Molecular Target Synopsis
Overview
Domains and Structures
Drugs and Clinical Candidates
Druggability
Chemistry
Ligand Efficiency Plot
Pathways
Family Cladogram
Interaction Network
Gene Expression
Gene Copy Number Variation
RNAi
Mutations
Germline Genetics

rpsB (P80371) - Overview - Molecular Target Synopsis

Protein


rpsB, 30S ribosomal protein S2
UniProt P80371

Also Known as RS2_THET8, rpsB, rps2

Spans the head-body hinge region of the 30S subunit. Is loosely associated with the 30S subunit. Part of the 30S ribosomal subunit. Contacts protein S8 and may contact the N-terminus of Era.

6MPF
STRUCTURE OF THE THERMUS THERMOPHILUS 30S RIBOSOMAL SUBUNIT COMPLEXED WITH A 2-THIOCYTIDINE (S2C32) AND INOSINE (I34) MODIFIED ANTICODON STEM LOOP (ASL) OF ESCHERICHIA COLI TRANSFER RNA ARGININE 1 (TRNAARG1) BOUND TO AN MRNA WITH AN CGC-CODON IN THE A-SITE AND PAROMOMYCIN
RCSB/PDB
Inspect Structure
See all 3D Structures for rpsB

Isoforms / Transcripts (Protein Coding)


Protein Length Ensembl Gene Ensembl Transcript Ensembl Protein Uniprot Isoform
256P80371-1, P62662-1

Sub-cellular localization


GO terms: rpsB is active in the following subcellular-locations: small ribosomal subunit.



UniProt
GO terms

Gene Copy Number Variation


In COSMIC - Cell Lines Project rpsB has gain in 0 cell-lines, loss in 0 cell-lines and no signal in 0 cell-lines. (see details)

3D Structures


For rpsB there are:
125 structures (125 chains) solved
4 are solved in complex with at least one small molecule ligand



(see details)
Molecular Target 3D Synopsis

Screening and Chemistry


rpsB has been screened with compounds ( bioactivities). (see details)