Molecular Target Synopsis
Overview
Domains and Structures
Drugs and Clinical Candidates
Druggability
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MST1R (Q04912) - Domains And Structures - Molecular Target Synopsis

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Structural Sequence Similarity Matches
Domains Covered Gene Name (Uniprot) Solved in Complex with Organism PDB Chain Identity E-Value Resolution Ligands Release Date
Protein tyrosine kinase (100%) (view alignment) MET (P08581) - HUMAN 3F66_A 61.62 3.0E-109 1.4Å IHX 2008-12-23
Protein tyrosine kinase (100%) (view alignment) FGFR2 (P21802) - HUMAN 2PSQ_A 35.91 7.0E-52 2.4Å - 2007-09-25
Protein tyrosine kinase (100%) (view alignment) MERTK (Q12866) - HUMAN 5TD2_A 40.69 1.0E-61 2.68Å 7AE 2017-01-25
Protein tyrosine kinase (100%) (view alignment) MET (P08581) - HUMAN 4KNB_D 62.46 2.0E-106 2.4Å 1RU 2014-04-30
Protein tyrosine kinase (100%) (view alignment) MERTK (Q12866) - HUMAN 4MHA_A 40.48 3.0E-61 2.59Å 4MH 2014-05-21
Protein tyrosine kinase (100%) (view alignment) MET (P08581) - HUMAN 5T3Q_A 61.74 1.0E-109 2Å 75H 2016-09-21
Sema domain (100%) (view alignment) MST1R (Q04912) - HUMAN 4FWW_A 100 0 1.85Å NAG BMA 2012-08-08
Protein tyrosine kinase (98%) (view alignment) Abl1 (P00520) - MOUSE 3DK7_A 38.85 6.0E-53 2.01Å SX7 2008-07-29
Protein tyrosine kinase (100%) (view alignment) MERTK (Q12866) - HUMAN 3BPR_C 40.48 3.0E-61 2.8Å OLP 2008-01-29
Protein tyrosine kinase (100%) (view alignment) IGF1R (P08069) - HUMAN 5HZN_A 37.59 1.0E-53 2.2Å 66A MES 2016-04-06
Protein tyrosine kinase (100%) (view alignment) MERTK (Q12866) - HUMAN 5U6C_B 40.48 1.0E-61 2.1Å 7YS 2017-07-26
Protein tyrosine kinase (100%) (view alignment) AXL (P30530) - HUMAN 5U6B_D 40.8 9.0E-61 2.84Å 7YS 2017-07-26
Protein tyrosine kinase (100%) (view alignment) PTK2B (Q14289) - HUMAN 5TO8_A 37.64 2.0E-52 1.98Å 7FM 2016-12-21
Protein tyrosine kinase (100%) (view alignment) IGF1R (P08069) - HUMAN 3F5P_L 37.93 6.0E-54 2.9Å 741 2008-12-30
Protein tyrosine kinase (100%) (view alignment) FGFR2 (P21802) - HUMAN 1OEC_A 36.33 4.0E-52 2.4Å AA2 2004-10-27
Protein tyrosine kinase (100%) (view alignment) IGF1R (P08069) - HUMAN 5FXR_A 37.93 5.0E-54 2.4Å 8LN 2016-10-19
Protein tyrosine kinase (100%) (view alignment) MET (P08581) - HUMAN 3I5N_A 61.74 1.0E-109 2Å B2D 2010-01-12
Protein tyrosine kinase (100%) (view alignment) MET (P08581) - HUMAN 3ZXZ_A 61.36 1.0E-107 1.8Å KRW 2011-08-31
Protein tyrosine kinase (100%) (view alignment) AXL (P30530) - HUMAN 5U6B_B 40.8 9.0E-61 2.84Å 7YS 2017-07-26
Protein tyrosine kinase (100%) (view alignment) MET (P08581) - HUMAN 4DEH_A 61.74 1.0E-109 2Å 0JK 2012-05-30
Protein tyrosine kinase (100%) (view alignment) MET (P08581) - HUMAN 3U6H_A 61.74 1.0E-109 2Å 03X 2012-02-22
Protein tyrosine kinase (100%) (view alignment) INSR (P06213) Irs2 (P81122) HUMAN 3BU6_A 37.81 8.0E-52 1.95Å - 2008-02-19
Protein tyrosine kinase (100%) (view alignment) MET (P08581) - HUMAN 1R1W_A 60.26 9.0E-111 1.8Å - 2003-10-07
Protein tyrosine kinase (100%) (view alignment) IGF1R (P08069) - HUMAN 3F5P_M 37.93 6.0E-54 2.9Å 741 2008-12-30
Protein tyrosine kinase (100%) (view alignment) IGF1R (P08069) - HUMAN 3F5P_G 37.93 6.0E-54 2.9Å 741 2008-12-30
Protein tyrosine kinase (100%) (view alignment) Tyro3 (P55144) - MOUSE 4FEQ_A 41.61 3.0E-61 2.2Å 0T8 2013-03-13
