-06
Protein kinase domain (100%) (view alignment) CDK2 (P24941) - HUMAN 4FKO_A 53.2 1.0E-84 1.55Å 20K 2013-05-08
Protein kinase domain (100%) (view alignment) CDK2 (P24941) - HUMAN 3SW7_A 53.2 1.0E-84 1.65Å 19K 2012-08-01
Protein kinase domain (100%) (view alignment) CDK2 (P24941) - HUMAN 5JQ8_A 53.2 1.0E-84 1.94Å I73 2017-02-08
Protein kinase domain (100%) (view alignment) CDK2 (P24941) - HUMAN 5ANO_A 53.2 1.0E-84 1.7Å - 2016-04-13
Protein kinase domain (100%) (view alignment) CDK2 (P24941) - HUMAN 4FKI_A 53.2 1.0E-84 1.6Å 09K 2013-05-08
Protein kinase domain (100%) (view alignment) CDK2 (P24941) RBL1 (P28749), CCNA2 (P20248) HUMAN 1H28_C 53 2.0E-85 2.8Å - 2003-02-01
Protein kinase domain (100%) (view alignment) CDK2 (P24941) - HUMAN 4FKU_A 53.2 1.0E-84 1.47Å 60K 2013-05-08
Protein kinase domain (100%) (view alignment) CDK2 (P24941) Ccna2 (P51943) HUMAN 4II5_A 53.2 1.0E-84 2.15Å ADP 2013-01-23
Protein kinase domain (100%) (view alignment) CDK2 (P24941) CCNA2 (P20248) HUMAN 1H1S_A 53 2.0E-85 2Å 4SP 2002-09-19
Protein kinase domain (100%) (view alignment) CDK1 (P06493) (K9J4F7) HUMAN 6GU7_G 50.5 6.0E-87 2.75Å - 2018-12-05
Protein kinase domain (100%) (view alignment) CDK2 (P24941) CCNA2 (P20248) HUMAN 4CFN_C 53.16 2.0E-85 2.2Å JYM 2013-12-18
Protein kinase domain (100%) (view alignment) CDK2 (P24941) CCNA2 (P20248) HUMAN 5NEV_A 53 2.0E-85 2.97Å 72L 2017-03-29
Protein kinase domain (100%) (view alignment) CDK2 (P24941) - HUMAN 5FP6_A 53.2 1.0E-84 1.85Å MFZ 2015-12-23
Protein kinase domain (100%) (view alignment) CDK1 (P06493) (K9J4F7) HUMAN 6GU7_E 50.5 6.0E-87 2.75Å - 2018-12-05
Protein kinase domain (100%) (view alignment) CDK2 (P24941) CCNA2 (P20248) HUMAN 2V22_A 53.2 1.0E-84 2.6Å - 2008-01-29
Protein kinase domain (100%) (view alignment) CDK2 (P24941) - HUMAN 2VTT_A 53.2 1.0E-84 1.68Å LZD 2008-08-05
Protein kinase domain (100%) (view alignment) CDK2 (P24941) - HUMAN 3UNK_A 53.2 1.0E-84 2.1Å 0BY 2012-01-25
Protein kinase domain (100%) (view alignment) CDK1 (P06493) CKS2 (P33552), CCNB1 (P14635) HUMAN 5LQF_A 50.5 6.0E-87 2.06Å 4SP 2017-01-11
Protein kinase domain (100%) (view alignment) CDK2 (P24941) CCNA2 (P20248) HUMAN 1H1P_A 53 2.0E-85 2.1Å CMG 2002-09-19
Protein kinase domain (100%) (view alignment) CDK2 (P24941) CCNA2 (P30274) HUMAN 3TNW_A 53.18 3.0E-85 2Å F18 2012-02-15
Protein kinase domain (100%) (view alignment) CDK1 (P06493) CCNB1 (P14635), (K9J4F7) HUMAN 6GU3_A 50.5 6.0E-87 2.65Å FB8 2018-12-05
