Molecular Target Synopsis
Overview
Domains and Structures
Drugs and Clinical Candidates
Druggability
Chemistry
Ligand Efficiency Plot
Pathways
Family Cladogram
Interaction Network
Gene Expression
Gene Copy Number Variation
RNAi
Mutations
Germline Genetics

ypkA (Q05608) - Overview - Molecular Target Synopsis

Protein


ypkA, Protein kinase YpkA
Enzyme Classification 2.7.11.1
UniProt Q05608

Also Known as YPKA_YERPS, ypkA

Acts as a virulence determinant.

2H7O
CRYSTAL STRUCTURE OF THE RHO-GTPASE BINDING DOMAIN OF YPKA
RCSB/PDB
Inspect Structure
See all 3D Structures for ypkA

Isoforms / Transcripts (Protein Coding)


Protein Length Ensembl Gene Ensembl Transcript Ensembl Protein Uniprot Isoform
732Q05608-1

Sub-cellular localization


UniProt: ypkA is active in the following subcellular-locations: secreted.
GO terms: ypkA is active in the following subcellular-locations: extracellular region.



UniProt
GO terms

Gene Copy Number Variation


In COSMIC - Cell Lines Project ypkA has gain in 0 cell-lines, loss in 0 cell-lines and no signal in 0 cell-lines. (see details)

3D Structures


For ypkA there are:
2 structures (3 chains) solved
0 are solved in complex with at least one small molecule ligand



(see details)
Molecular Target 3D Synopsis

Screening and Chemistry


ypkA has been screened with compounds ( bioactivities). (see details)