Molecular Target Synopsis
Overview
Domains and Structures
Drugs and Clinical Candidates
Druggability
Chemistry
Ligand Efficiency Plot
Pathways
Family Cladogram
Interaction Network
Gene Expression
Gene Copy Number Variation
RNAi
Mutations
Germline Genetics

cbaB (P98052) - Overview - Molecular Target Synopsis

Protein


cbaB, Cytochrome c oxidase subunit 2
Enzyme Classification 1.9.3.1
UniProt P98052

Also Known as COX2_THETH, cbaB, ctaC

Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B).

2LLN
SOLUTION STRUCTURE OF THERMUS THERMOPHILUS APO-CUA
RCSB/PDB
Inspect Structure
See all 3D Structures for cbaB

Isoforms / Transcripts (Protein Coding)


Protein Length Ensembl Gene Ensembl Transcript Ensembl Protein Uniprot Isoform
135P98052-1

Sub-cellular localization


UniProt: cbaB is active in the following subcellular-locations: cell membrane.
GO terms: cbaB is active in the following subcellular-locations: integral component of membrane, plasma membrane, respirasome.



UniProt
GO terms

Gene Copy Number Variation


In COSMIC - Cell Lines Project cbaB has gain in 0 cell-lines, loss in 0 cell-lines and no signal in 0 cell-lines. (see details)

3D Structures


For cbaB there are:
3 structures (4 chains) solved
0 are solved in complex with at least one small molecule ligand



(see details)
Molecular Target 3D Synopsis