Protein kinase domain (100%) (view alignment) CDK2 (P24941) RBL1 (P28749), CCNA2 (P20248) HUMAN 1H28_A 53 2.0E-85 2.8Å - 2003-02-01
Protein kinase domain (100%) (view alignment) CDK2 (P24941) Ccna2 (P51943) HUMAN 3QHR_A 53.18 5.0E-85 2.17Å ADP 2011-05-25
Protein kinase domain (100%) (view alignment) CDK2 (P24941) - HUMAN 5IEY_A 53.2 1.0E-84 1.66Å 6AE 2016-04-27
Protein kinase domain (100%) (view alignment) CDK2 (P24941) CCNA2 (P20248) HUMAN 4FX3_A 53.2 1.0E-84 2.74Å 60K 2013-05-15
Protein kinase domain (100%) (view alignment) CDK2 (P24941) CCNA2 (P20248) HUMAN 4EOP_A 52.84 7.0E-85 1.99Å 1RO 2013-02-06
Protein kinase domain (100%) (view alignment) CDK2 (P24941) CCNA2 (P30274) HUMAN 6GUF_C 53.16 2.0E-85 2.65Å 23D 2018-12-05
Protein kinase domain (100%) (view alignment) CDK2 (P24941) CCNA2 (P20248) HUMAN 3EID_A 53.2 1.0E-84 3.15Å PO5 2008-10-21
Protein kinase domain (100%) (view alignment) CDK2 (P24941) - HUMAN 2XMY_A 53.2 1.0E-84 1.9Å CDK 2010-11-10
Protein kinase domain (100%) (view alignment) CDK2 (P24941) CCNA2 (P20248) HUMAN 1OI9_A 53.16 2.0E-85 2.1Å N20 2004-07-13
Protein kinase domain (100%) (view alignment) CDK1 (P06493) (K9J4F7) HUMAN 6GU6_A 50.5 6.0E-87 2.33Å 1QK 2018-12-05
Protein kinase domain (100%) (view alignment) CDK2 (P24941) CCNA2 (P20248) HUMAN 4BCP_A 53.18 3.0E-85 2.26Å T3C 2013-04-17
Protein kinase domain (100%) (view alignment) CDK2 (P24941) CCNA2 (P30274) HUMAN 3BHV_C 53.18 3.0E-85 2.1Å VAR 2008-02-12
Protein kinase domain (100%) (view alignment) CDK2 (P24941) CCNA2 (P30274) HUMAN 6GUE_A 53.16 2.0E-85 1.99Å FB8 2018-12-05
Protein kinase domain (100%) (view alignment) CDK2 (P24941) - HUMAN 4FKW_A 53.2 1.0E-84 1.8Å 62K 2013-05-08
Protein kinase domain (100%) (view alignment) CDK2 (P24941) CCNA2 (P20248) HUMAN 2V22_C 53.2 1.0E-84 2.6Å - 2008-01-29
Protein kinase domain (100%) (view alignment) CDK5 (Q00535) CDK5R1 (Q15078) HUMAN 1UNG_A 56.6 2.0E-89 2.3Å ALH 2004-11-10
Protein kinase domain (100%) (view alignment) CDK2 (P24941) Ccna2 (P51943) HUMAN 3QHR_C 53.18 5.0E-85 2.17Å ADP 2011-05-25
Protein kinase domain (100%) (view alignment) CDK2 (P24941) CCNA2 (P20248) HUMAN 4EOQ_A 53 3.0E-85 2.15Å ATP 2013-02-06
Protein kinase domain (100%) (view alignment) CDK2 (P24941) - HUMAN 4NJ3_A 53.2 1.0E-84 1.848Å 2KD 2013-11-27
Protein kinase domain (100%) (view alignment) CDK2 (P24941) CCNA2 (P20248) HUMAN 4EON_C 52.84 7.0E-85 2.4Å 1RO 2013-02-06