Protein tyrosine kinase (100%) (view alignment) IGF1R (P08069) - HUMAN 3F5P_B 37.93 6.0E-54 2.9Å 741 2008-12-30
Protein tyrosine kinase (98%) (view alignment) - 4CSV_A 41.06 1.0E-54 2.05Å STI 2015-03-04
Protein tyrosine kinase (99%) (view alignment) IGF1R (P08069) - HUMAN 3QQU_A 38.6 5.0E-53 2.9Å 01P 2011-04-20
Protein tyrosine kinase (98%) (view alignment) FGFR2 (P21802) - HUMAN 2PZ5_B 38.35 7.0E-52 2.4Å ACP 2007-09-25
Protein tyrosine kinase (100%) (view alignment) MET (P08581) - HUMAN 3F82_A 60.26 8.0E-111 2.5Å 353 2009-03-31
Protein tyrosine kinase (100%) (view alignment) IGF1R (P08069) - HUMAN 3F5P_E 37.93 6.0E-54 2.9Å 741 2008-12-30
Protein tyrosine kinase (100%) (view alignment) Abl2 (Q4JIM5) - MOUSE 4XLI_B 38.99 3.0E-52 2.5Å 1N1 2015-04-01
Protein tyrosine kinase (100%) (view alignment) IGF1R (P08069) - HUMAN 1M7N_B 37.93 2.0E-53 2.7Å - 2003-01-07
Protein tyrosine kinase (100%) (view alignment) IGF1R (P08069) - HUMAN 1JQH_C 37.93 6.0E-54 2.1Å ANP 2002-04-19
Protein tyrosine kinase (99%) (view alignment) IGF1R (P08069) IRS1 (P35568) HUMAN 1K3A_A 38.6 1.0E-52 2.1Å ACP 2001-11-28
Protein tyrosine kinase (100%) (view alignment) IGF1R (P08069) - HUMAN 3LW0_B 37.59 1.0E-53 1.79Å CCX 2010-09-29
Protein tyrosine kinase (100%) (view alignment) MERTK (Q12866) - HUMAN 3TCP_B 40.48 3.0E-61 2.69Å CKJ 2012-06-20
Protein tyrosine kinase (100%) (view alignment) MET (P08581) - HUMAN 5HO6_A 60.26 9.0E-111 1.97Å 63K 2016-11-23
Protein tyrosine kinase (100%) (view alignment) MET (P08581) - HUMAN 1R0P_A 60.26 9.0E-111 1.8Å KSA 2003-10-07
Protein tyrosine kinase (100%) (view alignment) MET (P08581) - HUMAN 3QTI_A 60.26 1.0E-110 2Å 3QT 2011-07-06
Protein tyrosine kinase (100%) (view alignment) IGF1R (P08069) - HUMAN 3NW5_A 37.29 4.0E-54 2.14Å LGX 2010-07-28
Protein tyrosine kinase (100%) (view alignment) IGF1R (P08069) - HUMAN 2OJ9_A 37.29 4.0E-54 2Å BMI 2007-05-01
Protein tyrosine kinase (100%) (view alignment) MET (P08581) - HUMAN 4XYF_A 61.74 1.0E-109 1.85Å 44X 2015-03-11
Protein tyrosine kinase (98%) (view alignment) ABL1 (P00519) - HUMAN 6BL8_B 38.46 4.0E-52 2.5Å PVB 2018-03-07
Protein tyrosine kinase (100%) (view alignment) INSR (P06213) Irs2 (P81122) HUMAN 3BU3_A 37.81 8.0E-52 1.65Å - 2008-02-19
Protein tyrosine kinase (100%) (view alignment) MET (P08581) - HUMAN 5YA5_A 60.93 7.0E-108 1.89Å 6TD 2018-07-04
Protein tyrosine kinase (98%) (view alignment) FGFR2 (P21802) - HUMAN 4J98_A 38.71 3.0E-52 2.3Å - 2013-08-07
Protein tyrosine kinase (100%) (view alignment) MERTK (Q12866) - HUMAN 2P0C_A 40.48 3.0E-61 2.4Å ANP 2007-05-08
Protein tyrosine kinase (100%) (view alignment) IGF1R (P08069) - HUMAN 3F5P_R 37.93 6.0E-54 2.9Å 741 2008-12-30
Protein tyrosine kinase (100%) (view alignment) MET (P08581) - HUMAN 4EEV_A 60.93 9.0E-108 1.51Å L1X 2013-04-10
Protein tyrosine kinase (100%) (view alignment) IGF1R (P08069) - HUMAN 5HZN_G 37.59 1.0E-53 2.2Å 66A MES 2016-04-06
Protein tyrosine kinase (100%) (view alignment) MERTK (Q12866) - HUMAN 4MH7_B 40.48 3.0E-61 2.51Å - 2014-05-21
Protein tyrosine kinase (100%) (view alignment) INSR (P06213) - HUMAN 1GAG_A 37.81 4.0E-52 2.7Å - 2001-01-17
Protein tyrosine kinase (100%) (view alignment) IGF1R (P08069) - HUMAN 1M7N_A 37.93 2.0E-53 2.7Å - 2003-01-07
Protein tyrosine kinase (100%) (view alignment) MET (P08581) - HUMAN 3EFJ_A 61.74 1.0E-109 2.6Å MT3 2008-10-07
Protein tyrosine kinase (100%) (view alignment) MERTK (Q12866) - HUMAN 3TCP_A 40.48 3.0E-61 2.69Å CKJ 2012-06-20
