Molecular Target Synopsis
Overview
Domains and Structures
Drugs and Clinical Candidates
Druggability
Chemistry
Ligand Efficiency Plot
Pathways
Family Cladogram
Interaction Network
Gene Expression
Gene Copy Number Variation
RNAi
Mutations
Germline Genetics

RPA49 (Q01080) - Domains And Structures - Molecular Target Synopsis

Click Here to View Molecular Target 3D Synopsis

Select a homology cutoff:
Structural Sequence Similarity Matches
Domains Covered Gene Name (Uniprot) Solved in Complex with Organism PDB Chain Identity E-Value Resolution Ligands Release Date
A49-like RNA polymerase I associated factor (100%) (view alignment) RPA49 (Q01080) RPC10 (P40422), RPB8 (P20436), RPB5 (P20434), RPC19 (P28000), RPA43 (P46669), RRN7 (P40992), RPA190 (P10964), RPA34 (P47006), RPO26 (P20435), RPA135 (P22138), RRN11 (Q04712), RPC40 (P07703), RRN6 (P32786), RPA12 (P32529), RPA14 (P50106), RPB10 (P22139) BAKER'S YEAST 5W66_M 100 0 3.9Å - 2017-07-26
A49-like RNA polymerase I associated factor (100%) (view alignment) RPA49 (Q01080) RPC10 (P40422), RPB8 (P20436), RPB5 (P20434), RPC19 (P28000), RPA43 (P46669), RPA190 (P10964), RPA34 (P47006), RPO26 (P20435), RPA135 (P22138), RPC40 (P07703), RPA12 (P32529), RPA14 (P50106), RPB10 (P22139) 6H67_M 100 0 3.6Å - 2018-08-29
A49-like RNA polymerase I associated factor (100%) (view alignment) RPA49 (Q01080) RPC10 (P40422), RPB8 (P20436), RPB5 (P20434), RPC19 (P28000), RPA43 (P46669), RPA190 (P10964), RPA34 (P47006), RPO26 (P20435), RPA135 (P22138), RPC40 (P07703), RPA12 (P32529), RPA14 (P50106), RPB10 (P22139) BAKER'S YEAST 4C3I_M 100 0 3Å - 2013-10-23
A49-like RNA polymerase I associated factor (100%) (view alignment) RPA49 (Q01080) RPC10 (P40422), RPB8 (P20436), RPB5 (P20434), RRN3 (P36070), RPC19 (P28000), RPA43 (P46669), RPA190 (P10964), RPA34 (P47006), RPO26 (P20435), RPA135 (P22138), RPC40 (P07703), RPA12 (P32529), RPA14 (P50106), RPB10 (P22139) BAKERS YEAST 5G5L_M 100 0 4.8Å - 2016-07-27
A49-like RNA polymerase I associated factor (100%) (view alignment) RPA49 (Q01080) RPC10 (P40422), RPB8 (P20436), RPB5 (P20434), RPC19 (P28000), RPA43 (P46669), RPA190 (P10964), RPA34 (P47006), RPO26 (P20435), RPA135 (P22138), RPC40 (P07703), RPA12 (P32529), RPA14 (P50106), RPB10 (P22139) BAKER'S YEAST 5M5X_M 100 0 4Å - 2016-12-21
A49-like RNA polymerase I associated factor (62%) (view alignment) RPA49 (Q01080) - YEAST 3NFI_A 100 0 1.9Å - 2010-09-08
A49-like RNA polymerase I associated factor (100%) (view alignment) RPA49 (Q01080) RPC10 (P40422), RPB8 (P20436), RPB5 (P20434), RPC19 (P28000), RPA43 (P46669), RPA190 (P10964), RPA34 (P47006), RPO26 (P20435), RPA135 (P22138), RPC40 (P07703), RPA12 (P32529), RPA14 (P50106), RPB10 (P22139) 6H68_M 100 0 4.6Å - 2018-08-29
A49-like RNA polymerase I associated factor (62%) (view alignment) RPA49 (Q01080) - YEAST 3NFI_C 100 0 1.9Å - 2010-09-08
A49-like RNA polymerase I associated factor (100%) (view alignment) RPA49 (Q01080) RPB8 (P20436), RPB5 (P20434), RPA43 (P46669), RPA190 (P10964), RPO26 (P20435), RPA135 (P22138), RRN11 (Q04712), RPC40 (P07703), RPA12 (P32529), RPA14 (P50106), RPB10 (P22139), RPC10 (P40422), RRN3 (P36070), RPC19 (P28000), RRN7 (P40992), RPA34 (P47006), RRN6 (P32786) 5OA1_M 100 0 4.4Å - 2017-07-26
