Molecular Target Synopsis
Overview
Domains and Structures
Drugs and Clinical Candidates
Druggability
Chemistry
Ligand Efficiency Plot
Pathways
Family Cladogram
Interaction Network
Gene Expression
Gene Copy Number Variation
RNAi
Mutations
Germline Genetics

CIA1 (Q05583) - Overview - Molecular Target Synopsis

Protein


CIA1, Cytosolic iron-sulfur protein assembly protein 1
UniProt Q05583

Also Known as CIAO1_YEAST, CIA1

Essential component of the cytosolic iron-sulfur (Fe/S) protein assembly machinery. Required for the maturation of extramitochondrial Fe/S proteins. Interacts with NAR1.

2HES
CYTOSOLIC IRON-SULPHUR ASSEMBLY PROTEIN- 1
RCSB/PDB
Inspect Structure
See all 3D Structures for CIA1

Isoforms / Transcripts (Protein Coding)


Protein Length Ensembl Gene Ensembl Transcript Ensembl Protein Uniprot Isoform
330Q05583-1

Sub-cellular localization


UniProt: CIA1 is active in the following subcellular-locations: cytoplasm, nucleus.
GO terms: CIA1 is active in the following subcellular-locations: CIA complex, cytoplasm, cytosol, nucleus.



UniProt
GO terms

Gene Copy Number Variation


In COSMIC - Cell Lines Project CIA1 has gain in 0 cell-lines, loss in 0 cell-lines and no signal in 0 cell-lines. (see details)

3D Structures


For CIA1 there are:
1 structures (1 chains) solved
0 are solved in complex with at least one small molecule ligand



(see details)
Molecular Target 3D Synopsis