Molecular Target Synopsis
Overview
Domains and Structures
Drugs and Clinical Candidates
Druggability
Chemistry
Ligand Efficiency Plot
Pathways
Family Cladogram
Interaction Network
Gene Expression
Gene Copy Number Variation
RNAi
Mutations
Germline Genetics

RAB38 (P57729) - Domains And Structures - Molecular Target Synopsis

Click Here to View Molecular Target 3D Synopsis

Select a homology cutoff:
Structural Sequence Similarity Matches
Domains Covered Gene Name (Uniprot) Solved in Complex with Organism PDB Chain Identity E-Value Resolution Ligands Release Date
(view alignment) RAB27A (P51159) - 6HUF_F 35.47 2.0E-23 GNP
(view alignment) RABA1A (P28185) - 5XR7_A 37.42 1.0E-25 GTP
(view alignment) RAB27A (P51159) - 6HUF_O 35.47 2.0E-23 GNP
(view alignment) RABA1A (P28185) - 5XR4_A 38.04 4.0E-26 GDP
(view alignment) RAB35 (Q15286) DENND1B (Q6P3S1) 3TW8_B 39.34 7.0E-30 -
(view alignment) RAB8A (P61006) OCRL (Q01968) 3QBT_G 37.85 7.0E-29 GNP
(view alignment) Rab6 (O18334) - 2Y8E_B 37.2 1.0E-23 GNP
(view alignment) RAB1B (Q9H0U4) drrA (Q29ST3) 5O74_H 36.93 8.0E-27 9MN GDP
(view alignment) RAB1B (Q9H0U4) TBC1D20 (Q96BZ9) 4HLQ_D 37.14 6.0E-27 GDP
(view alignment) (Q7YYW6) - 2RHD_A 37.71 1.0E-27 GDP
(view alignment) RAB27A (P51159) - 6HUF_H 35.47 2.0E-23 GNP
(view alignment) Rab7a (P51150) Osbpl1a (Q91XL9) 5Z2M_C 36.57 7.0E-28 GTP
(view alignment) RAB1A (P62820) drrA (Q5ZSQ3) 3L0I_D 37.14 3.0E-27 -
(view alignment) RAB1B (Q9H0U4) MICALCL (Q6ZW33) 5SZK_B 36.93 4.0E-26 GNP
(view alignment) RAB35 (Q15286) DENND1A (Q8TEH3) 6EKK_D 39.66 1.0E-29 GDP
(view alignment) RAB1B (Q9H0U4) drrA (Q29ST3) 5O74_F 36.93 8.0E-27 9MN GDP
(view alignment) RAB8A (P61006) RAB3IP (Q96QF0) 4LHY_B 36.32 1.0E-28 GDP
(view alignment) RAB10 (P61026) MICAL1 (Q8TDZ2) 5LPN_A 42.35 1.0E-32 GNP
(view alignment) RAB1B (Q9H0U4) TBC1D20 (Q96BZ9) 4HLQ_H 37.14 6.0E-27 GDP
(view alignment) RAB6B (Q9NRW1) - 2FFQ_A 36.26 2.0E-25 GSP
(view alignment) Rab3 (P25228) - 4RKF_A 37.99 3.0E-26 GNP
(view alignment) RAB8A (P61006) - 4LHV_C 37.71 3.0E-28 GDP
(view alignment) RAB27A (P51159) - 6HUF_M 35.47 2.0E-23 GNP
(view alignment) RAB1A (P62820) - 3SFV_A 37.14 4.0E-27 GDP
(view alignment) RAB1A (P62820) ARF6 (P62330), (Q7DB50) 4FME_B 37.14 3.0E-27 GDP
(view alignment) YPT1 (P01123) GDI1 (P39958) 1UKV_Y 36.63 8.0E-25 GDP GER
(view alignment) RAB27A (P51159) - 6HUF_I 35.47 2.0E-23 GNP
