Molecular Target Synopsis
Overview
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Drugs and Clinical Candidates
Druggability
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Etv6 (P97360) - Druggability - Molecular Target Synopsis

Chain-based assessment (last updated 23/07/2019)
Structural Druggability Help: Help

Chain-based assessment (last updated 23/07/2019)


Chains assessed4
Chains with at least one site assessed as druggable using the strict criteria1
Chains with at least one site assessed as druggable using the relaxed criteria3


		
PDB Chain Protein Name Druggable Relaxed Druggable Strict Details
4MHG_A Transcription factor ETV6 No No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 2.19 59.3 18.8 No No
2 empty 1.95 64 22 No No
3 empty 2.77 60.5 17.5 No No
4 empty 2.35 66.1 15.6 No No
5 empty 2.24 66.2 12.4 No No
6 empty 2.89 61 17.5 No No
7 empty 2.13 59.4 10.8 No No
8 empty 2.64 62.6 8.6 No No
9 empty 2.39 57.2 9.1 No No
10 empty 2.85 59.8 7.5 No No
2LF7_A Transcription factor ETV6 Yes No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 2.46 59.1 29.7 Yes No
2 empty 2.42 64 14.3 No No
3 empty 2.57 64 16.8 No No
4 empty 2.1 64.6 12.1 No No
5 empty 2.54 60.6 13.7 No No
6 empty 2.65 64.4 10.6 No No
7 empty 2.79 62.6 9.6 No No
8 empty 3.08 65 9.9 No No
9 empty 3.18 70.1 7.3 No No
10 empty 1.7 54.4 10.1 No No
2MD5_A Transcription factor ETV6 Yes No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 2.44 62.6 30.5 Yes No
2 empty 2.12 68.4 18.9 No No
3 empty 2.05 70 11.5 No No
4 empty 2.61 66.8 14.8 No No
5 empty 2.55 64.1 13.6 No No
6 empty .61 98 0 Yes No
7 empty 2.67 79.3 7.4 No No
8 empty 2.36 51.9 10.8 No No
9 empty 2.85 45.8 10.6 No No
10 empty 2.2 61.2 8.5 No No
2LF8_A Transcription factor ETV6 Yes Yes show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 2.96 66.9 23 Yes Yes
2 empty 2.3 67.1 15 No No
3 empty 2.57 64.9 17.2 No No
4 empty 2.49 70 9.3 No No
5 empty 2.61 67.4 10.9 No No
6 empty 2.77 60.4 11.6 No No
7 empty 2.84 57.1 9.2 No No
8 empty 2.94 64.6 12.6 No No
9 empty 2.3 63.2 9.4 No No
10 empty 3.44 72.3 7.1 No No
Ligand-based Druggability Score:
Ligand-based Druggability Score Percentile: %
Ligand-based Druggability Help: Help




		
This protein has no network-based druggability score