Molecular Target Synopsis
Overview
Domains and Structures
Drugs and Clinical Candidates
Druggability
Chemistry
Ligand Efficiency Plot
Pathways
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Interaction Network
Gene Expression
Gene Copy Number Variation
RNAi
Mutations
Germline Genetics

petC (Q02760) - Overview - Molecular Target Synopsis

Protein


petC, Cytochrome c1
UniProt Q02760

Also Known as CY1_RHOSH, petC, fbcC

Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis. c1 functions as an electron donor to cytochrome c. The main subunits of complex b-c1 are: cytochrome b, cytochrome c1 and the Rieske protein.

5KKZ
RHODOBACTER SPHAEROIDES BC1 WITH FAMOXADONE
RCSB/PDB
Inspect Structure
See all 3D Structures for petC

Isoforms / Transcripts (Protein Coding)


Protein Length Ensembl Gene Ensembl Transcript Ensembl Protein Uniprot Isoform
285Q02760-1

Sub-cellular localization


UniProt: petC is active in the following subcellular-locations: cell membrane.
GO terms: petC is active in the following subcellular-locations: integral component of membrane, plasma membrane, respirasome.



UniProt
GO terms

Gene Copy Number Variation


In COSMIC - Cell Lines Project petC has gain in 0 cell-lines, loss in 0 cell-lines and no signal in 0 cell-lines. (see details)

3D Structures


For petC there are:
6 structures (30 chains) solved
6 are solved in complex with at least one small molecule ligand



(see details)
Molecular Target 3D Synopsis