Protein tyrosine kinase (100%) (view alignment) Tyro3 (P55144) - MOUSE 3QUP_A 41.61 3.0E-61 1.72Å LUN 2011-12-21
Protein tyrosine kinase (100%) (view alignment) MERTK (Q12866) - HUMAN 5TC0_B 40 3.0E-61 2.24Å - 2017-01-25
Protein tyrosine kinase (100%) (view alignment) PTK2B (Q14289) - HUMAN 5TOB_A 37.64 2.0E-52 2.117Å YAM 2017-11-29
Protein tyrosine kinase (100%) (view alignment) MET (P08581) - HUMAN 5HOA_A 59.93 2.0E-110 2.14Å 63K 2016-11-23
Protein tyrosine kinase (100%) (view alignment) MET (P08581) - HUMAN 3F66_B 61.62 3.0E-109 1.4Å IHX 2008-12-23
Protein tyrosine kinase (100%) (view alignment) IGF1R (P08069) - HUMAN 5HZN_H 37.59 1.0E-53 2.2Å 66A MES 2016-04-06
Protein tyrosine kinase (100%) (view alignment) MET (P08581) - HUMAN 5UAF_A 60.63 2.0E-113 2.25Å 84P 2017-05-31
Protein tyrosine kinase (100%) (view alignment) MET (P08581) - HUMAN 3RHK_B 60.93 8.0E-108 1.94Å M97 2011-04-27
Protein tyrosine kinase (100%) (view alignment) MET (P08581) - HUMAN 4R1V_A 61.51 3.0E-106 1.2Å 3E8 2015-03-18
Protein tyrosine kinase (100%) (view alignment) MERTK (Q12866) - HUMAN 3BPR_A 40.48 3.0E-61 2.8Å OLP 2008-01-29
Protein tyrosine kinase (100%) (view alignment) IGF1R (P08069) - HUMAN 2ZM3_D 37.93 6.0E-54 2.27Å 575 2008-06-10
Protein tyrosine kinase (100%) (view alignment) MERTK (Q12866) - HUMAN 5K0K_A 40.48 3.0E-61 2.545Å 6Q1 2017-01-11
Protein tyrosine kinase (100%) (view alignment) IGF1R (P08069) - HUMAN 1P4O_A 37.59 3.0E-53 1.5Å - 2003-04-29
Protein tyrosine kinase (100%) (view alignment) MET (P08581) - HUMAN 3CD8_A 61.74 1.0E-109 2Å L5G 2008-04-29
Protein tyrosine kinase (100%) (view alignment) MERTK (Q12866) - HUMAN 3BRB_A 40.48 3.0E-61 1.9Å ADP 2008-01-22
Protein tyrosine kinase (100%) (view alignment) IGF1R (P08069) - HUMAN 3LVP_A 37.93 3.0E-54 3Å EPE PDR 2010-07-21
Protein tyrosine kinase (100%) (view alignment) MET (P08581) - HUMAN 3LQ8_A 61.49 2.0E-108 2.02Å 88Z 2010-05-19
Protein tyrosine kinase (98%) (view alignment) FGFR2 (P21802) - HUMAN 4J97_C 38.35 9.0E-52 2.548Å ACP 2013-08-07
Protein tyrosine kinase (100%) (view alignment) INSR (P06213) - HUMAN 1IRK_A 37.81 4.0E-52 2.1Å - 1995-02-27
Protein tyrosine kinase (100%) (view alignment) IGF1R (P08069) - HUMAN 2ZM3_A 37.93 6.0E-54 2.27Å 575 2008-06-10
Protein tyrosine kinase (100%) (view alignment) MET (P08581) - HUMAN 3U6I_A 61.74 1.0E-109 2.1Å 044 2012-02-22
Protein tyrosine kinase (100%) (view alignment) INSR (P06213) Irs2 (P81122) HUMAN 3BU5_A 37.81 8.0E-52 2.1Å ATP 2008-02-19
Protein tyrosine kinase (100%) (view alignment) IGF1R (P08069) - HUMAN 1JQH_A 37.93 6.0E-54 2.1Å ANP 2002-04-19
Protein tyrosine kinase (100%) (view alignment) ABL2 (P42684) - HUMAN 3GVU_A 38.99 2.0E-52 2.05Å STI 2009-04-21
Protein tyrosine kinase (100%) (view alignment) MET (P08581) - HUMAN 3ZZE_A 61.36 1.0E-107 1.74Å 6XP 2011-09-14
Protein tyrosine kinase (100%) (view alignment) IGF1R (P08069) - HUMAN 3F5P_T 37.93 6.0E-54 2.9Å 741 2008-12-30
Protein tyrosine kinase (100%) (view alignment) FGFR2 (P21802) - HUMAN 1GJO_A 36.33 4.0E-52 2.4Å - 2003-08-15
Protein tyrosine kinase (100%) (view alignment) INSR (P06213) PTPN1 (P18031) HUMAN 2B4S_D 37.81 8.0E-52 2.3Å - 2005-11-15
Protein tyrosine kinase (100%) (view alignment) Abl2 (Q4JIM5) - MOUSE 4XLI_A 38.99 3.0E-52 2.5Å 1N1 2015-04-01
Protein tyrosine kinase (98%) (view alignment) Abl1 (P00520) - MOUSE 3DK7_B 38.85 6.0E-53 2.01Å SX7 2008-07-29