Protein kinase domain (100%) (view alignment) CDK2 (P24941) - HUMAN 4EK8_A 53.2 1.0E-84 1.7Å 16K 2013-05-01
Protein kinase domain (100%) (view alignment) CDK2 (P24941) CCNA2 (P30274) HUMAN 6GUB_A 53.16 2.0E-85 2.52Å F9Z 2018-12-05
Protein kinase domain (100%) (view alignment) CDK2 (P24941) CCNA2 (P20248) HUMAN 2IW6_A 53.16 3.0E-85 2.3Å QQ2 2006-09-06
Protein kinase domain (100%) (view alignment) CDK2 (P24941) CCNA2 (P30274) HUMAN 3BHU_A 53.18 3.0E-85 2.3Å MHR 2008-02-12
Protein kinase domain (100%) (view alignment) CDK2 (P24941) - HUMAN 4FKL_A 53.2 1.0E-84 1.26Å CK2 2013-05-08
Protein kinase domain (100%) (view alignment) CDK2 (P24941) - HUMAN 2VU3_A 53.2 1.0E-84 1.85Å LZE 2008-08-05
Protein kinase domain (100%) (view alignment) CDK1 (P06493) CKS2 (P33552), CCNB1 (P14635) HUMAN 5LQF_D 50.5 6.0E-87 2.06Å 4SP 2017-01-11
Protein kinase domain (100%) (view alignment) CDK2 (P24941) CCNA2 (P20248) HUMAN 5CYI_C 53 2.0E-85 2Å 55S 2015-09-16
Protein kinase domain (100%) (view alignment) CDK2 (P24941) CCNA2 (P20248) HUMAN 5NEV_C 53 2.0E-85 2.97Å 72L 2017-03-29
Protein kinase domain (100%) (view alignment) CDK2 (P24941) Ccna2 (P51943) HUMAN 3QHW_A 53.18 5.0E-85 1.908Å ADP 2011-05-25
Protein kinase domain (100%) (view alignment) CDK2 (P24941) CCNA2 (P20248) HUMAN 4CFV_C 53.18 3.0E-85 2Å 75X 2014-12-10
Protein kinase domain (100%) (view alignment) CDK2 (P24941) CCNA2 (P20248) HUMAN 1H1R_C 53 2.0E-85 2Å 6CP 2002-09-19
Protein kinase domain (100%) (view alignment) CDK2 (P24941) RB1 (P06400), CCNA2 (P20248) HUMAN 1H25_C 53 2.0E-85 2.5Å - 2003-02-01
Protein kinase domain (100%) (view alignment) CDK2 (P24941) CCNA2 (P20248) HUMAN 4FX3_C 53.2 1.0E-84 2.74Å 60K 2013-05-15
Protein kinase domain (100%) (view alignment) CDK2 (P24941) - HUMAN 2VTA_A 53.2 1.0E-84 2Å LZ1 2008-08-05
Protein kinase domain (100%) (view alignment) CDK2 (P24941) - HUMAN 2VTP_A 53.2 1.0E-84 2.15Å LZ9 2008-08-05
Protein kinase domain (100%) (view alignment) CDK2 (P24941) - HUMAN 4FKR_A 53.2 1.0E-84 1.85Å 45K 2013-05-08
Protein kinase domain (100%) (view alignment) CDK2 (P24941) CCNA2 (P20248) HUMAN 4CFX_A 53 2.0E-85 2.95Å G6T 2014-12-10
Protein kinase domain (100%) (view alignment) CDK2 (P24941) - HUMAN 3EZR_A 53.18 3.0E-85 1.9Å EZR 2009-02-03
Protein kinase domain (100%) (view alignment) CDK5 (Q00535) - HUMAN 4AU8_A 57.14 7.0E-90 1.9Å Z3R 2013-03-27
