Molecular Target Synopsis
Overview
Domains and Structures
Drugs and Clinical Candidates
Druggability
Chemistry
Ligand Efficiency Plot
Pathways
Family Cladogram
Interaction Network
Gene Expression
Gene Copy Number Variation
RNAi
Mutations
Germline Genetics

(P84776) - Overview - Molecular Target Synopsis

Protein


, Basic phospholipase A2 homolog zhaoermiatoxin
UniProt P84776

Also Known as PA2H_PROMB

Snake venom phospholipase A2 homolog that induces myonecrosis, and edema. Has low myotoxic activity. Homodimer.

2PH4
CRYSTAL STRUCTURE OF A NOVEL ARG49 PHOSPHOLIPASE A2 HOMOLOGUE FROM ZHAOERMIA MANGSHANENSIS VENOM
RCSB/PDB
Inspect Structure
See all 3D Structures for

Isoforms / Transcripts (Protein Coding)


Protein Length Ensembl Gene Ensembl Transcript Ensembl Protein Uniprot Isoform
121P84776-1

Sub-cellular localization


UniProt: is active in the following subcellular-locations: secreted.
GO terms: is active in the following subcellular-locations: extracellular region.



UniProt
GO terms

Gene Copy Number Variation


In COSMIC - Cell Lines Project has gain in 0 cell-lines, loss in 0 cell-lines and no signal in 0 cell-lines. (see details)

3D Structures


For there are:
1 structures (2 chains) solved
0 are solved in complex with at least one small molecule ligand



(see details)
Molecular Target 3D Synopsis

Screening and Chemistry


has been screened with compounds ( bioactivities). (see details)