(view alignment) RAB27A (P51159) - 6HUF_L 35.47 2.0E-23 GNP
(view alignment) RAB1A (P62820) virA (Q7BU69) 4FMB_B 37.14 8.0E-27 GDP
(view alignment) RAB32 (Q13637) ANKRD27 (Q96NW4) 4CYM_C 74.86 3.0E-76 GCP
(view alignment) RAB43 (Q86YS6) - 2HUP_A 37.8 4.0E-24 GDP
(view alignment) RAB1A (P62820) (Q7DB50) 4FMC_F 42.02 9.0E-23 GDP
(view alignment) RAB1B (Q9H0U4) drrA (Q29ST3) 5O74_D 36.93 8.0E-27 9MN GDP
(view alignment) SEC4 (P07560) SEC2 (P17065) 4ZDW_A 36.09 6.0E-24 GDP
(view alignment) RAB6A (P20340) - 2GIL_C 37.2 4.0E-24 GTP
(view alignment) YPT1 (P01123) GDI1 (P39958) 2BCG_Y 36.63 8.0E-25 GDP TRS
(view alignment) RAB1B (Q9H0U4) drrA (Q29ST3) 5O74_B 36.93 8.0E-27 9MN GDP
(view alignment) RAB1A (P62820) drrA (Q5ZSQ3) 2WWX_A 36.57 4.0E-26 -
(view alignment) RAB6A (P20340) - 2GIL_A 37.2 4.0E-24 GTP
(view alignment) RAB8A (P61006) - 4LHW_E 37.71 3.0E-28 GNP
(view alignment) RAB6A (P20340) Kif20a (P97329) 5LEF_A 36.59 3.0E-23 GTP
(view alignment) RAB32 (Q13637) (Q6EAT3) 5OEC_B 74.29 1.0E-75 MLY GDP
(view alignment) Rab7a (P09527) Chm (P37727) 1VG9_F 36.46 2.0E-29 P33 GDP
(view alignment) Rab8a (P55258) RABIF (P47224) 2FU5_C 37.43 2.0E-28 -
(view alignment) RAB6A (P20340) Dennd5a (Q6PAL8) 3CWZ_A 36.59 3.0E-23 GTP
(view alignment) YPT1 (P01123) TRS31 (Q03337), BET3 (P36149), TRS23 (Q03784), BET5 (Q03630) 3CUE_X 36.63 8.0E-25 -
(view alignment) RAB8A (P61006) RAB3IP (Q96QF0) 4LHZ_A 36.32 1.0E-28 GTP
(view alignment) RAB4B (P61018) - 2O52_B 36.07 2.0E-24 GDP
(view alignment) RAB8A (P61006) RAB3IP (Q96QF0) 4LHX_B 36.32 1.0E-28 -
(view alignment) RAB8A (P61006) (Q5ZWZ3) 3TNF_A 37.85 7.0E-29 GNP
(view alignment) RAB8A (P61006) - 4LHW_D 37.71 3.0E-28 GNP
(view alignment) RAB1A (P62820) - 2FOL_A 36.93 2.0E-27 GDP
(view alignment) Rab7a (P09527) - 1VG1_A 36.46 2.0E-29 GDP
(view alignment) RAB1B (Q9H0U4) drrA (Q5ZSQ3) 3JZA_A 37.14 6.0E-27 -
(view alignment) (G0SGE1) (G0SD94), (G0SGS3) 5LDD_F 36.31 9.0E-30 -
(view alignment) RAB8A (P61006) - 4LHV_E 37.71 3.0E-28 GDP
(view alignment) RAB6B (Q9NRW1) - 2E9S_B 36.26 2.0E-25 GDP
(view alignment) Rab8a (P55258) RABIF (P47224) 2FU5_D 37.43 2.0E-28 -
(view alignment) RAB2A (P61019) - 1Z0A_C 36.63 2.0E-24 GDP
(view alignment) SEC4 (P07560) - 4Z8Y_A 36.09 6.0E-24 GDP
(view alignment) (G0SGE1) (G0SD94), (G0SGS3) 5LDD_C 36.31 9.0E-30 -