Protein kinase domain (100%) (view alignment) CDK2 (P24941) CCNA2 (P20248) HUMAN 4CFM_A 53 2.0E-85 2.85Å 4QE 2014-12-10
Protein kinase domain (100%) (view alignment) CDK1 (P06493) CKS1B (P61024) HUMAN 4YC6_E 50.67 3.0E-86 2.6Å - 2015-05-20
Protein kinase domain (100%) (view alignment) CDK2 (P24941) - HUMAN 4EK4_A 53.2 1.0E-84 1.26Å 1CK 2013-05-01
Protein kinase domain (100%) (view alignment) CDK2 (P24941) CCNA2 (P20248) HUMAN 2IW6_C 53.16 3.0E-85 2.3Å QQ2 2006-09-06
Protein kinase domain (100%) (view alignment) CDK2 (P24941) CCNA2 (P20248) HUMAN 4CFX_C 53 2.0E-85 2.95Å G6T 2014-12-10
Protein kinase domain (100%) (view alignment) CDK2 (P24941) - HUMAN 4BZD_A 53.2 1.0E-84 1.83Å D6I 2014-08-13
Protein kinase domain (100%) (view alignment) CDK2 (P24941) - HUMAN 3EZV_A 53.18 3.0E-85 1.99Å EZV 2009-02-03
Protein kinase domain (100%) (view alignment) CDK1 (P06493) (K9J4F7) HUMAN 6GU7_A 50.5 6.0E-87 2.75Å FB8 2018-12-05
Protein kinase domain (100%) (view alignment) CDK2 (P24941) CCNA2 (P20248) HUMAN 4BCK_A 53.18 3.0E-85 2.05Å T3E 2013-03-06
Protein kinase domain (100%) (view alignment) CDK2 (P24941) - HUMAN 3IGG_A 53.2 1.0E-84 1.8Å EFQ 2009-09-08
Protein kinase domain (100%) (view alignment) CDK2 (P24941) - HUMAN 4FKQ_A 53.2 1.0E-84 1.75Å 42K 2013-05-08
Protein kinase domain (100%) (view alignment) CDK2 (P24941) - HUMAN 5IEV_A 53.2 1.0E-84 2.03Å R0N 2016-04-27
Protein kinase domain (100%) (view alignment) CDK2 (P24941) - HUMAN 4FKJ_A 53.2 1.0E-84 1.63Å 11K 2013-05-08
Protein kinase domain (100%) (view alignment) CDK1 (P06493) CKS2 (P33552), CCNB1 (P14635) HUMAN 5HQ0_A 50.5 6.0E-87 2.3Å LZ9 2016-03-02
Protein kinase domain (100%) (view alignment) CDK2 (P24941) CCNA2 (P30274) HUMAN 3BHV_A 53.18 3.0E-85 2.1Å VAR 2008-02-12
Protein kinase domain (100%) (view alignment) CDK2 (P24941) CCNA2 (P20248) HUMAN 4BCM_C 53.18 3.0E-85 2.39Å T7Z 2013-03-06
Protein kinase domain (100%) (view alignment) CDK2 (P24941) CCNA2 (P20248) HUMAN 4BCK_C 53.18 3.0E-85 2.05Å T3E 2013-03-06
Protein kinase domain (100%) (view alignment) CDK2 (P24941) CCNA2 (P20248) HUMAN 3EJ1_A 53.2 1.0E-84 3.22Å 5BP 2008-10-21
Protein kinase domain (100%) (view alignment) CDK2 (P24941) - HUMAN 3WBL_A 53.2 1.0E-84 2Å PDY 2013-10-30
Protein kinase domain (100%) (view alignment) CDK2 (P24941) - HUMAN 3TIY_A 53.2 1.0E-84 1.84Å TIY 2012-08-22
Protein kinase domain (100%) (view alignment) CDK2 (P24941) CCNA2 (P20248) HUMAN 2WFY_A 53.2 1.0E-84 2.53Å - 2009-06-09
