Molecular Target Synopsis
Overview
Domains and Structures
Drugs and Clinical Candidates
Druggability
Chemistry
Ligand Efficiency Plot
Pathways
Family Cladogram
Interaction Network
Gene Expression
Gene Copy Number Variation
RNAi
Mutations
Germline Genetics

rpl10e (P60617) - Overview - Molecular Target Synopsis

Protein


rpl10e, 50S ribosomal protein L10e
UniProt P60617

Also Known as RL10E_HALMA, rpl10e

This is 1 of 5 proteins that mediate the attachment of the 5S rRNA onto the large ribosomal subunit, stabilizing the orientation of adjacent RNA domains. Modeling places the A and P site tRNAs in close proximity to this protein. Part of the 50S ribosomal subunit. Weakly binds 5S rRNA. Probably binds the A and P site tRNAs.

4ADX
THE CRYO-EM STRUCTURE OF THE ARCHAEAL 50S RIBOSOMAL SUBUNIT IN COMPLEX WITH INITIATION FACTOR 6
RCSB/PDB
Inspect Structure
See all 3D Structures for rpl10e

Isoforms / Transcripts (Protein Coding)


Protein Length Ensembl Gene Ensembl Transcript Ensembl Protein Uniprot Isoform
177P60617-1

Sub-cellular localization


GO terms: rpl10e is active in the following subcellular-locations: ribosome.



UniProt
GO terms

Gene Copy Number Variation


In COSMIC - Cell Lines Project rpl10e has gain in 0 cell-lines, loss in 0 cell-lines and no signal in 0 cell-lines. (see details)

3D Structures


For rpl10e there are:
66 structures (66 chains) solved
0 are solved in complex with at least one small molecule ligand



(see details)
Molecular Target 3D Synopsis