Molecular Target Synopsis
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PKIA (P61925) - Domains And Structures - Molecular Target Synopsis

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Structural Sequence Similarity Matches
Domains Covered Gene Name (Uniprot) Solved in Complex with Organism PDB Chain Identity E-Value Resolution Ligands Release Date
cAMP-dependent protein kinase inhibitor (29%) (view alignment) PKIA (P61925) PRKACA (P00517) HUMAN 2UW5_I 100 0 2.14Å - 2007-05-08
cAMP-dependent protein kinase inhibitor (29%) (view alignment) PKIA (P61925) PRKACA (P17612) HUMAN 4UJ1_B 100 0 1.77Å - 2016-04-13
cAMP-dependent protein kinase inhibitor (29%) (view alignment) PKIA (P61925) PRKACA (P17612) HUMAN 3OVV_B 100 0 1.58Å - 2011-09-21
cAMP-dependent protein kinase inhibitor (29%) (view alignment) PKIA (P61925) PRKACA (P00517) HUMAN 4IJ9_I 100 0 1.99Å - 2013-05-01
cAMP-dependent protein kinase inhibitor (29%) (view alignment) PKIA (P61925) Prkaca (P05132) HUMAN 4IAD_S 100 0 1.9Å - 2013-06-12
cAMP-dependent protein kinase inhibitor (29%) (view alignment) PKIA (P61925) PRKACA (P00517) HUMAN 2UVX_I 100 0 2Å - 2007-05-08
cAMP-dependent protein kinase inhibitor (29%) (view alignment) PKIA (P61925) PRKACA (P17612) 3OXT_B 100 0 2.2Å - 2011-09-28
cAMP-dependent protein kinase inhibitor (29%) (view alignment) PKIA (P61925) PRKACA (P00517) HUMAN 2JDS_I 100 0 2Å - 2007-02-13
cAMP-dependent protein kinase inhibitor (29%) (view alignment) PKIA (P61925) PRKACA (P17612) 3P0M_B 100 0 2.03Å - 2011-09-28
cAMP-dependent protein kinase inhibitor (29%) (view alignment) PKIA (P61925) PRKACA (P17612) HUMAN 4UJ2_B 100 0 2.02Å - 2016-04-13
cAMP-dependent protein kinase inhibitor (100%) (view alignment) PKIA (P61925) CRM1 (P30822), GSP1 (P32835) HUMAN 3WYG_D 100 0 2.15Å - 2014-11-12
cAMP-dependent protein kinase inhibitor (29%) (view alignment) PKIA (P61925) PRKACA (P00517) 1VEB_B 100 0 2.89Å - 2005-03-29
cAMP-dependent protein kinase inhibitor (29%) (view alignment) PKIA (P61925) PRKACA (P00517) HUMAN 2VO6_I 100 0 1.97Å - 2008-04-08
cAMP-dependent protein kinase inhibitor (27%) (view alignment) PKIA (P61925) PRKACA (P00517) HUMAN 6E99_B 100 0 1.88Å - 2018-11-14
cAMP-dependent protein kinase inhibitor (29%) (view alignment) PKIA (P61925) Prkaca (P05132) 6E21_B 100 0 2Å - 2019-04-03
cAMP-dependent protein kinase inhibitor (29%) (view alignment) PKIA (P61925) DNAJB1 (P25685), PRKACA (P17612) HUMAN 4WB7_I 100 0 1.9Å - 2015-01-21
cAMP-dependent protein kinase inhibitor (29%) (view alignment) PKIA (P61925) Prkaca (P05132) HUMAN 4IB3_S 100 0 2.2Å - 2013-12-11
cAMP-dependent protein kinase inhibitor (29%) (view alignment) PKIA (P61925) PRKACA (P17612) HUMAN 3L9L_D 100 0 1.9Å - 2011-01-19
cAMP-dependent protein kinase inhibitor (29%) (view alignment) PKIA (P61925) PRKACA (P25321) HUMAN 5LCR_B 100 0 1.56Å - 2018-01-17
cAMP-dependent protein kinase inhibitor (29%) (view alignment) PKIA (P61925) Prkaca (P05132) HUMAN 4IAZ_S 100 0 1.85Å - 2013-06-12
