Molecular Target Synopsis
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rpsT (P62661) - Druggability - Molecular Target Synopsis

Chain-based assessment (last updated 10/09/2019)
Domain-based assessment (last updated 30/07/2012)


Structural Druggability Help: Help

Chain-based assessment (last updated 10/09/2019)


Chains assessed5
Chains with at least one site assessed as druggable using the strict criteria0
Chains with at least one site assessed as druggable using the relaxed criteria2


		
PDB Chain Protein Name Druggable Relaxed Druggable Strict Details
4KVB_T 30S ribosomal protein S20 No No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 2.19 68.7 12 No No
2 empty 2.33 64.6 18.8 No No
3 empty 2.39 57.9 16.8 No No
4 empty 2.46 66.6 14.5 No No
5 empty 2.31 55.9 16.4 No No
6 empty 2.62 67.6 8.7 No No
7 empty 2.7 56.7 8.5 No No
8 empty 3.11 44.9 8.8 No No
9 empty 3.27 74.3 6.2 No No
10 empty 2.18 65.6 6.3 No No
3T1Y_T 30S ribosomal protein S20 No No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 2.26 69.7 20.5 No No
2 empty 2.56 69.7 10.7 No No
3 empty 2.6 55.3 15.1 No No
4 empty 2.58 55.7 13.9 No No
5 empty 2.45 69.6 10.4 No No
6 empty 1.77 67.3 9.6 No No
7 empty 2.35 59.3 10.3 No No
8 empty 2.84 53.4 11 No No
9 empty 3.22 60.6 8.5 No No
10 empty 2.91 53.5 8.5 No No
2VQE_T 30S ribosomal protein S20 Yes No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 2.23 71.4 13.3 Yes No
2 empty 2.64 66.1 11 No No
3 empty 2.46 56.7 19.1 No No
4 empty 2.13 55.8 12.7 No No
5 empty 2.81 57.4 11.1 No No
6 empty 2.58 67.1 7.7 No No
7 empty 1.77 59.5 10.1 No No
8 empty 1.85 75.5 6.6 No No
9 empty 3.35 67.3 6.1 No No
10 empty 2.63 83.3 0 No No
2VQF_T 30S ribosomal protein S20 No No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 2.13 69.9 13.8 No No
2 empty 2.34 58.1 13.1 No No
3 empty 2.54 67 11.5 No No
4 empty 2.53 59.5 14.1 No No
5 empty 2.84 61.2 11.8 No No
6 empty 1.8 81.2 7 No No
7 empty 2.56 77 0 No No
8 empty 2.29 51.1 7.8 No No
9 empty 3.55 69.1 5.7 No No
10 empty 1.66 50 7.1 No No
3T1H_T 30S ribosomal protein S20 Yes No show/hide
Site num Site Status Pickpocket Polar Ratio Surfnet Gap Vertices Buried Surfnet Long Axis Druggable Relaxed Druggable Strict
1 empty 2.03 72.6 13.2 Yes No
2 empty 2.55 64 11.3 No No
3 empty 2.34 58.1 14.1 No No
4 empty 2.24 56.6 12.4 No No
5 empty 2.21 63.2 8.5 No No
6 empty 2.75 55.1 12.3 No No
7 empty 1.76 62.3 9.4 No No
8 empty 2.54 64.7 10.1 No No
9 empty 2.59 72.7 8.5 No No
10 empty 2.36 63 6.4 No No

Domain-based assessment (last updated 30/07/2012)


Domains assessed14
Domains assessed as druggable using the strict criteria2
Domains assessed as druggable using the relaxed criteria3

PDB (Domain) Protein Name Domain Resolution Ligands Druggable Relaxed Druggable Strict
1VOX_T (113852) 30S ribosomal protein S20 Ribosome and ribosomal fragments, Ribosome and ribosomal fragments, Ribosome complexes 11.5Å Yes Yes
2QNH_U (4151167) 30S ribosomal protein S20 UNMATCHED, UNMATCHED, UNMATCHED 2QNH 3.83Å Yes Yes
2VQE_T (153444) 30S ribosomal protein S20 Spectrin repeat-like, Ribosomal protein S20, Ribosomal protein S20 2.5Å Yes No
2VQF_T (153463) 30S ribosomal protein S20 Spectrin repeat-like, Ribosomal protein S20, Ribosomal protein S20 2.9Å No No
3D5A_T (157353) 30S ribosomal protein S20 Spectrin repeat-like, Ribosomal protein S20, Ribosomal protein S20 3.2Å No No
3D5C_T (157383) 30S ribosomal protein S20 Spectrin repeat-like, Ribosomal protein S20, Ribosomal protein S20 3.2Å No No
3F1E_T (3390923) 30S ribosomal protein S20 Spectrin repeat-like, Ribosomal protein S20, UNMATCHED 3Å No No
3F1G_T (3390986) 30S ribosomal protein S20 Spectrin repeat-like, Ribosomal protein S20, UNMATCHED 3Å No No
3MR8_T (3550738) 30S ribosomal protein S20 Spectrin repeat-like, Ribosomal protein S20, UNMATCHED 3.514Å No No
3MS0_T (3550802) 30S ribosomal protein S20 Spectrin repeat-like, Ribosomal protein S20, UNMATCHED 3.52Å No No
3PYN_T (3680154) 30S ribosomal protein S20 Spectrin repeat-like, Ribosomal protein S20, UNMATCHED 3.5Å No No
3PYQ_T (3680209) 30S ribosomal protein S20 Spectrin repeat-like, Ribosomal protein S20, UNMATCHED 3.5Å No No
3PYS_T (3680264) 30S ribosomal protein S20 Spectrin repeat-like, Ribosomal protein S20, UNMATCHED 3.4Å No No
3PYU_T (3680319) 30S ribosomal protein S20 Spectrin repeat-like, Ribosomal protein S20, UNMATCHED 3.4Å No No
Ligand-based Druggability Score:
Ligand-based Druggability Score Percentile: %
Ligand-based Druggability Help: Help




		
This protein has no network-based druggability score