Molecular Target Synopsis
Overview
Domains and Structures
Drugs and Clinical Candidates
Druggability
Chemistry
Ligand Efficiency Plot
Pathways
Family Cladogram
Interaction Network
Gene Expression
Gene Copy Number Variation
RNAi
Mutations
Germline Genetics

mmpS4 (P9WJS9) - Overview - Molecular Target Synopsis

Protein


mmpS4, Siderophore export accessory protein MmpS4
UniProt P9WJS9

Also Known as MMPS4_MYCTU, mmpS4

Part of an export system, which is required for biosynthesis and secretion of siderophores. Essential for virulence. Interacts with MmpL4. Can also interact with MmpL5.

2LW3
SOLUTION STRUCTURE OF THE SOLUBLE DOMAIN OF MMPS4 FROM MYCOBACTERIUM TUBERCULOSIS
RCSB/PDB
Inspect Structure
See all 3D Structures for mmpS4

Isoforms / Transcripts (Protein Coding)


Protein Length Ensembl Gene Ensembl Transcript Ensembl Protein Uniprot Isoform

Sub-cellular localization


UniProt: mmpS4 is active in the following subcellular-locations: cell inner membrane.
GO terms: mmpS4 is active in the following subcellular-locations: integral component of membrane, plasma membrane.



UniProt
GO terms

Gene Copy Number Variation


In COSMIC - Cell Lines Project mmpS4 has gain in 0 cell-lines, loss in 0 cell-lines and no signal in 0 cell-lines. (see details)

3D Structures


For mmpS4 there are:
1 structures (1 chains) solved
0 are solved in complex with at least one small molecule ligand



(see details)
Molecular Target 3D Synopsis