cAMP-dependent protein kinase inhibitor (29%) (view alignment) PKIA (P61925) PRKACA (P00517) 2C1A_I 100 0 1.95Å - 2005-11-02
cAMP-dependent protein kinase inhibitor (29%) (view alignment) PKIA (P61925) PRKACA (P25321) HUMAN 5M0B_B 100 0 1.506Å - 2018-06-06
cAMP-dependent protein kinase inhibitor (29%) (view alignment) PKIA (P61925) Prkaca (P05132) HUMAN 4IAF_S 100 0 2.2Å - 2013-06-12
cAMP-dependent protein kinase inhibitor (29%) (view alignment) PKIA (P61925) PRKACA (P17612) HUMAN 5N23_B 100 0 2.088Å - 2018-03-14
cAMP-dependent protein kinase inhibitor (29%) (view alignment) PKIA (P61925) PRKACA (P17612) HUMAN 4WB8_I 100 0 1.55Å - 2015-01-21
cAMP-dependent protein kinase inhibitor (29%) (view alignment) PKIA (P61925) Prkaca (P05132) HUMAN 4IAI_S 100 0 1.55Å - 2013-06-12
cAMP-dependent protein kinase inhibitor (29%) (view alignment) PKIA (P61925) PRKACA (P00517) HUMAN 2VNY_I 100 0 1.96Å - 2008-04-08
cAMP-dependent protein kinase inhibitor (29%) (view alignment) PKIA (P61925) PRKACA (P00517) HUMAN 2VO7_I 100 0 1.98Å - 2008-04-08
cAMP-dependent protein kinase inhibitor (29%) (view alignment) PKIA (P61925) PRKACA (P17612) HUMAN 3L9M_D 100 0 1.9Å - 2011-01-19
cAMP-dependent protein kinase inhibitor (32%) (view alignment) PKIA (P61925) PRKACA (P36887) HUMAN 1CMK_I 100 0 2.9Å - 1994-05-31
cAMP-dependent protein kinase inhibitor (29%) (view alignment) PKIA (P61925) PRKACA (P25321) HUMAN 5LCQ_B 100 0 1.42Å - 2018-01-17
cAMP-dependent protein kinase inhibitor (27%) (view alignment) PKIA (P61925) YRB1 (P41920), CRM1 (P30822), RAN (P62826) 5DH9_D 100 0 2.55Å - 2015-09-16
cAMP-dependent protein kinase inhibitor (29%) (view alignment) PKIA (P61925) Prkaca (P05132) HUMAN 4IAY_S 100 0 2Å - 2013-06-12
cAMP-dependent protein kinase inhibitor (29%) (view alignment) PKIA (P61925) PRKACA (P00517) HUMAN 2UVZ_I 100 0 1.94Å - 2007-05-08
cAMP-dependent protein kinase inhibitor (29%) (view alignment) PKIA (P61925) PRKACA (P00517) HUMAN 2UW3_I 100 0 2.19Å - 2007-05-08
cAMP-dependent protein kinase inhibitor (29%) (view alignment) PKIA (P61925) PRKACA (P25321) HUMAN 5M71_B 100 0 1.488Å - 2018-06-06
cAMP-dependent protein kinase inhibitor (29%) (view alignment) PKIA (P61925) PRKACA (P00517) HUMAN 2VO3_I 100 0 1.98Å - 2008-04-08
cAMP-dependent protein kinase inhibitor (29%) (view alignment) PKIA (P61925) PRKACA (P17612) 3POO_B 100 0 1.6Å - 2011-11-16
cAMP-dependent protein kinase inhibitor (29%) (view alignment) PKIA (P61925) PRKACA (P17612) HUMAN 3L9M_C 100 0 1.9Å - 2011-01-19
cAMP-dependent protein kinase inhibitor (29%) (view alignment) PKIA (P61925) PRKACA (P00517) 1XH6_B 100 0 1.9Å - 2005-09-17
cAMP-dependent protein kinase inhibitor (29%) (view alignment) PKIA (P61925) PRKACA (P17612) 3MVJ_J 100 0 2.49Å - 2010-06-02
cAMP-dependent protein kinase inhibitor (29%) (view alignment) PKIA (P61925) PRKACA (P25321) HUMAN 5LCT_B 100 0 1.615Å - 2018-01-17