Protein kinase domain (100%) (view alignment) CDK2 (P24941) - HUMAN 5AND_A 53.2 1.0E-84 2.3Å 5JE 2016-04-13
Protein kinase domain (100%) (view alignment) CDK2 (P24941) - HUMAN 5A14_A 53.2 1.0E-84 2Å LQ5 2015-07-22
Protein kinase domain (100%) (view alignment) CDK2 (P24941) CCNA2 (P20248) HUMAN 4EOO_A 52.84 7.0E-85 2.1Å ATP 2013-02-06
Protein kinase domain (100%) (view alignment) CDK2 (P24941) - HUMAN 5ANE_A 53.2 1.0E-84 1.7Å SZL 2016-04-13
Protein kinase domain (100%) (view alignment) CDK16 (Q00536) - HUMAN 5G6V_B 77.85 0 2.2Å 919 2016-11-23
Protein kinase domain (100%) (view alignment) CDK2 (P24941) - HUMAN 2VTJ_A 53.2 1.0E-84 2.2Å LZ4 2008-08-05
Protein kinase domain (100%) (view alignment) CDK2 (P24941) CCNA2 (P20248) HUMAN 3EID_C 53.2 1.0E-84 3.15Å - 2008-10-21
Protein kinase domain (100%) (view alignment) CDK2 (P24941) CCNA2 (P20248) HUMAN 1OIU_A 53.16 2.0E-85 2Å N76 2004-07-13
Protein kinase domain (100%) (view alignment) CDK2 (P24941) CCNA2 (P20248) HUMAN 1OIY_A 53.16 2.0E-85 2.4Å N41 2004-07-13
Protein kinase domain (100%) (view alignment) CDK1 (P06493) CCNB1 (P14635), (K9J4F7) HUMAN 6GU2_A 50.5 6.0E-87 2Å F9Z 2018-12-05
Protein kinase domain (100%) (view alignment) CDK2 (P24941) - HUMAN 2VTH_A 53.2 1.0E-84 1.9Å LZ2 2008-08-05
Protein kinase domain (100%) (view alignment) CDK16 (Q00536) - HUMAN 3MTL_A 77.85 0 2.4Å FEF 2010-06-09
Protein kinase domain (100%) (view alignment) CDK2 (P24941) - HUMAN 2VTR_A 53.2 1.0E-84 1.89Å LZB 2008-08-05
Protein kinase domain (100%) (view alignment) CDK2 (P24941) CCNA2 (P20248) HUMAN 4BCN_C 53.18 3.0E-85 2.07Å T9N 2013-03-06
Protein kinase domain (100%) (view alignment) CDK2 (P24941) CCNA2 (P20248) HUMAN 4BCM_A 53.18 3.0E-85 2.39Å T7Z 2013-03-06
Protein kinase domain (100%) (view alignment) CDK2 (P24941) - HUMAN 3IG7_A 53.2 1.0E-84 1.8Å EFP 2009-09-08
Protein kinase domain (100%) (view alignment) CDK2 (P24941) - HUMAN 2W1H_A 53.2 1.0E-84 2.15Å L0F 2009-01-27
Protein kinase domain (100%) (view alignment) CDK2 (P24941) - HUMAN 5IEX_A 53.2 1.0E-84 2.03Å 6AF 2016-04-27
Protein kinase domain (100%) (view alignment) CDK2 (P24941) - HUMAN 2VTN_A 53.2 1.0E-84 2.2Å LZ7 2008-08-05
Protein kinase domain (100%) (view alignment) CDK5 (Q00535) CDK5R1 (Q15078) HUMAN 1H4L_B 56.6 1.0E-89 2.65Å - 2002-08-14
Protein kinase domain (100%) (view alignment) CDK2 (P24941) - HUMAN 2VTI_A 53.2 1.0E-84 2Å LZ3 2008-08-05
