Molecular Target Synopsis
Overview
Domains and Structures
Drugs and Clinical Candidates
Druggability
Chemistry
Ligand Efficiency Plot
Pathways
Family Cladogram
Interaction Network
Gene Expression
Gene Copy Number Variation
RNAi
Mutations
Germline Genetics

petA (Q02762) - Overview - Molecular Target Synopsis

Protein


petA, Ubiquinol-cytochrome c reductase iron-sulfur subunit
Enzyme Classification 7.1.1.8
UniProt Q02762

Also Known as UCRI_RHOSH, petA, fbcF

Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis. The main subunits of complex b-c1 are: cytochrome b, cytochrome c1 and the Rieske protein.

5KLI
RHODOBACTER SPHAEROIDES BC1 WITH STIGMATELLIN AND ANTIMYCIN
RCSB/PDB
Inspect Structure
See all 3D Structures for petA

Isoforms / Transcripts (Protein Coding)


Protein Length Ensembl Gene Ensembl Transcript Ensembl Protein Uniprot Isoform
187Q02762-1

Sub-cellular localization


UniProt: petA is active in the following subcellular-locations: cell membrane.
GO terms: petA is active in the following subcellular-locations: integral component of membrane, plasma membrane.



UniProt
GO terms

Gene Copy Number Variation


In COSMIC - Cell Lines Project petA has gain in 0 cell-lines, loss in 0 cell-lines and no signal in 0 cell-lines. (see details)

3D Structures


For petA there are:
12 structures (36 chains) solved
0 are solved in complex with at least one small molecule ligand



(see details)
Molecular Target 3D Synopsis

Screening and Chemistry


petA has been screened with compounds ( bioactivities). (see details)