cAMP-dependent protein kinase inhibitor (29%) (view alignment) PKIA (P61925) PRKACA (P00517) 1Q61_I 100 0 2.1Å - 2003-09-30
cAMP-dependent protein kinase inhibitor (29%) (view alignment) PKIA (P61925) PRKACA (P00517) HUMAN 4IE9_I 100 0 1.92Å - 2013-05-01
cAMP-dependent protein kinase inhibitor (29%) (view alignment) PKIA (P61925) PRKACA (P17612) HUMAN 3OWP_B 100 0 1.88Å - 2011-09-21
cAMP-dependent protein kinase inhibitor (29%) (view alignment) PKIA (P61925) PRKACA (P17612) HUMAN 5BX6_B 100 0 1.89Å - 2016-09-14
cAMP-dependent protein kinase inhibitor (29%) (view alignment) PKIA (P61925) PRKACA (P00517) HUMAN 2UW4_I 100 0 2Å - 2007-05-08
cAMP-dependent protein kinase inhibitor (29%) (view alignment) PKIA (P61925) Prkaca (P05132) HUMAN 4IB0_S 100 0 1.87Å - 2013-12-11
cAMP-dependent protein kinase inhibitor (29%) (view alignment) PKIA (P61925) PRKACA (P00517) HUMAN 2VO0_I 100 0 1.94Å - 2008-04-08
cAMP-dependent protein kinase inhibitor (29%) (view alignment) PKIA (P61925) Prkaca (P05132) HUMAN 4O22_S 100 0 1.7Å - 2014-05-28
cAMP-dependent protein kinase inhibitor (29%) (view alignment) PKIA (P61925) PRKACA (P17612) HUMAN 4WB5_I 100 0 1.64Å - 2015-01-21
cAMP-dependent protein kinase inhibitor (29%) (view alignment) PKIA (P61925) PRKACA (P17612) HUMAN 3VQH_B 100 0 1.73Å - 2012-08-15
cAMP-dependent protein kinase inhibitor (29%) (view alignment) PKIA (P61925) PRKACA (P17612) 3MVJ_K 100 0 2.49Å - 2010-06-02
cAMP-dependent protein kinase inhibitor (29%) (view alignment) PKIA (P61925) PRKACA (P17612) HUMAN 6FRX_B 100 0 1.88Å - 2019-03-13
cAMP-dependent protein kinase inhibitor (29%) (view alignment) PKIA (P61925) PRKACA (P00517) HUMAN 2UW6_I 100 0 2.23Å - 2007-05-08
cAMP-dependent protein kinase inhibitor (29%) (view alignment) PKIA (P61925) PRKACA (P25321) HUMAN 5M0U_B 100 0 1.667Å - 2018-06-06
cAMP-dependent protein kinase inhibitor (29%) (view alignment) PKIA (P61925) PRKACA (P25321) HUMAN 5M75_B 100 0 1.538Å - 2018-06-06
cAMP-dependent protein kinase inhibitor (29%) (view alignment) PKIA (P61925) PRKACA (P00517) HUMAN 2UW8_I 100 0 2Å - 2007-05-08
cAMP-dependent protein kinase inhibitor (29%) (view alignment) PKIA (P61925) PRKACA (P00517) HUMAN 4AXA_I 100 0 1.9Å - 2012-07-25
cAMP-dependent protein kinase inhibitor (29%) (view alignment) PKIA (P61925) PRKACA (P00517) 2C1B_I 100 0 2Å - 2005-11-02
cAMP-dependent protein kinase inhibitor (29%) (view alignment) PKIA (P61925) PRKACA (P17612) HUMAN 4WB6_J 100 0 2.1Å - 2015-01-21
cAMP-dependent protein kinase inhibitor (29%) (view alignment) PKIA (P61925) PRKACA (P25321) HUMAN 5M0C_B 100 0 1.73Å - 2018-06-06
cAMP-dependent protein kinase inhibitor (37%) (view alignment) PKIA (P61925) XPO1 (O14980) HUMAN 2L1L_A 100 0 - 2011-06-15
cAMP-dependent protein kinase inhibitor (29%) (view alignment) PKIA (P61925) PRKACA (P00517) HUMAN 2UW0_I 100 0 2Å - 2007-05-08
cAMP-dependent protein kinase inhibitor (29%) (view alignment) PKIA (P61925) PRKACA (P00517) HUMAN 2VNW_I 100 0 2.09Å - 2008-04-08
