Molecular Target Synopsis
Overview
Domains and Structures
Drugs and Clinical Candidates
Druggability
Chemistry
Ligand Efficiency Plot
Pathways
Family Cladogram
Interaction Network
Gene Expression
Gene Copy Number Variation
RNAi
Mutations
Germline Genetics

trpS (P75510) - Overview - Molecular Target Synopsis

Protein


trpS, Tryptophan--tRNA ligase
Enzyme Classification 6.1.1.2
UniProt P75510

Also Known as SYW_MYCPN, trpS

Catalyzes the attachment of tryptophan to tRNA(Trp). Homodimer.

2YY5
CRYSTAL STRUCTURE OF TRYPTOPHANYL-TRNA SYNTHETASE FROM MYCOPLASMA PNEUMONIAE
RCSB/PDB
Inspect Structure
See all 3D Structures for trpS

Isoforms / Transcripts (Protein Coding)


Protein Length Ensembl Gene Ensembl Transcript Ensembl Protein Uniprot Isoform
346P75510-1

Sub-cellular localization


UniProt: trpS is active in the following subcellular-locations: cytoplasm.
GO terms: trpS is active in the following subcellular-locations: cytoplasm.



UniProt
GO terms

Gene Copy Number Variation


In COSMIC - Cell Lines Project trpS has gain in 0 cell-lines, loss in 0 cell-lines and no signal in 0 cell-lines. (see details)

3D Structures


For trpS there are:
1 structures (4 chains) solved
1 are solved in complex with at least one small molecule ligand



(see details)
Molecular Target 3D Synopsis

Screening and Chemistry


trpS has been screened with compounds ( bioactivities). (see details)