Molecular Target Synopsis
Overview
Domains and Structures
Drugs and Clinical Candidates
Druggability
Chemistry
Ligand Efficiency Plot
Pathways
Family Cladogram
Interaction Network
Gene Expression
Gene Copy Number Variation
RNAi
Mutations
Germline Genetics

AGPS (P97275) - Overview - Molecular Target Synopsis

Protein


AGPS, Alkyldihydroxyacetonephosphate synthase, peroxisomal
Enzyme Classification 2.5.1.26
UniProt P97275

Also Known as ADAS_CAVPO, AGPS

Catalyzes the exchange of an acyl for a long-chain alkyl group and the formation of the ether bond in the biosynthesis of ether phospholipids. Homodimer.

6GOU
DEVELOPMENT OF ALKYL GLYCERONE PHOSPHATE SYNTHASE INHIBITORS: COMPLEX WITH INHIBITOR 2I
RCSB/PDB
Inspect Structure
See all 3D Structures for AGPS

Isoforms / Transcripts (Protein Coding)


Protein Length Ensembl Gene Ensembl Transcript Ensembl Protein Uniprot Isoform
658P97275-1

Sub-cellular localization


UniProt: AGPS is active in the following subcellular-locations: peroxisome.
GO terms: AGPS is active in the following subcellular-locations: nucleolus, peroxisome.



UniProt
GO terms

Gene Copy Number Variation


In COSMIC - Cell Lines Project AGPS has gain in 0 cell-lines, loss in 0 cell-lines and no signal in 0 cell-lines. (see details)

3D Structures


For AGPS there are:
9 structures (36 chains) solved
9 are solved in complex with at least one small molecule ligand



(see details)
Molecular Target 3D Synopsis