Protein tyrosine kinase (100%) (view alignment) MET (P08581) - HUMAN 5HLW_A 61.74 7.0E-110 1.97Å 62E 2016-11-23
Protein tyrosine kinase (100%) (view alignment) PTK2B (Q14289) - HUMAN 3H3C_A 37.64 2.0E-52 2Å P1E 2009-05-26
Protein tyrosine kinase (100%) (view alignment) IGF1R (P08069) - HUMAN 5HZN_F 37.59 1.0E-53 2.2Å 66A MES 2016-04-06
Protein tyrosine kinase (100%) (view alignment) IGF1R (P08069) - HUMAN 3F5P_D 37.93 6.0E-54 2.9Å 741 2008-12-30
Protein tyrosine kinase (100%) (view alignment) MET (P08581) - HUMAN 4R1Y_A 61.64 6.0E-107 2Å 3EH 2015-03-18
Protein tyrosine kinase (100%) (view alignment) MET (P08581) - HUMAN 4KNB_C 62.46 2.0E-106 2.4Å 1RU 2014-04-30
Protein tyrosine kinase (98%) (view alignment) Abl1 (P00520) - MOUSE 3DK6_B 39.23 5.0E-53 2.016Å SX7 2008-07-29
Protein tyrosine kinase (100%) (view alignment) MET (P08581) - HUMAN 3ZC5_A 61.36 1.0E-107 2.2Å W9Z 2013-11-27
Protein tyrosine kinase (100%) (view alignment) MERTK (Q12866) - HUMAN 5TD2_B 40.69 1.0E-61 2.68Å - 2017-01-25
Protein tyrosine kinase (100%) (view alignment) IGF1R (P08069) - HUMAN 3F5P_I 37.93 6.0E-54 2.9Å 741 2008-12-30
Protein tyrosine kinase (100%) (view alignment) MET (P08581) - HUMAN 3CE3_A 60.26 8.0E-111 2.4Å 1FN 2008-08-26
Protein tyrosine kinase (100%) (view alignment) IGF1R (P08069) - HUMAN 3LW0_D 37.59 1.0E-53 1.79Å CCX 2010-09-29
Protein tyrosine kinase (99%) (view alignment) IGF1R (P08069) - HUMAN 3QQU_C 38.6 5.0E-53 2.9Å 01P 2011-04-20
Protein tyrosine kinase (100%) (view alignment) IGF1R (P08069) - HUMAN 3NW7_A 37.29 4.0E-54 2.11Å LGV 2010-07-28
Protein tyrosine kinase (98%) (view alignment) FGFR2 (P21802) - HUMAN 4J97_A 38.35 9.0E-52 2.548Å ACP 2013-08-07
Protein tyrosine kinase (100%) (view alignment) MET (P08581) - HUMAN 3ZBX_A 61.36 1.0E-107 2.2Å 6XE 2013-11-27
Protein tyrosine kinase (100%) (view alignment) IGF1R (P08069) - HUMAN 5FXS_A 37.59 4.0E-53 1.9Å OZN 2016-10-19
Protein tyrosine kinase (98%) (view alignment) Abl1 (P00520) - MOUSE 3DK3_B 38.46 4.0E-52 2.02Å SX7 2008-07-29
Protein tyrosine kinase (100%) (view alignment) IGF1R (P08069) - HUMAN 3LVP_D 37.93 3.0E-54 3Å PDR 2010-07-21
Protein tyrosine kinase (100%) (view alignment) MET (P08581) - HUMAN 3CCN_A 61.74 1.0E-109 1.9Å LKG 2008-04-29
Protein tyrosine kinase (98%) (view alignment) INSR (P06213) - HUMAN 3ETA_A 38.72 6.0E-52 2.6Å 351 2009-05-26
Protein tyrosine kinase (100%) (view alignment) INSR (P06213) - HUMAN 1I44_A 37.81 8.0E-52 2.4Å ACP 2001-03-07
Protein tyrosine kinase (100%) (view alignment) MET (P08581) - HUMAN 2WGJ_A 61.36 1.0E-107 2Å VGH 2009-06-02
Protein tyrosine kinase (100%) (view alignment) MET (P08581) - HUMAN 5UAB_A 60.63 2.0E-113 1.9Å 84M 2017-05-31
Protein tyrosine kinase (100%) (view alignment) MET (P08581) - HUMAN 4KNB_B 62.46 2.0E-106 2.4Å 1RU 2014-04-30
Protein tyrosine kinase (100%) (view alignment) PTK2B (Q14289) - HUMAN 4H1M_A 37.64 2.0E-52 1.99Å 0YJ 2012-11-28
Protein tyrosine kinase (100%) (view alignment) MET (P08581) - HUMAN 3Q6W_A 61.36 1.0E-107 1.75Å Q6W 2011-01-19
Protein tyrosine kinase (100%) (view alignment) IGF1R (P08069) - HUMAN 3I81_A 37.29 5.0E-54 2.08Å EBI 2009-12-22
Protein tyrosine kinase (100%) (view alignment) IGF1R (P08069) - HUMAN 1JQH_B 37.93 6.0E-54 2.1Å ANP 2002-04-19
Protein tyrosine kinase (100%) (view alignment) MST1R (Q04912) - HUMAN 3PLS_A 100 0 2.24Å ANP 2010-11-24
