Molecular Target Synopsis
Overview
Domains and Structures
Drugs and Clinical Candidates
Druggability
Chemistry
Ligand Efficiency Plot
Pathways
Family Cladogram
Interaction Network
Gene Expression
Gene Copy Number Variation
RNAi
Mutations
Germline Genetics

trpC (Q06121) - Overview - Molecular Target Synopsis

Protein


trpC, Indole-3-glycerol phosphate synthase
Enzyme Classification 4.1.1.48
UniProt Q06121

Also Known as TRPC_SACS2, trpC

Monomer.

5AOU
STRUCTURE OF THE ENGINEERED RETRO-ALDOLASE RA95.5-8F APO
RCSB/PDB
Inspect Structure
See all 3D Structures for trpC

Isoforms / Transcripts (Protein Coding)


Protein Length Ensembl Gene Ensembl Transcript Ensembl Protein Uniprot Isoform
248Q06121-1

Gene Copy Number Variation


In COSMIC - Cell Lines Project trpC has gain in 0 cell-lines, loss in 0 cell-lines and no signal in 0 cell-lines. (see details)

3D Structures


For trpC there are:
21 structures (24 chains) solved
12 are solved in complex with at least one small molecule ligand
1 are solved with an approved drug

trpC is solved in complex with the approved drug(s):

BEZ/BENZOIC ACID (4OU1_A).

(see details)
Molecular Target 3D Synopsis