Protein kinase domain (100%) (view alignment) CDK2 (P24941) - HUMAN 4EK5_A 53.2 1.0E-84 1.52Å 03K 2013-05-01
Protein kinase domain (100%) (view alignment) CDK2 (P24941) CCNA2 (P20248) HUMAN 5CYI_A 53 2.0E-85 2Å 55S 2015-09-16
Protein kinase domain (100%) (view alignment) CDK5 (Q00535) CDK5R1 (Q15078) HUMAN 1H4L_A 56.6 1.0E-89 2.65Å - 2002-08-14
Protein kinase domain (100%) (view alignment) CDK2 (P24941) - HUMAN 2UZN_A 53.2 1.0E-84 2.1Å C96 2007-06-26
Protein kinase domain (100%) (view alignment) CDK2 (P24941) CCNA2 (P20248) HUMAN 2IW9_A 53.16 3.0E-85 2Å 4SP 2006-09-06
Protein kinase domain (100%) (view alignment) CDK2 (P24941) CCNA2 (P20248) HUMAN 2X1N_C 53.2 1.0E-84 2.75Å X1N 2010-02-16
Protein kinase domain (100%) (view alignment) CDK2 (P24941) CCNA2 (P20248) HUMAN 1H1Q_C 53 2.0E-85 2.5Å 2A6 2002-09-19
Protein kinase domain (100%) (view alignment) CDK2 (P24941) E2F1 (Q01094), CCNA2 (P20248) HUMAN 1H24_A 53 2.0E-85 2.5Å - 2003-02-01
Protein kinase domain (100%) (view alignment) CDK2 (P24941) CCNA2 (P20248) HUMAN 2WEV_C 53.2 1.0E-84 2.3Å CK7 2009-06-09
Protein kinase domain (100%) (view alignment) CDK2 (P24941) - HUMAN 4LYN_A 53.2 1.0E-84 2Å 1YG 2013-10-02
Protein kinase domain (100%) (view alignment) CDK2 (P24941) - HUMAN 2VTM_A 53.2 1.0E-84 2.25Å LZM 2008-08-05
Protein kinase domain (100%) (view alignment) CDK5 (Q00535) - HUMAN 4AU8_B 57.14 7.0E-90 1.9Å Z3R 2013-03-27
Protein kinase domain (100%) (view alignment) CDK5 (Q00535) CDK5R1 (Q15078) HUMAN 1UNL_B 56.6 2.0E-89 2.2Å - 2004-11-10
Protein kinase domain (100%) (view alignment) CDK2 (P24941) - HUMAN 4FKP_A 53.2 1.0E-84 1.6Å LS5 2013-05-08
Protein kinase domain (100%) (view alignment) CDK2 (P24941) CCNA2 (P20248) HUMAN 4EOK_C 53 4.0E-85 2.57Å 4SP 2013-02-06
Protein kinase domain (100%) (view alignment) CDK2 (P24941) CCNA2 (P20248) HUMAN 4CFV_A 53.18 3.0E-85 2Å 75X 2014-12-10
Protein kinase domain (100%) (view alignment) CDK2 (P24941) CCNA2 (P30274) HUMAN 6GUB_C 53.16 2.0E-85 2.52Å F9Z 2018-12-05
Protein kinase domain (100%) (view alignment) CDK1 (P06493) CKS1B (P61024) HUMAN 4YC6_C 50.67 3.0E-86 2.6Å - 2015-05-20
Protein kinase domain (100%) (view alignment) CDK2 (P24941) CDKN1B (P46527), CCNA2 (P20248) HUMAN 1H27_C 53 2.0E-85 2.2Å - 2003-02-01
Protein kinase domain (100%) (view alignment) CDK5 (Q00535) CDK5R1 (Q15078) HUMAN 1UNG_B 56.6 2.0E-89 2.3Å ALH 2004-11-10