Protein tyrosine kinase (100%) (view alignment) MERTK (Q12866) - HUMAN 4MH7_A 40.48 3.0E-61 2.51Å MH7 2014-05-21
Protein tyrosine kinase (98%) (view alignment) FGFR2 (P21802) - HUMAN 2PZP_B 38.35 9.0E-52 2.4Å ACP 2007-09-25
Protein tyrosine kinase (100%) (view alignment) MET (P08581) - HUMAN 4GG7_A 60.93 7.0E-108 2.27Å 0J8 2012-10-03
Protein tyrosine kinase (98%) (view alignment) FGFR2 (P21802) - HUMAN 2PVF_A 37.72 1.0E-52 1.8Å ACP 2007-09-25
Protein tyrosine kinase (100%) (view alignment) IGF1R (P08069) - HUMAN 3LW0_A 37.59 1.0E-53 1.79Å CCX 2010-09-29
Protein tyrosine kinase (100%) (view alignment) MET (P08581) - HUMAN 4AOI_A 61.36 1.0E-107 1.8Å 4K0 2012-09-26
Protein tyrosine kinase (98%) (view alignment) ABL1 (P00519) - HUMAN 6BL8_A 38.46 4.0E-52 2.5Å PVB 2018-03-07
Protein tyrosine kinase (100%) (view alignment) MET (P08581) - HUMAN 2WKM_A 61.36 1.0E-107 2.1Å PFY 2010-08-25
Protein tyrosine kinase (100%) (view alignment) MET (P08581) - HUMAN 4IWD_A 61.28 2.0E-108 1.99Å 1JC 2013-12-11
Protein tyrosine kinase (100%) (view alignment) ABL2 (P42684) - HUMAN 2XYN_A 38.99 2.0E-52 2.81Å VX6 2010-12-01
Protein tyrosine kinase (100%) (view alignment) INSR (P06213) Sh2b2 (Q9Z200) HUMAN 1RQQ_A 37.81 8.0E-52 2.6Å - 2003-12-30
Protein tyrosine kinase (100%) (view alignment) MET (P08581) - HUMAN 3DKF_A 59.62 8.0E-111 1.8Å SX8 2009-07-07
Protein tyrosine kinase (98%) (view alignment) FGFR2 (P21802) - HUMAN 2Q0B_A 38.35 8.0E-52 2.9Å ACP 2007-09-25
Protein tyrosine kinase (100%) (view alignment) MET (P08581) - HUMAN 3CTH_A 60.26 8.0E-111 2.3Å 319 2008-06-10
Protein tyrosine kinase (100%) (view alignment) MERTK (Q12866) - HUMAN 4MHA_B 40.48 3.0E-61 2.59Å 4MH 2014-05-21
Protein tyrosine kinase (100%) (view alignment) ABL2 (P42684) - HUMAN 2XYN_B 38.99 2.0E-52 2.81Å VX6 2010-12-01
Protein tyrosine kinase (100%) (view alignment) PTK2B (Q14289) - HUMAN 3FZT_A 37.64 2.0E-52 1.95Å 4JZ 2009-03-31
Protein tyrosine kinase (100%) (view alignment) MERTK (Q12866) - HUMAN 2P0C_B 40.48 3.0E-61 2.4Å ANP 2007-05-08
Protein tyrosine kinase (100%) (view alignment) ABL2 (P42684) - HUMAN 3HMI_A 38.99 2.0E-52 1.65Å DKI 2009-07-07
Protein tyrosine kinase (100%) (view alignment) IGF1R (P08069) - HUMAN 4D2R_A 37.93 5.0E-54 2.1Å DYK 2015-04-22
Protein tyrosine kinase (100%) (view alignment) IGF1R (P08069) - HUMAN 5HZN_D 37.59 1.0E-53 2.2Å 66A MES 2016-04-06
Protein tyrosine kinase (100%) (view alignment) PTK2B (Q14289) - HUMAN 3CC6_A 37.64 2.0E-52 1.6Å - 2008-03-11
Protein tyrosine kinase (100%) (view alignment) MET (P08581) - HUMAN 3CTJ_A 60.26 8.0E-111 2.5Å 320 2008-06-10
Protein tyrosine kinase (100%) (view alignment) MERTK (Q12866) - HUMAN 4M3Q_B 40.48 3.0E-61 2.71Å 24K 2013-11-27
Protein tyrosine kinase (100%) (view alignment) IGF1R (P08069) - HUMAN 3F5P_K 37.93 6.0E-54 2.9Å 741 2008-12-30
Protein tyrosine kinase (100%) (view alignment) MERTK (Q12866) - HUMAN 3BPR_B 40.48 3.0E-61 2.8Å OLP 2008-01-29
Protein tyrosine kinase (98%) (view alignment) INSR (P06213) - HUMAN 3ETA_B 38.72 6.0E-52 2.6Å 351 2009-05-26
Protein tyrosine kinase (100%) (view alignment) FGFR2 (P21802) - HUMAN 2PSQ_B 35.91 7.0E-52 2.4Å - 2007-09-25
Protein tyrosine kinase (100%) (view alignment) MET (P08581) - HUMAN 5UAD_A 60.63 2.0E-113 2.25Å 84P 2017-05-31
Protein tyrosine kinase (100%) (view alignment) MET (P08581) - HUMAN 3EFK_B 61.74 1.0E-109 2.2Å MT4 2008-10-07
Protein tyrosine kinase (100%) (view alignment) IGF1R (P08069) - HUMAN 3F5P_H 37.93 6.0E-54 2.9Å 741 2008-12-30
