Molecular Target Synopsis
Overview
Domains and Structures
Drugs and Clinical Candidates
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Chemistry
Ligand Efficiency Plot
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pol (P61875) - Overview - Molecular Target Synopsis

Protein


pol, DNA polymerase
Enzyme Classification 2.7.7.7
UniProt P61875

Also Known as DPOL_PYRFU, pol

In addition to polymerase activity, this DNA polymerase exhibits 3' to 5' exonuclease activity. Monomer.

4AHC
CRYSTAL STRUCTURE OF AN EVOLVED REPLICATING DNA POLYMERASE
RCSB/PDB
Inspect Structure
See all 3D Structures for pol

Isoforms / Transcripts (Protein Coding)


Protein Length Ensembl Gene Ensembl Transcript Ensembl Protein Uniprot Isoform
775P61875-1, P61876-1

Gene Copy Number Variation


In COSMIC - Cell Lines Project pol has gain in 0 cell-lines, loss in 0 cell-lines and no signal in 0 cell-lines. (see details)

3D Structures


For pol there are:
4 structures (5 chains) solved
0 are solved in complex with at least one small molecule ligand



(see details)
Molecular Target 3D Synopsis