(view alignment) RAB6A (P20340) - 2GIL_B 37.2 4.0E-24 GTP
(view alignment) RAB8A (P61006) RAB3IP (Q96QF0) 4LHY_A 36.32 1.0E-28 GDP
(view alignment) RAB8A (P61006) RAB3IP (Q96QF0) 4LHX_A 36.32 1.0E-28 -
(view alignment) RAB27A (P51159) - 6HUF_C 35.47 2.0E-23 GNP
(view alignment) RAB32 (Q13637) ANKRD27 (Q96NW4) 4CZ2_A 76 9.0E-78 GCP
(view alignment) RAB1B (Q9H0U4) - 3NKV_A 37.14 6.0E-27 GNP AMP
(view alignment) Rab7a (P51150) Osbpl1a (Q91XL9) 5Z2M_A 36.57 7.0E-28 GTP
(view alignment) RAB1B (Q9H0U4) drrA (Q29ST3) 5O74_J 36.93 8.0E-27 9MN GDP
(view alignment) RAB1A (P62820) - 3TKL_A 37.14 3.0E-27 GTP
(view alignment) RAB2B (Q8WUD1) - 2A5J_A 36.9 2.0E-26 GDP
(view alignment) SEC4 (P07560) SEC2 (P17065) 2EQB_A 35.43 4.0E-24 -
(view alignment) RAB1B (Q9H0U4) drrA (Q29ST3) 5O74_L 36.93 8.0E-27 9MN GDP
(view alignment) RAB6A (P20340) - 1YZQ_A 36.59 2.0E-24 GNP
(view alignment) RAB35 (Q15286) DENND1A (Q8TEH3) 6EKK_C 39.66 1.0E-29 GDP
(view alignment) SEC4 (P07560) GDI1 (P39958) 3CPH_A 35.67 1.0E-23 GDP
(view alignment) RAB3B (P20337) - 3DZ8_A 37.43 8.0E-28 GDP
(view alignment) Rab3 (P25228) - 4RKF_B 37.99 3.0E-26 GNP
(view alignment) RAB2A (P61019) - 1Z0A_A 36.63 2.0E-24 GDP
(view alignment) RAB8A (P61006) RAB3IL1 (Q8TBN0) 4LI0_B 36.32 1.0E-28 GDP
(view alignment) RAB27A (P51159) - 6HUF_J 35.47 2.0E-23 GNP
(view alignment) RAB32 (Q13637) ANKRD27 (Q96NW4) 4CZ2_C 76 9.0E-78 GCP
(view alignment) RAB10 (P61026) MICAL1 (Q8TDZ2) 5LPN_C 42.35 1.0E-32 GNP
(view alignment) YPT1 (P01123) - 1YZN_A 35.59 9.0E-25 GNP
(view alignment) YPT1 (P01123) TRS31 (Q03337), BET3 (P36149), TRS23 (Q03784), BET5 (Q03630) 3CUE_L 36.63 8.0E-25 -
(view alignment) RABA1A (P28185) - 5XR6_A 38.04 4.0E-26 GNP
(view alignment) Rab7a (P09527) Chm (P37727) 1VG9_D 36.46 2.0E-29 P33 GDP
(view alignment) RAB1A (P62820) (Q7DB50) 4FMD_F 37.5 4.0E-25 GDP
(view alignment) RAB1B (Q9H0U4) (Q5ZSM7) 4I1O_A 37.14 6.0E-27 GDP
(view alignment) RAB8A (P61006) - 4LHW_A 37.71 3.0E-28 GNP
(view alignment) RAB35 (Q15286) RUSC2 (Q8N2Y8) 6IF2_B 38.8 8.0E-29 GTP
(view alignment) RAB1A (P62820) (Q7DB50) 4FMD_B 37.14 3.0E-27 GDP
(view alignment) RAB27A (P51159) - 6HUF_P 35.47 2.0E-23 GNP
(view alignment) Rab7a (P09527) Chm (P37727) 1VG9_H 36.46 2.0E-29 P33 GDP
(view alignment) RAB32 (Q13637) ANKRD27 (Q96NW4) 4CZ2_B 76 9.0E-78 GCP