Protein kinase domain (100%) (view alignment) CDK2 (P24941) CCNA2 (P30274) HUMAN 4BCO_C 53.18 3.0E-85 1.58Å T6Q 2013-01-09
Protein kinase domain (100%) (view alignment) CDK2 (P24941) CCNA2 (P20248) HUMAN 1H1R_A 53 2.0E-85 2Å 6CP 2002-09-19
Protein kinase domain (100%) (view alignment) CDK2 (P24941) - HUMAN 4BGH_A 53.2 1.0E-84 1.949Å 3I6 2013-09-04
Protein kinase domain (100%) (view alignment) CDK2 (P24941) - HUMAN 3ULI_A 53.2 1.0E-84 2Å 1N3 2013-08-14
Protein kinase domain (100%) (view alignment) CDK2 (P24941) CCNA2 (P20248) HUMAN 1OI9_C 53.16 2.0E-85 2.1Å N20 2004-07-13
Protein kinase domain (100%) (view alignment) CDK2 (P24941) CCNA2 (P30274) HUMAN 6GUC_C 53.16 2.0E-85 2Å SU9 2018-12-05
Protein kinase domain (100%) (view alignment) CDK2 (P24941) - HUMAN 3LFS_A 53.2 1.0E-84 2.4Å A07 2010-03-02
Protein kinase domain (100%) (view alignment) CDK2 (P24941) CCNA2 (P20248) HUMAN 3EJ1_C 53.2 1.0E-84 3.22Å 5BP 2008-10-21
Protein kinase domain (100%) (view alignment) CDK2 (P24941) - HUMAN 5ANI_A 53.2 1.0E-84 1.9Å ES4 2016-04-13
Protein kinase domain (100%) (view alignment) CDK2 (P24941) CCNA2 (P20248) HUMAN 2WHB_C 53.2 1.0E-84 2.9Å - 2009-06-09
Protein kinase domain (100%) (view alignment) CDK2 (P24941) - HUMAN 2VTL_A 53.2 1.0E-84 2Å LZ5 2008-08-05
Protein kinase domain (100%) (view alignment) CDK2 (P24941) RB1 (P06400), CCNA2 (P20248) HUMAN 1H25_A 53 2.0E-85 2.5Å - 2003-02-01
Protein kinase domain (100%) (view alignment) CDK2 (P24941) CCNA2 (P20248) HUMAN 5IF1_A 53.2 1.0E-84 2.61Å - 2016-04-27
Protein kinase domain (100%) (view alignment) CDK2 (P24941) - HUMAN 5ANK_A 53.2 1.0E-84 1.9Å RJI 2016-04-13
Protein kinase domain (100%) (view alignment) CDK2 (P24941) CCNA2 (P20248) 3EOC_C 53.2 1.0E-84 3.2Å T2A 2008-11-04
Protein kinase domain (100%) (view alignment) CDK2 (P24941) CCNA2 (P20248) HUMAN 3F5X_A 53.2 1.0E-84 2.3Å EZV 2009-02-03
Protein kinase domain (100%) (view alignment) CDK5 (Q00535) CDK5R1 (Q15078) HUMAN 3O0G_B 56.6 2.0E-89 1.95Å 3O0 2011-01-26
Protein kinase domain (100%) (view alignment) CDK2 (P24941) CCNA2 (P20248) HUMAN 1OGU_C 53.16 2.0E-85 2.6Å ST8 2003-09-02
Protein kinase domain (100%) (view alignment) CDK2 (P24941) CCNA2 (P20248) HUMAN 4EOS_C 53.18 3.0E-85 2.57Å 1RO 2013-02-06
Protein kinase domain (100%) (view alignment) CDK2 (P24941) - HUMAN 3FZ1_A 53.2 1.0E-84 1.9Å B98 2009-04-07
Protein kinase domain (100%) (view alignment) CDK2 (P24941) CCNA2 (P20248) 2WMB_A 53 2.0E-85 2.5Å - 2010-09-01