A49-like RNA polymerase I associated factor (100%) (view alignment) RPA49 (Q01080) RPC10 (P40422), RPB8 (P20436), RPB5 (P20434), RPC19 (P28000), RPA43 (P46669), RRN7 (P40992), RPA190 (P10964), RPA34 (P47006), RPO26 (P20435), RPA135 (P22138), RRN11 (Q04712), RPC40 (P07703), RRN6 (P32786), RPA12 (P32529), RPA14 (P50106), RPB10 (P22139) BAKER'S YEAST 5W5Y_M 100 0 3.8Å - 2017-07-26
A49-like RNA polymerase I associated factor (62%) (view alignment) RPA49 (Q01080) - YEAST 3NFI_B 100 0 1.9Å - 2010-09-08
A49-like RNA polymerase I associated factor (100%) (view alignment) RPA49 (Q01080) RPC10 (P40422), RPB8 (P20436), RPB5 (P20434), RPC19 (P28000), RPA43 (P46669), RPA190 (P10964), RPA34 (P47006), RPO26 (P20435), RPA135 (P22138), RPC40 (P07703), RPA12 (P32529), RPA14 (P50106), RPB10 (P22139) BAKER'S YEAST 5M5Y_M 100 0 4Å - 2016-12-21
A49-like RNA polymerase I associated factor (100%) (view alignment) RPA49 (Q01080) RPC10 (P40422), RPB8 (P20436), RPB5 (P20434), RPC19 (P28000), RPA43 (P46669), RRN7 (P40992), RPA190 (P10964), RPA34 (P47006), RPO26 (P20435), RPA135 (P22138), RRN11 (Q04712), RPC40 (P07703), RRN6 (P32786), RPA12 (P32529), RPA14 (P50106), RPB10 (P22139) BAKER'S YEAST 5W65_M 100 0 4.3Å - 2017-08-02
A49-like RNA polymerase I associated factor (100%) (view alignment) RPA49 (Q01080) RPB8 (P20436), RPB5 (P20434), RPA43 (P46669), RPA190 (P10964), RPO26 (P20435), RPA135 (P22138), RRN11 (Q04712), RPC40 (P07703), RPA12 (P32529), RPA14 (P50106), RPB10 (P22139), RPC10 (P40422), RRN3 (P36070), RPC19 (P28000), RRN7 (P40992), RPA34 (P47006), RRN6 (P32786) BAKER'S YEAST 5N5Z_M 100 0 7.7Å - 2017-04-05
A49-like RNA polymerase I associated factor (100%) (view alignment) RPA49 (Q01080) RPC10 (P40422), RPB8 (P20436), RPB5 (P20434), RPC19 (P28000), RPA43 (P46669), RPA190 (P10964), RPA34 (P47006), RPO26 (P20435), RPA135 (P22138), RPC40 (P07703), RPA12 (P32529), RPA14 (P50106), RPB10 (P22139) BAKER'S YEAST 4C2M_M 100 0 2.8Å - 2013-10-23
A49-like RNA polymerase I associated factor (100%) (view alignment) RPA49 (Q01080) RPC10 (P40422), RPB8 (P20436), RPB5 (P20434), RPC19 (P28000), RPA43 (P46669), RPA190 (P10964), RPA34 (P47006), RPO26 (P20435), RPA135 (P22138), RPC40 (P07703), RPA12 (P32529), RPA14 (P50106), RPB10 (P22139) BAKER'S YEAST 4C2M_2 100 0 2.8Å - 2013-10-23
A49-like RNA polymerase I associated factor (62%) (view alignment) RPA49 (Q01080) - YEAST 3NFI_D 100 0 1.9Å - 2010-09-08
A49-like RNA polymerase I associated factor (65%) (view alignment) RPA49 (Q01080) - YEAST 3NFH_B 100 0 2.17Å - 2010-09-08
A49-like RNA polymerase I associated factor (100%) (view alignment) RPA49 (Q01080) RPB8 (P20436), RPB5 (P20434), RPA43 (P46669), RPA190 (P10964), RPO26 (P20435), RPA135 (P22138), RRN11 (Q04712), RPC40 (P07703), RPA12 (P32529), RPA14 (P50106), RPB10 (P22139), RPC10 (P40422), RRN3 (P36070), RPC19 (P28000), RRN7 (P40992), RPA34 (P47006), RRN6 (P32786) BAKER'S YEAST 5N60_M 100 0 7.7Å - 2017-04-05
A49-like RNA polymerase I associated factor (100%) (view alignment) RPA49 (Q01080) RPC10 (P40422), RPB8 (P20436), RPB5 (P20434), RPC19 (P28000), RPA43 (P46669), RRN7 (P40992), RPA190 (P10964), RPA34 (P47006), RPO26 (P20435), RPA135 (P22138), RRN11 (Q04712), RPC40 (P07703), RRN6 (P32786), RPA12 (P32529), RPA14 (P50106), RPB10 (P22139) BAKER'S YEAST 5W64_M 100 0 4.2Å - 2017-07-26
A49-like RNA polymerase I associated factor (100%) (view alignment) RPA49 (Q01080) RPC10 (P40422), RPB8 (P20436), RPB5 (P20434), RPC19 (P28000), RPA43 (P46669), RPA190 (P10964), RPA34 (P47006), RPO26 (P20435), RPA135 (P22138), RPC40 (P07703), RPA12 (P32529), RPA14 (P50106), RPB10 (P22139) BAKER'S YEAST 5M3M_M 100 0 4Å - 2016-11-23