(view alignment) YPT1 (P01123) TRS31 (Q03337), BET3 (P36149), TRS23 (Q03784), BET5 (Q03630) 3CUE_F 36.63 8.0E-25 -
(view alignment) RAB27A (P51159) - 6HUF_N 35.47 2.0E-23 GNP
(view alignment) RAB1B (Q9H0U4) (Q5ZSM7) 4I1O_C 37.14 6.0E-27 GDP
(view alignment) RAB3D (O95716) - 2GF9_A 36.42 3.0E-25 GDP
(view alignment) RAB8A (P61006) - 4LHW_B 37.71 3.0E-28 GNP
(view alignment) RAB8A (P61006) OCRL (Q01968) 3QBT_A 37.85 7.0E-29 GNP
(view alignment) RAB8A (P61006) MICALCL (Q6ZW33) 5SZI_A 36.32 1.0E-28 GNP
(view alignment) RAB1A (P62820) drrA (Q5ZSQ3) 3L0I_B 37.14 3.0E-27 -
(view alignment) RABA1A (P28185) - 5XR7_B 37.42 1.0E-25 GTP
(view alignment) RAB27A (P51159) - 6HUF_K 35.47 2.0E-23 GNP
(view alignment) RAB1B (Q9H0U4) MICALCL (Q6ZW33) 5SZH_B 37.14 7.0E-27 GNP
(view alignment) RAB1A (P62820) (G9EPL4) 4JVS_B 37.14 3.0E-27 GDP
(view alignment) RAB8A (P61006) - 4LHW_C 37.71 3.0E-28 GNP
(view alignment) RAB8A (P61006) OCRL (Q01968) 3QBT_E 37.85 7.0E-29 GNP
(view alignment) RAB1B (Q9H0U4) (Q5ZSM7) 4I1O_G 37.14 6.0E-27 GDP
(view alignment) RAB1A (P62820) (Q5ZSM7) 4IRU_F 37.14 3.0E-27 GDP
(view alignment) RAB1B (Q9H0U4) (Q5ZSM7) 4I1O_E 37.14 6.0E-27 GDP
(view alignment) RAB35 (Q15286) ACAP2 (Q15057) 6IF3_B 38.8 8.0E-29 GTP
(view alignment) RAB2A (P61019) - 1Z0A_D 36.63 2.0E-24 GDP
(view alignment) RAB1A (P62820) ARF6 (P62330), (Q7DB50) 4FME_E 37.14 3.0E-27 GDP
(view alignment) RAB35 (Q15286) DENND1B (Q6P3S1) 3TW8_D 39.34 7.0E-30 -
(view alignment) RAB32 (Q13637) ANKRD27 (Q96NW4) 4CYM_A 74.86 3.0E-76 GCP
(view alignment) RAB32 (Q13637) (Q6EAT3) 5OED_B 75.43 3.0E-77 MLY GDP
(view alignment) RAB32 (Q13637) - 6FF8_B 74.86 2.0E-76 GTP
(view alignment) RAB8A (P61006) OCRL (Q01968) 3QBT_C 37.85 7.0E-29 GNP
(view alignment) Rab3a (P63012) - 3RAB_A 36.26 2.0E-26 GNP
(view alignment) RAB43 (Q86YS6) - 2HUP_B 37.8 4.0E-24 GDP
(view alignment) RAB12 (Q6IQ22) - 2IL1_A 35.29 5.0E-26 GDP
(view alignment) RAB1B (Q9H0U4) TBC1D20 (Q96BZ9) 4HLQ_B 37.14 6.0E-27 GDP
(view alignment) RAB6B (Q9NRW1) - 2FE4_A 36.26 2.0E-25 GDP
(view alignment) RAB6A (P20340) Kif20a (P97329) 5LEF_B 36.59 3.0E-23 GTP
(view alignment) RAB10 (P61026) MICALCL (Q6ZW33) 5SZJ_A 42.35 2.0E-32 GNP
(view alignment) RAB1A (P62820) (Q5ZSM7) 4IRU_B 37.14 3.0E-27 GDP
(view alignment) RAB1A (P62820) virA (Q7BU69) 4FMB_F 37.14 8.0E-27 GDP
(view alignment) RAB6B (Q9NRW1) - 2E9S_C 36.26 2.0E-25 GDP