Protein tyrosine kinase (100%) (view alignment) MERTK (Q12866) - HUMAN 3BRB_B 40.48 3.0E-61 1.9Å ADP 2008-01-22
Protein tyrosine kinase (100%) (view alignment) MET (P08581) - HUMAN 3C1X_A 60.26 4.0E-111 2.17Å CKK 2008-03-18
Protein tyrosine kinase (100%) (view alignment) Tyro3 (P55144) - MOUSE 4FF8_A 41.61 3.0E-61 2.24Å 14S 2013-03-13
Protein tyrosine kinase (100%) (view alignment) MET (P08581) - HUMAN 3R7O_A 61.36 1.0E-107 2.3Å M61 2012-02-01
Protein tyrosine kinase (100%) (view alignment) MET (P08581) - HUMAN 4DEI_A 61.74 1.0E-109 2.05Å 0JL 2012-05-30
Protein tyrosine kinase (100%) (view alignment) MERTK (Q12866) - HUMAN 5TC0_A 40 3.0E-61 2.24Å 79Y 2017-01-25
Protein tyrosine kinase (98%) (view alignment) FGFR2 (P21802) - HUMAN 2PZ5_A 38.35 7.0E-52 2.4Å ACP 2007-09-25
Protein tyrosine kinase (100%) (view alignment) IGF1R (P08069) - HUMAN 3F5P_F 37.93 6.0E-54 2.9Å 741 2008-12-30
Protein tyrosine kinase (100%) (view alignment) MET (P08581) - HUMAN 3VW8_A 60.26 2.0E-109 1.9Å DF6 2013-08-14
Protein tyrosine kinase (100%) (view alignment) INSR (P06213) - HUMAN 1IR3_A 37.81 4.0E-52 1.9Å ANP 1998-01-07
Sema domain (100%), IPT/TIG domain (100%) (view alignment) MST1R (Q04912) MST1 (P26927) HUMAN 4QT8_A 100 0 2.996Å NAG 2014-09-17
Protein tyrosine kinase (100%) (view alignment) INSR (P06213) IRS1 (P35568) HUMAN 2Z8C_A 37.81 3.0E-52 3.25Å S91 2008-08-12
Protein tyrosine kinase (100%) (view alignment) MET (P08581) - HUMAN 3DKC_A 59.62 8.0E-111 1.52Å ATP 2009-07-07
Protein tyrosine kinase (100%) (view alignment) MET (P08581) - HUMAN 5EYC_A 61.74 1.0E-109 1.8Å 5SZ 2016-02-10
Protein tyrosine kinase (100%) (view alignment) MET (P08581) - HUMAN 4DEG_A 61.74 1.0E-109 2Å 0JJ 2012-05-30
Protein tyrosine kinase (100%) (view alignment) MERTK (Q12866) - HUMAN 5U6C_A 40.48 1.0E-61 2.1Å 7YS 2017-07-26
Protein tyrosine kinase (100%) (view alignment) MET (P08581) - HUMAN 3RHK_A 60.93 8.0E-108 1.94Å M97 2011-04-27
Protein tyrosine kinase (100%) (view alignment) MERTK (Q12866) - HUMAN 3BPR_D 40.48 3.0E-61 2.8Å OLP 2008-01-29
Protein tyrosine kinase (100%) (view alignment) PTK2B (Q14289) - HUMAN 3FZS_A 37.64 2.0E-52 1.75Å B96 2009-03-31
Protein tyrosine kinase (100%) (view alignment) IGF1R (P08069) - HUMAN 5HZN_B 37.59 1.0E-53 2.2Å 66A MES 2016-04-06
Protein tyrosine kinase (100%) (view alignment) MET (P08581) - HUMAN 5DG5_B 60.93 8.0E-108 2.6Å 5B4 2016-08-31
Protein tyrosine kinase (100%) (view alignment) PTK2B (Q14289) - HUMAN 4H1J_A 37.64 2.0E-52 2Å 0YH 2012-11-28
Protein tyrosine kinase (100%) (view alignment) MET (P08581) - HUMAN 3DKG_A 59.94 2.0E-111 1.909Å SX8 2009-07-07
Protein tyrosine kinase (100%) (view alignment) MET (P08581) - HUMAN 5HNI_X 60.26 9.0E-111 1.71Å 63B 2016-11-23
Protein tyrosine kinase (100%) (view alignment) MET (P08581) - HUMAN 3EFK_A 61.74 1.0E-109 2.2Å MT4 2008-10-07
Protein tyrosine kinase (100%) (view alignment) MET (P08581) - HUMAN 3Q6U_A 61.36 1.0E-107 1.45Å - 2011-01-19
Protein tyrosine kinase (100%) (view alignment) PTK2B (Q14289) - HUMAN 3ET7_A 37.64 2.0E-52 2.7Å 349 2009-06-23
Protein tyrosine kinase (100%) (view alignment) MERTK (Q12866) - HUMAN 5K0X_A 40.48 3.0E-61 2.23Å K0X 2017-02-22
Protein tyrosine kinase (100%) (view alignment) MET (P08581) - HUMAN 5HOR_A 59.93 5.0E-110 2.2Å 63K 2016-11-23
Protein tyrosine kinase (100%) (view alignment) INSR (P06213) - HUMAN 4XLV_A 37.81 5.0E-52 2.3Å ACP 2015-03-25
