CaMKII (Q00168) - Overview - Molecular Target Synopsis
CaMKII, Calcium/calmodulin-dependent protein kinase type II alpha chain
Enzyme Classification 18.104.22.168
Also Known as KCC2A_DROME, CaMKII, CaM
A key regulator of plasticity in synaptic physiology and behavior, alterations in its activity produce pleiotrophic effects that involve synaptic transmission and development as well as various aspects of behavior. Directly modulates eag potassium channels. Interacts with CASK.
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GO terms: CaMKII is active in the following subcellular-locations: axon, calcium- and calmodulin-dependent protein kinase complex, cytoplasm, dendrite, neuron projection, postsynaptic membrane, presynaptic active zone.