Protein kinase domain (100%) (view alignment) CDK1 (P06493) (K9J4F7) HUMAN 6GU7_C 50.5 6.0E-87 2.75Å - 2018-12-05
Protein kinase domain (100%) (view alignment) CDK2 (P24941) CCNA2 (P20248) 2WMA_A 53 2.0E-85 2.8Å - 2010-09-01
Protein kinase domain (100%) (view alignment) CDK2 (P24941) - HUMAN 5JQ5_A 53.2 1.0E-84 1.94Å I74 2017-02-08
Protein kinase domain (100%) (view alignment) CDK2 (P24941) - HUMAN 4FKV_A 53.2 1.0E-84 1.7Å 61K 2013-05-08
Protein kinase domain (100%) (view alignment) CDK2 (P24941) - HUMAN 4FKS_A 53.2 1.0E-84 1.54Å 46K 2013-05-08
Protein kinase domain (100%) (view alignment) CDK2 (P24941) CCNA2 (P30274) HUMAN 4BCO_A 53.18 3.0E-85 1.58Å T6Q 2013-01-09
Protein kinase domain (100%) (view alignment) CDK2 (P24941) - HUMAN 3LE6_A 53.2 1.0E-84 2Å 2BZ 2010-11-17
Protein kinase domain (100%) (view alignment) CDK2 (P24941) CCNA2 (P20248) HUMAN 1H1Q_A 53 2.0E-85 2.5Å 2A6 2002-09-19
Protein kinase domain (100%) (view alignment) CDK2 (P24941) - HUMAN 3NS9_A 53.2 1.0E-84 1.78Å NS9 2010-12-08
Protein kinase domain (100%) (view alignment) CDK2 (P24941) - HUMAN 4EK6_A 53.2 1.0E-84 1.52Å 10K 2013-05-01
Protein kinase domain (100%) (view alignment) CDK2 (P24941) - HUMAN 4ACM_A 53.2 1.0E-84 1.63Å 7YG 2012-05-16
Protein kinase domain (100%) (view alignment) CDK2 (P24941) CCNA2 (P20248) HUMAN 4EOJ_C 53 4.0E-85 1.65Å ATP 2013-02-06
Protein kinase domain (100%) (view alignment) CDK2 (P24941) CCNA2 (P20248) HUMAN 4EOQ_C 53 3.0E-85 2.15Å ATP 2013-02-06
Protein kinase domain (100%) (view alignment) CDK2 (P24941) - HUMAN 2UZO_A 53.2 1.0E-84 2.2Å C62 2007-06-26
Protein kinase domain (100%) (view alignment) CDK2 (P24941) CCNA2 (P20248) HUMAN 4CFU_A 53.18 3.0E-85 2.2Å 2WC 2014-12-10
Protein kinase domain (100%) (view alignment) CDK2 (P24941) CCNA2 (P20248) HUMAN 4CFU_C 53.18 3.0E-85 2.2Å 2WC 2014-12-10
Protein kinase domain (100%) (view alignment) CDK2 (P24941) - HUMAN 5OO0_A 53 2.0E-85 1.6Å 9YZ 2018-03-14
Protein kinase domain (100%) (view alignment) CDK2 (P24941) CCNA2 (P20248) HUMAN 4CFM_C 53 2.0E-85 2.85Å 4QE 2014-12-10
Protein kinase domain (100%) (view alignment) CDK2 (P24941) CCNA2 (P20248) 3EOC_A 53.2 1.0E-84 3.2Å T2A 2008-11-04
Protein kinase domain (100%) (view alignment) CDK2 (P24941) - HUMAN 4FKG_A 53.2 1.0E-84 1.51Å 4CK 2013-05-08
Protein kinase domain (100%) (view alignment) CDK2 (P24941) - HUMAN 3LFN_A 53.2 1.0E-84 2.28Å A27 2010-03-02