Protein tyrosine kinase (100%) (view alignment) MET (P08581) - HUMAN 5DG5_A 60.93 8.0E-108 2.6Å 5B4 2016-08-31
Protein tyrosine kinase (100%) (view alignment) MET (P08581) - HUMAN 3EFJ_B 61.74 1.0E-109 2.6Å MT3 2008-10-07
Protein tyrosine kinase (100%) (view alignment) INSR (P06213) PTPN1 (P18031) HUMAN 2B4S_B 37.81 8.0E-52 2.3Å - 2005-11-15
Protein tyrosine kinase (100%) (view alignment) INSR (P06213) GRB14 (Q14449) HUMAN 2AUH_A 37.81 8.0E-52 3.2Å - 2005-11-01
Protein tyrosine kinase (100%) (view alignment) IGF1R (P08069) - HUMAN 3F5P_S 37.93 6.0E-54 2.9Å 741 2008-12-30
Protein tyrosine kinase (100%) (view alignment) PTK2B (Q14289) - HUMAN 3FZP_A 37.64 2.0E-52 2.1Å AGS 2009-03-31
Protein tyrosine kinase (100%) (view alignment) MET (P08581) - HUMAN 2RFN_A 61.74 1.0E-109 2.5Å AM7 2007-11-06
Protein tyrosine kinase (100%) (view alignment) MERTK (Q12866) - HUMAN 5K0K_B 40.48 3.0E-61 2.545Å 6Q1 2017-01-11
Protein tyrosine kinase (100%) (view alignment) PTK2B (Q14289) - HUMAN 3FZR_A 37.64 2.0E-52 2.7Å 3JZ 2009-03-31
Protein tyrosine kinase (100%) (view alignment) IGF1R (P08069) - HUMAN 2ZM3_B 37.93 6.0E-54 2.27Å 575 2008-06-10
Protein tyrosine kinase (100%) (view alignment) MET (P08581) - HUMAN 3ZCL_A 61.36 1.0E-107 1.4Å 5TF 2013-11-27
Protein tyrosine kinase (100%) (view alignment) MET (P08581) - HUMAN 4MXC_A 60.93 7.0E-108 1.63Å DWF 2014-10-15
Protein tyrosine kinase (100%) (view alignment) IGF1R (P08069) - HUMAN 3O23_A 37.93 4.0E-54 2.1Å MQY 2011-05-04
Protein tyrosine kinase (100%) (view alignment) IGF1R (P08069) - HUMAN 3LVP_C 37.93 3.0E-54 3Å PDR 2010-07-21
Protein tyrosine kinase (98%) (view alignment) FGFR3 (P22607) - HUMAN 4K33_A 39.51 1.0E-52 2.34Å ACP 2013-09-11
Protein tyrosine kinase (100%) (view alignment) IGF1R (P08069) - HUMAN 3NW6_A 37.29 4.0E-54 2.2Å LGW 2010-07-28
Protein tyrosine kinase (100%) (view alignment) MET (P08581) - HUMAN 3QTI_B 60.26 1.0E-110 2Å 3QT 2011-07-06
Protein tyrosine kinase (98%) (view alignment) FGFR2 (P21802) - HUMAN 4J98_B 38.71 3.0E-52 2.3Å ACP 2013-08-07
Protein tyrosine kinase (100%) (view alignment) MET (P08581) - HUMAN 3L8V_A 60.26 8.0E-111 2.4Å L8V 2010-05-05
Protein tyrosine kinase (100%) (view alignment) MET (P08581) - HUMAN 4KNB_A 62.46 2.0E-106 2.4Å 1RU 2014-04-30
Protein tyrosine kinase (100%) (view alignment) MET (P08581) - HUMAN 2WD1_A 61.64 6.0E-107 2Å ZZY 2009-04-28
Protein tyrosine kinase (100%) (view alignment) MERTK (Q12866) - HUMAN 5K0X_B 40.48 3.0E-61 2.23Å K0X 2017-02-22
Protein tyrosine kinase (100%) (view alignment) MET (P08581) - HUMAN 4GG5_A 60.93 7.0E-108 2.42Å 0J3 2012-10-03
Protein tyrosine kinase (100%) (view alignment) MET (P08581) - HUMAN 3A4P_A 60.26 1.0E-110 2.48Å DFQ 2010-02-16
Sema domain (100%), IPT/TIG domain (100%) (view alignment) MST1R (Q04912) MST1 (P26927) HUMAN 4QT8_B 100 0 2.996Å NAG BMA 2014-09-17
Protein tyrosine kinase (100%) (view alignment) INSR (P06213) Sh2b2 (Q9Z200) HUMAN 1RQQ_B 37.81 8.0E-52 2.6Å - 2003-12-30
Protein tyrosine kinase (100%) (view alignment) AXL (P30530) - HUMAN 5U6B_C 40.8 9.0E-61 2.84Å 7YS 2017-07-26
Protein tyrosine kinase (100%) (view alignment) IGF1R (P08069) - HUMAN 3D94_A 37.72 1.0E-52 2.3Å D94 2008-07-29
Protein tyrosine kinase (100%) (view alignment) PTK2B (Q14289) - HUMAN 3FZO_A 37.64 2.0E-52 2.2Å - 2009-03-31
Protein tyrosine kinase (100%) (view alignment) IGF1R (P08069) - HUMAN 5FXQ_A 37.93 5.0E-54 2.3Å GD5 2016-10-19
