Molecular Target Synopsis
Overview
Domains and Structures
Drugs and Clinical Candidates
Druggability
Chemistry
Ligand Efficiency Plot
Pathways
Family Cladogram
Interaction Network
Gene Expression
Gene Copy Number Variation
RNAi
Mutations
Germline Genetics

pacS (P73241) - Overview - Molecular Target Synopsis

Protein


pacS, Probable copper-transporting ATPase PacS
Enzyme Classification 7.2.2.8
UniProt P73241

Also Known as ATCS_SYNY3, pacS

May play a role in the osmotic adaptation.

4A48
CROSSTALK BETWEEN CU(I) AND ZN(II) HOMEOSTASIS
RCSB/PDB
Inspect Structure
See all 3D Structures for pacS

Isoforms / Transcripts (Protein Coding)


Protein Length Ensembl Gene Ensembl Transcript Ensembl Protein Uniprot Isoform
745P73241-1

Sub-cellular localization


UniProt: pacS is active in the following subcellular-locations: cell membrane.
GO terms: pacS is active in the following subcellular-locations: integral component of membrane, plasma membrane.



UniProt
GO terms

Gene Copy Number Variation


In COSMIC - Cell Lines Project pacS has gain in 0 cell-lines, loss in 0 cell-lines and no signal in 0 cell-lines. (see details)

3D Structures


For pacS there are:
4 structures (5 chains) solved
0 are solved in complex with at least one small molecule ligand



(see details)
Molecular Target 3D Synopsis

Screening and Chemistry


pacS has been screened with compounds ( bioactivities). (see details)