cAMP-dependent protein kinase inhibitor (29%) (view alignment) PKIA (P61925) Prkaca (P05132) HUMAN 4O21_S 100 0 1.95Å 2RX 2014-05-28
cAMP-dependent protein kinase inhibitor (29%) (view alignment) PKIA (P61925) PRKACA (P00517) 1XH8_B 100 0 1.6Å - 2005-09-17
cAMP-dependent protein kinase inhibitor (29%) (view alignment) PKIA (P61925) Prkaca (P05132) 3X2W_S 100 0 1.7Å - 2015-12-16
cAMP-dependent protein kinase inhibitor (29%) (view alignment) PKIA (P61925) PRKACA (P17612) HUMAN 3L9L_C 100 0 1.9Å - 2011-01-19
cAMP-dependent protein kinase inhibitor (29%) (view alignment) PKIA (P61925) PRKACA (P17612) HUMAN 4UJB_B 100 0 1.95Å - 2016-04-13
cAMP-dependent protein kinase inhibitor (29%) (view alignment) PKIA (P61925) PRKACA (P17612) 3NX8_B 100 0 2Å - 2011-07-13
cAMP-dependent protein kinase inhibitor (29%) (view alignment) PKIA (P61925) PRKACA (P17612) HUMAN 3L9N_C 100 0 2Å - 2011-01-19
cAMP-dependent protein kinase inhibitor (29%) (view alignment) PKIA (P61925) PRKACA (P17612) HUMAN 4UJ9_B 100 0 1.87Å - 2016-04-13
cAMP-dependent protein kinase inhibitor (29%) (view alignment) PKIA (P61925) PRKACA (P00517) 1YDR_I 100 0 2.2Å - 1997-04-01
cAMP-dependent protein kinase inhibitor (29%) (view alignment) PKIA (P61925) PRKACA (P17612) 3OOG_B 100 0 2Å - 2011-08-31
cAMP-dependent protein kinase inhibitor (29%) (view alignment) PKIA (P61925) PRKACA (P00517) 1XH9_B 100 0 1.64Å - 2005-09-17
cAMP-dependent protein kinase inhibitor (29%) (view alignment) PKIA (P61925) Prkaca (P05132) HUMAN 4IAK_S 100 0 1.6Å - 2013-06-12
cAMP-dependent protein kinase inhibitor (29%) (view alignment) PKIA (P61925) DNAJB1 (P25685), PRKACA (P17612) HUMAN 4WB7_J 100 0 1.9Å - 2015-01-21
cAMP-dependent protein kinase inhibitor (29%) (view alignment) PKIA (P61925) PRKACA (P25321) HUMAN 5LCU_B 100 0 1.579Å - 2018-01-17
cAMP-dependent protein kinase inhibitor (29%) (view alignment) PKIA (P61925) PRKACA (P25321) HUMAN 5LCP_B 100 0 1.43Å - 2018-01-17
cAMP-dependent protein kinase inhibitor (29%) (view alignment) PKIA (P61925) PRKACA (P00517) 2F7E_I 100 0 2Å - 2006-06-27
cAMP-dependent protein kinase inhibitor (27%) (view alignment) PKIA (P61925) PRKACA (P00517) HUMAN 6E9L_B 100 0 2.7Å - 2018-11-14
cAMP-dependent protein kinase inhibitor (29%) (view alignment) PKIA (P61925) Prkaca (P05132) 1JLU_S 100 0 2.25Å - 2001-08-01
cAMP-dependent protein kinase inhibitor (29%) (view alignment) PKIA (P61925) PRKACA (P00517) HUMAN 2JDV_I 100 0 2.08Å - 2007-02-13
cAMP-dependent protein kinase inhibitor (100%) (view alignment) PKIA (P61925) CRM1 (P30822) HUMAN 5XOJ_D 100 0 2.2Å - 2017-08-16
cAMP-dependent protein kinase inhibitor (29%) (view alignment) PKIA (P61925) PRKACA (P25321) HUMAN 5M0L_B 100 0 1.465Å - 2018-06-06
cAMP-dependent protein kinase inhibitor (29%) (view alignment) PKIA (P61925) PRKACA (P00517) HUMAN 2UW7_I 100 0 2.1Å - 2007-05-08