Protein tyrosine kinase (100%) (view alignment) IGF1R (P08069) - HUMAN 3LW0_C 37.59 1.0E-53 1.79Å CCX 2010-09-29
Protein tyrosine kinase (100%) (view alignment) IGF1R (P08069) - HUMAN 5HZN_C 37.59 1.0E-53 2.2Å 66A MES 2016-04-06
Protein tyrosine kinase (100%) (view alignment) AXL (P30530) - HUMAN 5U6B_A 40.8 9.0E-61 2.84Å 7YS 2017-07-26
Protein tyrosine kinase (100%) (view alignment) IGF1R (P08069) - HUMAN 5HZN_E 37.59 1.0E-53 2.2Å 66A MES 2016-04-06
Protein tyrosine kinase (99%) (view alignment) IGF1R (P08069) - HUMAN 3QQU_B 38.6 5.0E-53 2.9Å 01P 2011-04-20
Protein tyrosine kinase (100%) (view alignment) MET (P08581) - HUMAN 2G15_A 60.93 8.0E-108 2.15Å - 2006-03-21
Protein tyrosine kinase (100%) (view alignment) MERTK (Q12866) - HUMAN 4M3Q_A 40.48 3.0E-61 2.71Å 24K 2013-11-27
Protein tyrosine kinase (98%) (view alignment) FGFR2 (P21802) - HUMAN 4J97_D 38.35 9.0E-52 2.548Å ACP 2013-08-07
Protein tyrosine kinase (100%) (view alignment) MET (P08581) - HUMAN 5EOB_A 60.93 7.0E-108 1.75Å 5QQ 2016-10-19
Protein tyrosine kinase (98%) (view alignment) FGFR2 (P21802) - HUMAN 2Q0B_B 38.35 8.0E-52 2.9Å ACP 2007-09-25
Protein tyrosine kinase (98%) (view alignment) FGFR2 (P21802) - HUMAN 3CLY_A 37.72 1.0E-52 2Å ACP 2009-02-03
Protein tyrosine kinase (98%) (view alignment) Abl1 (P00520) - MOUSE 3DK6_A 39.23 5.0E-53 2.016Å SX7 2008-07-29
Protein tyrosine kinase (100%) (view alignment) IGF1R (P08069) - HUMAN 3F5P_A 37.93 6.0E-54 2.9Å 741 2008-12-30
Protein tyrosine kinase (100%) (view alignment) IGF1R (P08069) - HUMAN 1P4O_B 37.59 3.0E-53 1.5Å - 2003-04-29
Protein tyrosine kinase (100%) (view alignment) MET (P08581) - HUMAN 4XMO_A 61.74 1.0E-109 1.75Å 46G 2015-03-11
Protein tyrosine kinase (98%) (view alignment) FGFR2 (P21802) - HUMAN 4J97_B 38.35 9.0E-52 2.548Å ACP 2013-08-07
Protein tyrosine kinase (100%) (view alignment) MET (P08581) - HUMAN 5HNI_Y 60.26 9.0E-111 1.71Å 63B 2016-11-23
Protein tyrosine kinase (100%) (view alignment) MET (P08581) - HUMAN 5EYD_A 61.74 1.0E-109 1.85Å 5T1 2016-02-10
Protein tyrosine kinase (100%) (view alignment) IGF1R (P08069) - HUMAN 3LVP_B 37.93 3.0E-54 3Å PDR 2010-07-21
Protein tyrosine kinase (100%) (view alignment) MET (P08581) - HUMAN 5HTI_A 60.93 7.0E-108 1.66Å 66L 2017-02-01
Protein tyrosine kinase (98%) (view alignment) Abl1 (P00520) - MOUSE 3DK3_A 38.46 4.0E-52 2.02Å SX7 2008-07-29
Protein tyrosine kinase (100%) (view alignment) MET (P08581) - HUMAN 2RFN_B 61.74 1.0E-109 2.5Å AM7 2007-11-06
Protein tyrosine kinase (100%) (view alignment) MET (P08581) - HUMAN 2RFS_A 61.74 1.0E-109 2.2Å AM8 2007-11-06
Protein tyrosine kinase (100%) (view alignment) MET (P08581) - HUMAN 4AP7_A 61.36 1.0E-107 1.75Å F47 2012-09-26
Protein tyrosine kinase (100%) (view alignment) ABL2 (P42684) - HUMAN 2XYN_C 38.99 2.0E-52 2.81Å VX6 2010-12-01
Protein tyrosine kinase (100%) (view alignment) IGF1R (P08069) - HUMAN 3F5P_J 37.93 6.0E-54 2.9Å 741 2008-12-30
Protein tyrosine kinase (100%) (view alignment) IGF1R (P08069) - HUMAN 3F5P_C 37.93 6.0E-54 2.9Å 741 2008-12-30
Protein tyrosine kinase (100%) (view alignment) IGF1R (P08069) - HUMAN 2ZM3_C 37.93 6.0E-54 2.27Å 575 2008-06-10
Protein tyrosine kinase (99%) (view alignment) IGF1R (P08069) - HUMAN 3QQU_D 38.6 5.0E-53 2.9Å 01P 2011-04-20
Protein tyrosine kinase (98%) (view alignment) - 4UEU_A 41.06 1.0E-54 2.95Å ACP 2015-02-18