(view alignment) Rab7a (P09527) Chm (P37727) 1VG9_B 36.46 2.0E-29 P33 GDP
(view alignment) RAB8A (P61006) - 4LHV_A 37.71 3.0E-28 GDP
(view alignment) RAB8A (P61006) - 4LHV_D 37.71 3.0E-28 GDP
(view alignment) YPT1 (P01123) TRS31 (Q03337), BET3 (P36149), TRS23 (Q03784), BET5 (Q03630) 3CUE_R 36.63 8.0E-25 -
(view alignment) RAB32 (Q13637) - 6FF8_A 74.86 2.0E-76 GTP
(view alignment) RAB6A (P20340) - 2GIL_D 37.2 4.0E-24 GTP
(view alignment) RAB1A (P62820) (Q7DB50) 4FMC_D 37.14 3.0E-27 GDP
(view alignment) RAB1B (Q9H0U4) TBC1D20 (Q96BZ9) 4HLQ_J 37.14 6.0E-27 GDP
(view alignment) RAB6B (Q9NRW1) - 2E9S_A 36.26 2.0E-25 GDP
(view alignment) RAB1A (P62820) (Q7DB50) 4FMD_D 37.14 3.0E-27 GDP
(view alignment) SEC4 (P07560) SEC2 (P17065) 2OCY_C 35.67 1.0E-23 -
(view alignment) RAB32 (Q13637) ANKRD27 (Q96NW4) 4CYM_B 74.86 3.0E-76 GCP
(view alignment) RAB1A (P62820) (Q7DB50) 4FMC_B 37.14 3.0E-27 GDP
(view alignment) RAB1A (P62820) (Q5ZSM7) 4IRU_D 37.14 3.0E-27 GDP
(view alignment) Rab6 (O18334) - 2Y8E_A 37.2 1.0E-23 GNP
(view alignment) RAB1B (Q9H0U4) - 3NKV_B 37.14 6.0E-27 GNP AMP
(view alignment) RABA1A (P28185) - 5XR4_B 38.04 4.0E-26 GDP
(view alignment) RAB8A (P61006) RAB3IP (Q96QF0) 4LHZ_B 36.32 1.0E-28 GTP
(view alignment) RAB27A (P51159) - 6HUF_G 35.47 2.0E-23 GNP
(view alignment) RAB8A (P61006) - 4LHV_B 37.71 3.0E-28 GDP
(view alignment) RAB27A (P51159) - 6HUF_E 35.47 2.0E-23 GNP
(view alignment) RAB27A (P51159) - 6HUF_B 35.47 2.0E-23 GNP
(view alignment) RAB2A (P61019) - 1Z0A_B 36.63 2.0E-24 GDP
(view alignment) (Q26000) - 1D5C_A 41.51 3.0E-26 GDP
(view alignment) RAB7A (P51149) OSBPL1A (Q9BXW6) 6IYB_A 35.91 3.0E-27 GTP
(view alignment) RAB4B (P61018) - 2O52_A 36.07 2.0E-24 GDP
(view alignment) SEC4 (P07560) - 4Z8Y_B 36.09 6.0E-24 GDP
(view alignment) RAB27A (P51159) - 6HUF_D 35.47 2.0E-23 GNP
(view alignment) RAB7A (P51149) OSBPL1A (Q9BXW6) 6IYB_C 35.91 3.0E-27 GTP
(view alignment) RAB1B (Q9H0U4) TBC1D20 (Q96BZ9) 4HLQ_F 37.14 6.0E-27 GDP
(view alignment) RAB27A (P51159) - 6HUF_A 35.47 2.0E-23 GNP
(view alignment) RAB1A (P62820) virA (Q7BU69) 4FMB_D 37.14 8.0E-27 GDP
(view alignment) RABA1A (P28185) - 5XR6_B 38.04 4.0E-26 GNP
(view alignment) RAB18 (Q9NP72) - 1X3S_A 37.87 2.0E-23 GNP
(view alignment) RAB8A (P61006) RAB3IL1 (Q8TBN0) 4LI0_A 36.32 1.0E-28 GDP
(view alignment) (O18333) - 4RKE_A 36.05 1.0E-23 GNP