A49-like RNA polymerase I associated factor (100%) (view alignment) RPA49 (Q01080) RPC10 (P40422), RPB8 (P20436), RPB5 (P20434), RPC19 (P28000), RPA43 (P46669), RPA190 (P10964), RPA34 (P47006), RPO26 (P20435), RPA135 (P22138), RPC40 (P07703), RPA12 (P32529), RPA14 (P50106), RPB10 (P22139) BAKER'S YEAST 5M64_M 100 0 4.6Å - 2016-12-21
A49-like RNA polymerase I associated factor (100%) (view alignment) RPA49 (Q01080) RPC10 (P40422), RPB8 (P20436), RPB5 (P20434), RPC19 (P28000), RPA43 (P46669), RPA190 (P10964), RPA34 (P47006), RPO26 (P20435), RPA135 (P22138), RPC40 (P07703), RPA12 (P32529), RPA14 (P50106), RPB10 (P22139) BAKER'S YEAST 5M5W_M 100 0 3.8Å - 2016-12-07
A49-like RNA polymerase I associated factor (100%) (view alignment) RPA49 (Q01080) RPC10 (P40422), RPB8 (P20436), RPB5 (P20434), RPC19 (P28000), RPA43 (P46669), RPA190 (P10964), RPA34 (P47006), RPO26 (P20435), RPA135 (P22138), RPC40 (P07703), RPA12 (P32529), RPA14 (P50106), RPB10 (P22139) BAKER'S YEAST 5LMX_M 100 0 4.9Å - 2017-03-22
A49-like RNA polymerase I associated factor (100%) (view alignment) RPA49 (Q01080) RPB8 (P20436), RPB5 (P20434), RPA43 (P46669), RPA190 (P10964), RPO26 (P20435), RPA135 (P22138), RRN11 (Q04712), RPC40 (P07703), RPA12 (P32529), RPA14 (P50106), RPB10 (P22139), RPC10 (P40422), RRN3 (P36070), RPC19 (P28000), RRN7 (P40992), RPA34 (P47006), RRN6 (P32786) BAKER'S YEAST 5N61_M 100 0 3.4Å - 2017-04-05
A49-like RNA polymerase I associated factor (100%) (view alignment) RPA49 (Q01080) RPC10 (P40422), RPB8 (P20436), RPB5 (P20434), RPC19 (P28000), RPA43 (P46669), RPA190 (P10964), RPA34 (P47006), RPO26 (P20435), RPA135 (P22138), RPC40 (P07703), RPA12 (P32529), RPA14 (P50106), RPB10 (P22139) BAKER'S YEAST 6HKO_M 100 0 3.42Å - 2019-04-03
A49-like RNA polymerase I associated factor (65%) (view alignment) RPA49 (Q01080) - YEAST 3NFH_A 100 0 2.17Å - 2010-09-08
A49-like RNA polymerase I associated factor (100%) (view alignment) RPA49 (Q01080) RPC10 (P40422), RPB8 (P20436), RPB5 (P20434), RPC19 (P28000), RPA43 (P46669), RPA190 (P10964), RPA34 (P47006), RPO26 (P20435), RPA135 (P22138), RPC40 (P07703), RPA12 (P32529), RPA14 (P50106), RPB10 (P22139) BAKER'S YEAST 4C3J_M 100 0 3.35Å - 2013-10-23
A49-like RNA polymerase I associated factor (100%) (view alignment) RPA49 (Q01080) RPB8 (P20436), RPB5 (P20434), RPA43 (P46669), RPA190 (P10964), RPO26 (P20435), RPA135 (P22138), RRN11 (Q04712), RPC40 (P07703), RPA12 (P32529), RPA14 (P50106), RPB10 (P22139), RPC10 (P40422), RRN3 (P36070), RPC19 (P28000), RRN7 (P40992), RPA34 (P47006), RRN6 (P32786) BAKER'S YEAST 5N5Y_M 100 0 7.7Å - 2017-04-05
A49-like RNA polymerase I associated factor (100%) (view alignment) RPA49 (Q01080) RPC10 (P40422), RPB8 (P20436), RPB5 (P20434), RPC19 (P28000), RPA43 (P46669), RPA190 (P10964), RPA34 (P47006), RPO26 (P20435), RPA135 (P22138), RPC40 (P07703), RPA12 (P32529), RPA14 (P50106), RPB10 (P22139) BAKER'S YEAST 4C3H_M 100 0 3.27Å - 2013-10-23
A49-like RNA polymerase I associated factor (100%) (view alignment) RPA49 (Q01080) RPC10 (P40422), RPB8 (P20436), RPB5 (P20434), RPC19 (P28000), RPA43 (P46669), RPA190 (P10964), RPA34 (P47006), RPO26 (P20435), RPA135 (P22138), RPC40 (P07703), RPA12 (P32529), RPA14 (P50106), RPB10 (P22139) BAKER'S YEAST 5M3F_M 100 0 3.8Å - 2016-11-23
A49-like RNA polymerase I associated factor (62%) (view alignment) RPA49 (Q01080) - YEAST 3NFI_E 100 0 1.9Å PE4 2010-09-08