Molecular Target Synopsis
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SSL2 (Q00578) - Druggability - Molecular Target Synopsis

Chain-based assessment (last updated 08/10/2019)
Structural Druggability Help: Help

Chain-based assessment (last updated 08/10/2019)


Chains assessed5
Chains with at least one site assessed as druggable using the strict criteria5
Chains with at least one site assessed as druggable using the relaxed criteria5


		
PDB Chain Protein Name Druggable Relaxed Druggable Strict Details
6GYM_7 General transcription and DNA repair factor IIH helicase subunit XPB Yes Yes show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 2.18 73.4 34.1 Yes Yes
2 empty 2.09 63.8 28.3 No No
3 empty 1.71 75.3 24.9 No No
4 empty 2.12 71.3 21 No No
5 empty 2.26 57.6 23.5 No No
6 empty 1.91 66.8 17.3 No No
7 empty 1.97 69.7 12.8 No No
8 empty 1.92 68.6 15.6 No No
9 empty 1.69 78.5 11.5 No No
10 empty 1.79 65.9 12.4 No No
5FMF_1 General transcription and DNA repair factor IIH helicase subunit XPB Yes Yes show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 2.12 68.4 48.2 Yes Yes
2 empty 1.68 67.4 32.4 No No
3 empty 2.4 64.9 34.2 No No
4 empty 1.93 67.7 23 No No
5 empty 2 74.1 17.6 No No
6 empty 2.11 72.3 15.9 No No
7 empty 2.9 61.1 23.8 No No
8 empty 2.9 65.1 13.9 No No
9 empty 1.93 67.1 10.7 No No
10 empty 2.67 70.8 8 No No
5OQJ_7 General transcription and DNA repair factor IIH helicase subunit XPB Yes Yes show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 1.85 74.1 35.4 Yes Yes
2 empty 1.68 75.4 26.3 Yes No
3 empty 2.33 63.3 32.4 No No
4 empty 2.18 72.2 20.9 No No
5 empty 2.21 73.3 22.1 No No
6 empty 2.12 72 23.3 No No
7 empty 1.53 77.8 12.8 No No
8 empty 1.93 72 15.9 No No
9 empty 1.83 61.8 17.9 No No
10 empty 2.02 62.3 13.5 No No
5SVA_Z General transcription and DNA repair factor IIH helicase subunit XPB Yes Yes show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 2.08 68.6 51.2 Yes Yes
2 empty 1.71 68.3 31.9 No No
3 empty 2.28 59.2 34.6 No No
4 empty 2.23 68.8 17.6 No No
5 empty 2.19 70.9 14.5 No No
6 empty 2.81 57.8 23.5 No No
7 empty 2.68 67.7 11 No No
8 empty 2.32 65.5 16.4 No No
9 empty 2.31 68.5 11.9 No No
10 empty 2.82 67.6 11.6 No No
5OQM_7 General transcription and DNA repair factor IIH helicase subunit XPB Yes Yes show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 1.82 73 47.1 Yes Yes
2 empty 1.77 75.6 28.9 No No
3 empty 2.1 74.4 21.8 No No
4 empty 2.27 61.1 24 No No
5 empty 2.26 71.2 20.1 No No
6 empty 1.86 72 23.4 No No
7 empty 1.55 77.2 11.7 No No
8 empty 2.2 69.1 15.2 No No
9 empty 2.23 62.9 15.7 No No
10 empty 1.9 66 12.8 No No
Ligand-based Druggability Score:
Ligand-based Druggability Score Percentile: %
Ligand-based Druggability Help: Help




		
This protein has no network-based druggability score