cAMP-dependent protein kinase inhibitor (29%) (view alignment) PKIA (P61925) PRKACA (P25321) HUMAN 5M6V_B 100 0 1.418Å - 2018-06-06
cAMP-dependent protein kinase inhibitor (29%) (view alignment) PKIA (P61925) PRKACA (P00517) 1XH7_B 100 0 2.47Å - 2005-09-17
cAMP-dependent protein kinase inhibitor (29%) (view alignment) PKIA (P61925) Prkaca (P05132) HUMAN 4IB1_S 100 0 1.63Å - 2013-12-11
cAMP-dependent protein kinase inhibitor (29%) (view alignment) PKIA (P61925) PRKACA (P17612) HUMAN 4WB6_I 100 0 2.1Å - 2015-01-21
cAMP-dependent protein kinase inhibitor (29%) (view alignment) PKIA (P61925) PRKACA (P00517) 1XH4_B 100 0 2.45Å - 2005-09-17
cAMP-dependent protein kinase inhibitor (29%) (view alignment) PKIA (P61925) PRKACA (P17612) HUMAN 5BX7_B 100 0 1.89Å - 2016-09-14
cAMP-dependent protein kinase inhibitor (29%) (view alignment) PKIA (P61925) PRKACA (P17612) HUMAN 3AMA_B 100 0 1.75Å - 2011-08-03
cAMP-dependent protein kinase inhibitor (29%) (view alignment) PKIA (P61925) PRKACA (P00517) 1XHA_B 100 0 2.46Å - 2005-09-17
cAMP-dependent protein kinase inhibitor (29%) (view alignment) PKIA (P61925) PRKACA (P00517) 1Q8T_B 100 0 2Å - 2003-12-16
cAMP-dependent protein kinase inhibitor (29%) (view alignment) PKIA (P61925) PRKACA (P17612) 3MVJ_I 100 0 2.49Å - 2010-06-02
cAMP-dependent protein kinase inhibitor (29%) (view alignment) PKIA (P61925) PRKACA (P00517) HUMAN 2JDT_I 100 0 2.15Å - 2007-02-13
cAMP-dependent protein kinase inhibitor (29%) (view alignment) PKIA (P61925) Prkaca (P05132) HUMAN 4IAC_S 100 0 2.15Å - 2013-06-12
cAMP-dependent protein kinase inhibitor (29%) (view alignment) PKIA (P61925) PRKACA (P00517) HUMAN 4Z84_I 100 0 1.55Å - 2015-12-02
cAMP-dependent protein kinase inhibitor (29%) (view alignment) PKIA (P61925) Prkaca (P05132) 3X2V_S 100 0 1.77Å - 2015-12-16
cAMP-dependent protein kinase inhibitor (29%) (view alignment) PKIA (P61925) PRKACA (P00517) HUMAN 4Z83_I 100 0 1.8Å - 2015-12-02
cAMP-dependent protein kinase inhibitor (29%) (view alignment) PKIA (P61925) PRKACA (P00517) 1Q62_I 100 0 2.3Å - 2003-09-30
cAMP-dependent protein kinase inhibitor (29%) (view alignment) PKIA (P61925) PRKACA (P00517) 1XH5_B 100 0 2.05Å - 2005-09-17
cAMP-dependent protein kinase inhibitor (29%) (view alignment) PKIA (P61925) PRKACA (P00517) 2GNI_I 100 0 2.27Å - 2006-05-23
cAMP-dependent protein kinase inhibitor (29%) (view alignment) PKIA (P61925) PRKACA (P00517) HUMAN 2UVY_I 100 0 1.95Å - 2007-05-08
cAMP-dependent protein kinase inhibitor (29%) (view alignment) PKIA (P61925) PRKACA (P25321) HUMAN 5M6Y_B 100 0 1.367Å - 2018-06-06
cAMP-dependent protein kinase inhibitor (29%) (view alignment) PKIA (P61925) PRKACA (P17612) HUMAN 4UJA_B 100 0 1.93Å - 2016-04-13
cAMP-dependent protein kinase inhibitor (29%) (view alignment) PKIA (P61925) Prkaca (P05132) 3X2U_S 100 0 2.4Å - 2015-12-16
cAMP-dependent protein kinase inhibitor (29%) (view alignment) PKIA (P61925) PRKACA (P17612) HUMAN 3AMB_B 100 0 2.25Å - 2011-08-03