Molecular Target Synopsis
Overview
Domains and Structures
Drugs and Clinical Candidates
Druggability
Chemistry
Ligand Efficiency Plot
Pathways
Family Cladogram
Interaction Network
Gene Expression
Gene Copy Number Variation
RNAi
Mutations
Germline Genetics

gst (P81065) - Overview - Molecular Target Synopsis

Protein


gst, Glutathione S-transferase
Enzyme Classification 2.5.1.18
UniProt P81065

Also Known as GST_OCHAN, gst

Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles. Homodimer.

2PVQ
CRYSTAL STRUCTURE OF OCHROBACTRUM ANTHROPI GLUTATHIONE TRANSFERASE CYS10ALA MUTANT WITH GLUTATHIONE BOUND AT THE H-SITE
RCSB/PDB
Inspect Structure
See all 3D Structures for gst

Isoforms / Transcripts (Protein Coding)


Protein Length Ensembl Gene Ensembl Transcript Ensembl Protein Uniprot Isoform
201P81065-1

Sub-cellular localization


UniProt: gst is active in the following subcellular-locations: cytoplasm.
GO terms: gst is active in the following subcellular-locations: cytoplasm.



UniProt
GO terms

Gene Copy Number Variation


In COSMIC - Cell Lines Project gst has gain in 0 cell-lines, loss in 0 cell-lines and no signal in 0 cell-lines. (see details)

3D Structures


For gst there are:
2 structures (2 chains) solved
2 are solved in complex with at least one small molecule ligand



(see details)
Molecular Target 3D Synopsis