Trxr-1, Thioredoxin reductase 1, mitochondrial
Enzyme Classification 184.108.40.206
Also Known as
TRXR1_DROME, Trxr-1, GR
Thioredoxin system is a major player in glutathione metabolism, due to the demonstrated absence of a glutathione reductase. Functionally interacts with the Sod/Cat reactive oxidation species (ROS) defense system and thereby has a role in preadult development and life span. Lack of a glutathione reductase suggests antioxidant defense in Drosophila, and probably in related insects, differs fundamentally from that in other organisms. Homodimer.