Molecular Target Synopsis
Overview
Domains and Structures
Drugs and Clinical Candidates
Druggability
Chemistry
Ligand Efficiency Plot
Pathways
Family Cladogram
Interaction Network
Gene Expression
Gene Copy Number Variation
RNAi
Mutations
Germline Genetics

pksL (Q05470) - Overview - Molecular Target Synopsis

Protein


pksL, Polyketide synthase PksL
UniProt Q05470

Also Known as PKSL_BACSU, pksL, outG, pksA, pksX

Involved in some intermediate steps for the synthesis of the antibiotic polyketide bacillaene which is involved in secondary metabolism.

5E1V
CRYSTAL STRUCTURE OF A MONOMERIC DEHYDRATASE DOMAIN FROM A TRANS AT POLYKETIDE SYNTHASE SPLIT MODULE
RCSB/PDB
Inspect Structure
See all 3D Structures for pksL

Isoforms / Transcripts (Protein Coding)


Protein Length Ensembl Gene Ensembl Transcript Ensembl Protein Uniprot Isoform
4538Q05470-1

Sub-cellular localization


UniProt: pksL is active in the following subcellular-locations: cytoplasm.
GO terms: pksL is active in the following subcellular-locations: cytoplasm.



UniProt
GO terms

Gene Copy Number Variation


In COSMIC - Cell Lines Project pksL has gain in 0 cell-lines, loss in 0 cell-lines and no signal in 0 cell-lines. (see details)

3D Structures


For pksL there are:
5 structures (18 chains) solved
0 are solved in complex with at least one small molecule ligand



(see details)
Molecular Target 3D Synopsis

Screening and Chemistry


pksL has been screened with compounds ( bioactivities). (see details)